Clinical trials: Appetite Control
Glycemic Control, Subjective Appetite
Sugars-sweetened Beverages and Exercise on Glycaemic Response and Subjective Appetite in Children
The purpose of the study is to understand the role chocolate milk compared to a fruit drink, with and without exercise, on glycaemic regulation and subjective appetite in children.
- Trial name
- NCT02197195
- Testing
- Chocolate Milk, Fruit Drink, Exercise
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Ketosis
Markers of Appetite Regulation During Exogenous Ketosis
The aim of this study is to investigate the relationship, if any, between markers of satiety, desire to eat, hunger, and metabolic markers of the regulation hereof during ketosis as compared with a Glucose-containing and a…
- Trial name
- MARK (NCT04156477)
- Testing
- Ketone ester, Glucose, Tap water
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Central Jutland Regional Hospital
Obesity, Normal Weight
Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)
The overall aim of the MEMORY study is to examine the concept of 'food memory' - how specific macronutrient compositions influence subsequent food preference and intake, and whether this differs across the BMI range from normal…
- Conditions
- Obesity, Normal Weight, Overweight
- Trial name
- MEMORY (NCT06752967)
- Testing
- High protein liquid test meal, High carbohydrate liquid test meal
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Obesity & Overweight, Cardiometabolic Health Indicators
Tirzepatide Impact Assessment Study
This study examines how two different weight-loss strategies affect heart and metabolic health, as well as changes at the molecular level in the body.
- Conditions
- Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders
- Trial name
- TIA (NCT07740291)
- Testing
- GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Pediatric Obesity
Energy Intake and Energy Deficit in Obese Adolescents
The aim of the present study is to compare the effect of two weight loss interventions inducing the same energy deficit but one based on exercise and one using dietary restriction, on appetite control in obese adolescents.
- Trial name
- IDEFIX (NCT03466359)
- Testing
- DEF-EI : Energy restriction induced energy deficit, DEF-EX : Exercise induced energy deficit
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Energy Balance, Physiology - Regulation of Appetite and Food Intake
The Role of Estradiol and Progesterone on Appetite Regulation and Energy Balance
The goal of this study is to determine if estradiol and progesterone are involved in appetite regulation and energy balance. The study aims to complete a 13 day randomized controlled trial (RCT) where oral supplementation of…
- Trial name
- E2 & P4 in EB (NCT07620587)
- Testing
- Estradiol Only, Progesterone Only, Estradiol and Progesterone Combination
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Prediabetes
Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes
The goal of this clinical trial is to learn if Dihydroberberine (DHB) supplementation affects adults with pre-diabetes. The main questions it aims to answer are: Does DHB supplementation increase the concentration of GLP-1 in the…
- Trial name
- DHB (NCT07210684)
- Testing
- Dihydroberberine（DHB）400 mg
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nanjing Nutrabuilding Bio-tech Co., Ltd.
Appetitive Behavior
Effect of Oral Lactate Ingestion on Appetite Regulation
The goal if this study is to determine how oral lactate ingestion affects markers of appetite regulation. Researchers will compare oral lactate ingestion to a sodium chloride placebo.
- Trial name
- NCT06379815
- Testing
- Sodium Lactate, Sodium Chloride
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Healthy, Overweight (BMI > 25)
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or…
- Conditions
- Healthy, Overweight (BMI > 25), Overweight , Obesity, Male
- Trial name
- ProBiSat (NCT07715955)
- Testing
- Probiotic supplementation
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Anorexia, Cancer Cachexia
The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung Cancers
This trail will be carried out to evaluated the effect and safety of acupuncture for the anorexia in patients with gastrointestinal tract and lung cancers.
