Clinical trials: Arachnophobia
Arachnophobia, Cynophobia
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs.
- Conditions
- Arachnophobia, Cynophobia, Ophidiophobia
- Trial name
- NCT06302868
- Testing
- Telemedicine Exposure Therapy Using Photos and Videos, Telemedicine-Based Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of South Florida
Fear of Spiders, Acute Stress Reaction
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
This clinical trial aims to evaluate the nature and duration of effects of three FDA-approved medications (propranolol and hydrocortisone) on military-relevant cognitive, emotional, and motor performance following an exposure to…
- Trial name
- NCT06982183
- Testing
- Propranolol, Hydrocortisone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Anxiety, Anxiety Disorders
In Vivo Exposure vs. Videochat-Based Vicarious Exposure
After screening (including parts of the Mini-DIPS), participants will receive a pre-assessment with a baseline heartrate measurement, self-report measures and two BATs (with the treated spider and the non-treated spider).
- Trial name
- NCT07432945
- Testing
- In Vivo Exposure Training (IVET), Vicarious Exposure Training (VicET)
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Ruhr University of Bochum
One Week Follow-up Assessment, Six Weeks Follow-up Assessment
The Effect of Time on Generalization of Exposure-based Benefit
Participants will receive a pre-assessment and an exposure with a control spider. This control spider will be presented again at post-training assessments.
- Conditions
- One Week Follow-up Assessment, Six Weeks Follow-up Assessment, Three Months Follow-up Assessment
- Trial name
- NCT06255821
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Ruhr University of Bochum
Spider Fear, Arachnophobia
Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals
The effectiveness of an optimized extinction training is investigated in spider-fearful individuals. Participants will undergo a one-session standardized extinction training, either with or without occasional metal imagination of…
- Trial name
- NCT05424250
- Testing
- occasional aversive imagination, Exposure
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Philipps University Marburg
Spider Fear, Arachnophobia
Feasibility of an Online Modeled Exposure in Spider Fearful Individuals
The effectiveness of an optimized group exposure treatment is investigated in spider-fearful individuals. Participants will undergo an optimized standardized exposure treatment.
- Trial name
- OMEX (NCT06182709)
- Testing
- online psychoeducation video + modeled exposure, live psychoeducation video + modeled exposure, group exposure
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Philipps University Marburg
Spider Phobia
Gamification in the Treatment of Spider Phobia
Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with…
- Trial name
- NCT04423783
- Testing
- 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Anke Haberkamp
Fear of Spiders
The Neural Mechanisms of Imaginal Extinction
Imaginal exposure is a widely used and effective psychological treatment technique in which patients are exposed to fearful stimuli and situations using mental imagery.
- Trial name
- NCT05168592
- Testing
- Threat conditioning, Imaginal extinction
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fear of Spiders
Neural Mechanisms of Imaginal and in Vivo Exposure
Imaginal exposure is a widely used and effective psychological treatment technique. Recent research suggests that neural activations and emotional responses during imaginal exposure are similar to those elicited during in vivo…
- Trial name
- NCT05193383
- Testing
- Imaginal exposure, Exposure, Approach-avoidance conflict
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fear of Spiders, Fear of Heights
Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure
This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of…
- Trial name
- NCT03907345
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Phobias Snakes, Phobias Spiders
Bringing Exposure Therapy to Real-Life Context With Augmented Reality
In this patented project, U.S. Patent No. 10,839,707, the investigators will develop an augmented reality exposure therapy method for arachnophobia, and fear of snakes, to test in the clinic.
- Trial name
- ARET (NCT03649347)
- Testing
- Augmented reality exposure therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wayne State University
Specific Phobia, Arachnophobia
Use of Safety Behaviors in Exposure Therapy for Arachnophobia
This study examines the impact of safety behaviors (i.e., unnecessary protective actions) on outcomes of exposure therapy for spider phobia.
- Conditions
- Specific Phobia, Arachnophobia, Spider Phobia
- Trial name
- NCT04470882
- Testing
- Exposure with faded safety behaviors, Exposure without safety behaviors, Exposure with unfaded safety behaviors
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Nevada, Reno
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Spider Phobia
One-session Treatment for Spider Fears
Despite the efficacy of exposure and response prevention (ERP) for anxiety and phobias, recent theoretical research on fear extinction via inhibitory learning suggests that cognitive restructuring (CR)--the explicit challenging…
- Trial name
- NCT03410264
- Testing
- CR-EXP, EXP-CR, Stress Management
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of North Carolina, Chapel Hill
Claustrophobia, Obsessive-Compulsive Disorder
Efficacy of Targeted Memory Reactivation for Enhancing Exposure Therapy
This study evaluates whether a scent applied during exposure therapy and during subsequent sleep will increase the durability of treatment effects for individuals with fear of spiders, contamination, and enclosed spaces.
- Conditions
- Claustrophobia, Obsessive-Compulsive Disorder, Arachnophobia
- Trial name
- NCT04663672
- Testing
- Experimental Scent, Control Scent, No-Scent Control
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Texas at Austin
Specific Phobia
Spider Phobia Opposite Action Treatment Study
This study tests the effectiveness of exposure therapy for fear of spiders as enhanced by the use of antagonistic or opposite actions during treatment.
- Trial name
- NCT02905279
- Testing
- Biofeedback Relaxation Training, Exposure Therapy, Exposure with Threat-Relevant Opposite Actions
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Specific Phobias
tDCS-Augmented Exposure Therapy for Pathological Fear
This double-blind randomized controlled clinical trial aims to test whether transcranial direct current stimulation (tDCS) can be used to modulate fear extinction learning during exposure therapy for pathological fear, including…
- Trial name
- NCT03095482
- Testing
- Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Fear of Spiders
Efficacy of a Gamified Augmented Reality Exposure-based Application in Subjects With Fear of Spiders
Investigation of the efficacy of a gamified augmented reality exposure app in individual with fear of spiders.
- Trial name
- GARET2019 (NCT04162509)
- Testing
- AR app
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Anxiety Disorders, Arachnophobia
Optimizing Exposure Therapy With Mental Rehearsal
Treatment response rates for cognitive behavioral therapy (CBT) across anxiety disorders average approximately 50% post-treatment (Loerinc et al, 2015), evidencing significant 'return of fear', the re-emergence of a partially or…
- Trial name
- NCT03934385
- Testing
- Mental Rehearsal, Exposure
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Specific Phobia
Effects of Stress on Exposure Therapy
This study investigates whether stress can augment exposure therapy outcome in patients with specific phobia (spider phobia).
- Trial name
- NCT03505437
- Testing
- Cold water condition, Warm water condition
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Ruhr University of Bochum