Clinical trials: Arterial Catheterization
Pulmonary Arterial Hypertension
Pharmacokinetics, Safety and Efficacy of BIA 5-1058 in PAH (Zamicastat)
This Study evaluates the pharmacokinetic (PK) profile of different zamicastat doses in Pulmonary arterial hypertension (PAH) patients to find the most promising therapeutic dosage range for the treatment of PAH disease
- Trial name
- NCT04316143
- Testing
- Oral zamicastat
- Where
- 13 sites in Austria, Germany and 5 more
- Volunteers
- 33 people
- Sponsor
- Bial - Portela C S.A.
Heart Disease, Coronary, Chest Pain
The Computed Tomography-derived Fractional Flow Reserve STAT Trial
This study is designed to directly compare Standard Care and CT fractional flow reserve (CTFFR) for diagnosis of chest pain patients with definite coronary artery disease (CAD) on heart computed tomography (CT) scans.
- Conditions
- Heart Disease, Coronary, Chest Pain, Acute Coronary Syndrome
- Trial name
- CTFFR-STAT (NCT03263806)
- Testing
- CTFFR-Guided Group Management, SOC Group Management
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Corewell Health East
Knee Osteoarthritis, Chronic Pain
Motor Cortex Plasticity and the Effect of Deep Intramuscular Needling Stimulation Therapy (DIMST) in Osteoarthritis Pain
The aim of this study is to evaluate the cortical excitability in pain of knee osteoarthritis (OA), as well as the effect of one session of a kind of electroacupuncture (deep needling intramuscular stimulation therapy - DIMST) in…
- Trial name
- NCT01855958
- Testing
- DIMST
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Radial Artery Spasm, Angina
Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention
The primary objective of the study is to determine the role of transdermal vasodilators as an adjunct to parenteral vasodilators in reducing radial artery spasm, improving patient comfort, and post procedure radial artery patency…
- Conditions
- Radial Artery Spasm, Angina, Coronary Artery Disease
- Trial name
- TNT-RASP (NCT02832115)
- Testing
- Topical Nitroglycerine, Topical Lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Aultman Health Foundation
Plantar Fascitis, Myofacial Pain Syndromes
A Comparative Study of Two Dry Needling Interventions for Plantar Heel Pain
This is a clinical trial that will be done in the state of Kuwait, at the physical rehabilitation medicine hospital. the participants will be recruited from all over Kuwait, there is a clinical registry upon the ethical committee…
- Conditions
- Plantar Fascitis, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- NCT03236779
- Testing
- dry needling
- Where
- Kuwait
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Coronary Angiography, Coronary Angioplasty
DIstal vs Proximal Radial Artery Access for Cath
This single-center, prospective, randomized study will evaluate distal radial artery (dRA) vs. proximal radial artery access (pRA) in regards to hand function and radial artery occlusion.
- Trial name
- DIPRA (NCT04318990)
- Testing
- Distal radial artery access, Proximal radial artery surgery
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Baylor Research Institute
Surgery, Arterial Catheterization, Peripheral
Feasibility of Obtaining Pulse Oximetry Readings From the Oropharynx
This is a prospective study to evaluate the feasibility of obtaining a pulse oximetry ready from the oropharynx with a standard oximeter probe that has been attached to an oral airway or a tongue blade.
- Trial name
- NCT05690633
- Testing
- Pulse oximetry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Joseph D. Tobias
Bruxism, Sleep Bruxism, Adult
Comparison of Dry Needling and Two Botulinum Toxins for Bruxism
1. Aim: The aim of this study is to prospectively compare the clinical efficacy of Dry Needling (DN), Nabota (PrabotulinumtoxinA), and Dysport (AbobotulinumtoxinA) treatments on the thickness of masseter and anterior temporal…
- Conditions
- Bruxism, Sleep Bruxism, Adult, Awake Bruxism, Masseter Muscle Hypertrophy
- Trial name
- NCT07452510
- Testing
- Dry Needling (DN), PrabotulinumtoxinA, Abobotulinumtoxina
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Tayyip Erdogan University
Anorexia Nervosa, Cancer
The Effectiveness and Mechanism Study of Auricular Needling in Treating Cancer Induced Anorexia
Controlling of cancer induced anorexia is highly demanded by advanced cancer patients. It plays an important role in improving the quality of life among advanced cancer patients.
- Trial name
- NCT02887586
- Testing
- auricular needling
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Contrast-induced Acute Kidney Injury
Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury
This a prospective, double-blind, sham-controlled, randomized clinical trial to study the effects of remote ischemic preconditioning on acute kidney injury, vascular and renal biomarkers in patients with non-ST elevation…
- Trial name
- BRICK (NCT03236441)
- Testing
- RIPC
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Oladipupo Olafiranye, MD, MS
Neck Pain
Dry Needling in Patients With Chronic Neck Pain
The investigators study the efficacy of a combination of dry needling plus manual therapy against sham dry needling plus manual therapy in the treatment of chronic neck pain.