- Trial name
- NCT02619266
- Testing
- Acupuncture, Megestrol Acetate
- Where
- 4 sites in China
- Volunteers
- 160 people
- Sponsor
- Xinqiao Hospital of Chongqing
Failure to Thrive
Appetite Regulation in Children With Failure to Thrive
Failure to thrive (FTT) is an expression for inadequate growth in the early childhood and thus, a sign of undernutrition. This study will include children with FTT, and compare with existing data from children with normal and…
- Trial name
- NCT02647580
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Lena Kirchner Brahe
Obesity, Weight Loss
Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted…
- Conditions
- Obesity, Weight Loss, Weight Management, Dietary Intervention
- Trial name
- NCT06809166
- Testing
- Contrave, Diet Program
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Active Video Games and Appetite Control
Active Video Games and Appetite Control in Adolescents
STATEMENT OF THE PROBLEM: Video games have enormous mass appeal, are omnipresent in the daily schedule of most children and youth and have been linked to the obesity epidemic.
- Trial name
- NCT01655901
- Testing
- Active video gaming, Passive video gaming, Resting
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Appetite Regulation, Energy Intake
Impact of Sourdough Bread Consumption on Long-term Energy Intake: A Pilot Study of Feasibility
The present study is a pilot study examining whether long-term sourdough bread consumption reduces energy intake and blood lipids levels over a period of 4 weeks in free-living normalweight and overweight participants.
- Conditions
- Appetite Regulation, Energy Intake, Body Weight Changes, Eating Behavior
- Trial name
- SOBER (NCT05590611)
- Testing
- Dietary Intervention with Brown Bread, Dietary Intervention with Sourdough Bread
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Satiety, Appetite Regulation
A Placebo-Controlled Study Evaluating the Effects of Arrabina on Satiety in Healthy Adults
This study is being conducted to assess the effects of a prebiotic product, Arrabina, on appetite in healthy adults. The goal is to see if this product can help with appetite regulation, support gut health, and support weight…
- Conditions
- Satiety, Appetite Regulation, Weight Control
- Trial name
- NCT06884449
- Testing
- Arrabina Prebiotic 5.0 g, Arrabina Prebiotic 3.5 g
- Where
- 3 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Comet Bio Inc.
Obesity, Diet
Effect of Carbonated Soft Drinks on Appetite-Regulation
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks…
- Trial name
- NCT00776971
- Testing
- Sugar-sweetened soft drink, Aspartame-sweetened soft drink, Semi-skimmed milk
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Obesity, Overweight
A Study of Tirzepatide in Overweight and Very Overweight Participants
The main purpose of this study is to measure the effect of tirzepatide on food intake in participants who are overweight or very overweight.
- Trial name
- NCT04311411
- Testing
- Tirzepatide, Liraglutide
- Where
- 3 sites in United States
- Volunteers
- 114 people
- Sponsor
- Eli Lilly and Company
Malnutrition Elderly, Protein Malnutrition
The Effect of a Plant-based, Protein-dense Sauce on Essential Amino Acid Concentrations and Gut Fullness in Older Adults
The goal of this clinical trial is to determine whether meals fortified with plant-based high protein sauce (ProSauce) provide better metabolic availability of essential amino acids compared to meals with standard lower-protein…
- Trial name
- ProSauce (NCT06965699)
- Testing
- ProSauce, low-protein sauce
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Obesity, Food Craving
Transcranial Magnetic Stimulation (TMS) in Obesity
Obesity is a metabolic disease that has reached epidemic proportions. Insofar no long-term effective drug treatment was developed for obesity.
- Conditions
- Obesity, Food Craving, Appetite and General Nutritional Disorders
- Trial name
- NCT03009695
- Testing
- High frequency repetitive dTMS, Low frequency repetitive dTMS
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale San Donato
Overweight
Efficacy and Safety of Zenoctil in Reducing Body Weight
The intention of the study is to evaluate the safety and potential body weight and body fat loss effects of a 12-week treatment with Zenoctil in a randomized, double-blind, placebo-controlled, parallel study conducted in…
- Trial name
- NCT01423617
- Testing
- Zenoctil
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- InQpharm Group