- Trial name
- NCT02435966
- Testing
- Dry needling, Manual therapy
- Volunteers
- 131 people
- Sponsor
- European University of Madrid
Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis
Safety and Effectiveness Study of the Ensure Medical Vascular Closure Device
The purpose of this study is to determine whether the Ensure Medical Vascular Closure Device is more effective than standard manual compression at sealing the puncture made in the femoral artery following a cardiac or peripheral…
- Conditions
- Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis, Peripheral Arteriosclerosis
- Trial name
- NCT00345631
- Testing
- Manual Compression, Vascular Closure Device
- Where
- 17 sites in United States
- Volunteers
- 488 people
- Sponsor
- Cordis US Corp.
Coronary Artery Disease
CorPath™ 200: Robotically-Assisted Percutaneous Coronary Intervention (PCI)
An open-label, prospective, single-arm study is designed to evaluate safety, clinical and technical efficacy of the CorPath 200 System in delivery and manipulation of the coronary guide wires and balloon/stent systems for use in…
- Trial name
- NCT01076036
- Testing
- CorPath 200
- Where
- Colombia
- Volunteers
- 8 people
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Time to Insertion of Radial Artery Cannulation
Ultrasound-guided Versus Direct Palpation Radial Artery Catheter Insertion Among Cardiac Anesthesiologists
When a patient undergoes heart surgery, their Anesthesiologist will insert a tiny plastic tube, called a catheter, in the artery of the patient's wrist. This is called a radial artery catheter.
- Trial name
- art-line (NCT02118441)
- Testing
- Ultrasound-guided Radial Artery Catheter Insertion, Direct Palpation-guided Radial Artery Catheter insertion
- Where
- Canada
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Vascular Access Complications, Cardiac Catheterization
Femoral Arterial Access With Ultrasound Trial
This study is designed to evaluate the routine use of vascular ultrasound as an aid for proper placement of a femoral arterial sheath during cardiac catheterization and peripheral arterial angiography.
- Conditions
- Vascular Access Complications, Cardiac Catheterization, Peripheral Vascular Disease
- Trial name
- FAUST (NCT00667381)
- Testing
- Real-time Ultrasound Guidance (Site-Rite 5 or 6 machine)
- Where
- 4 sites in United States
- Volunteers
- 1,014 people
- Sponsor
- University of California, Irvine
Coronary Artery Disease
Comparison of Intravenous Adenosine Infusion With Regadenoson Bolus for Inducing Maximal Coronary Hyperemia
The purpose of this study is to determine if regadenoson is as safe and effective as adenosine when used in the cardiac catheterization lab during measurement of coronary flow reserve and fractional flow reserve.
- Trial name
- NCT01161121
- Testing
- adenosine, regadenoson
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- St. Louis University
Chronic Renal Insufficiency, Diabete Mellitus
Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure
To evaluate cardio-renal and overall safety profile of GE 145 320 mg I/ml Injection when compared to iopamidol 370 mg I/mL. The study will focus on elderly subjects with either chronic renal insufficiency, or diabetes mellitus…
- Conditions
- Chronic Renal Insufficiency, Diabete Mellitus, Congestive Heart Failure
- Trial name
- NCT01252810
- Testing
- GE-145
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- GE Healthcare
Coronary Artery Disease
Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease
Cardiac catheterization with invasive coronary angiography is the gold standard for determining the presence or absence of significant coronary heart disease (CHD).
- Trial name
- NCT04272060
- Testing
- CT angiography, Invasive coronary angiography
- Where
- 3 sites in United States, Brazil and 1 more
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins University
Fibrosing Alopecia, Frontal Fibrosing Alopecia
Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling
To evaluate the efficacy microneedling via a professional tattoo machine in revitalizing hair follicles in patients with fibrosing alopecia.
- Conditions
- Fibrosing Alopecia, Frontal Fibrosing Alopecia, Central Centrifugal Cicatricial Alopecia
- Trial name
- NCT04342091
- Testing
- SOL Nova Device
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Myocardial Ischemia, Acute Coronary Syndrome
EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)
The purpose of this study is to see if early INTEGRILIN® (eptifibatide) therapy in patients with non-ST-segment elevation acute coronary syndrome (ACS) reduces the occurence of death, heart attack and urgent cardiac intervention…
- Trial name
- NCT00089895
- Testing
- Eptifibatide (Integrilin)
- Volunteers
- 9,406 people
- Sponsor
- Organon and Co