Clinical trials: Appetite
Appetite, Eating Behavior
Effects of Energy and Physical Density Manipulation on Appetite
As individuals tend to eat a constant weight or volume of food, manipulating physical and energy densities generally results in changes in energy intake without affecting subjective appetite sensations.
- Trial name
- NCT05408390
- Testing
- LPD+LED, HPD+LED, LPD+HED
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Pediatric Obesity
Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.
The aim of the present study is to compare the effect of iso-energetic energy deficits induced by exercise or dietary restriction on energy intake and appetite feelings in adolescents with obesity
- Trial name
- IDEX1 (NCT04739189)
- Testing
- Con : control condition without exercise / rest condition, Def-EX : Condition with an exercise-induced energy deficit, Def-EI : Condition with an energy-restriction energy deficit
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity
Prospective Study of Hormone Levels After Bariatric Surgery
This project will study the effects of surgery for obesity on bone metabolism and hormones that regulate appetite.
- Trial name
- NCT00627315
- Testing
- Gastric bypass, Gastric banding
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity
Effect of Hydroxychloroquine Sulphate in Healthy Lean Females
The effect of an acute administration of hydroxychloroquine sulphate will be investigated on hedonic food intake, appetite related sensations and gastrointestinal hormone release in healthy female subjects.
- Trial name
- PLAQHV (NCT04005768)
- Testing
- Hydroxychloroquine Sulphate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Motivation
A Direct-to-Consumer Study Investigating the Effect of Specific Cannabinoid Products on Motivation, Energy Level, Focus, and Appetite in Healthy Adults
Tetrahydrocannabivarin (THCV) is a rare cannabinoid and is a homologue of THC that differs only in the length of the alkyl side chain (3C vs 5C, respectively).
- Trial name
- NCT06213064
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Phylos Bioscience, Inc.
Obesity
Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.
Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.
- Trial name
- NCT04186026
- Testing
- Saline + saline, Neurotensin + saline, GLP-1 + saline
- Where
- 2 sites in Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Overweight and Obesity
Satiety Innovation- Study 793. University of Aberdeen
The proposed study will address the effect of developed novel food products through processing innovation on motivation to eat, biomarkers of satiety, nutrient bioavailability and gut health using in vivo studies and validating…
- Trial name
- SATIN (NCT01724411)
- Testing
- Resistant Starch type 3
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- P Burns
Personal History of a Recent Suicidal Crisis, Suicidal Ideation
SmartCriseS - Smartphone Survey of Suicidal Risk
Sleep and appetite disorders as well as social exclusion, have been linked to the emergence of suicidal ideation (SI) and suicide attempts.This study aims to evaluate the relationship between those factors and suicidal ideation…
- Conditions
- Personal History of a Recent Suicidal Crisis, Suicidal Ideation, Suicidal Behaviour
- Trial name
- SmartCriseS (NCT03720730)
- Testing
- EMA
- Where
- 2 sites in France, Spain
- Volunteers
- 1,044 people
- Sponsor
- University Hospital, Montpellier
Eating Behavior, Obesity
Gut Hormone LEAP2 in Metabolism and Eating Behaviour: Fixed Meal Testing
The goal of this interventional study is to measure the blood levels of the gut hormones LEAP2 and acyl ghrelin (AG), appetite and food intake after consuming liquid meals of different caloric sizes, in healthy adults with and…
- Conditions
- Eating Behavior, Obesity, Appetitive Behavior
- Trial name
- LEAP2-meal (NCT06013592)
- Testing
- 0 kcal liquid meal, 600 kcal liquid meal, 900 kcal liquid meal (only for group without obesity)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cancer, Anorexia
Orexigenic Therapy With Delta-9-tetrahydrocannabinol in Advanced Cancer Patients With Chemosensory Abnormalities - a Pilot Study
To investigate delta-9-tetrahydrocannabinol's (THC) ability to increase food intake and improve food enjoyment for advanced cancer patients with taste and/or smell (chemosensory) abnormalities.
- Conditions
- Cancer, Anorexia, Taste Disorders, Olfactory Disorders
- Trial name
- NCT00316563
- Testing
- Marinol (Dronabinol)
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Alberta Health services
Cardiovascular Risk Factor
The Acute Effects of Meals Rich in Saturated or Unsaturated Fatty Acids on Postprandial Lipaemia in Healthy Men
Current dietary recommendations suggest that lowering intake of saturated fats or replacing it with unsaturated fats will decrease the risk of developing cardiovascular disease.
- Trial name
- CocoHeart (NCT05264233)
- Testing
- Coconut oil, Butter, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Reading
Focus of Study: Appetite
Effect of Protein From Animal and Vegetable Sources on Appetite
New Nordic diet guidelines advocate a reduction in consumption of protein from animal sources such as beef and pork, due to environmental concerns.
- Trial name
- PAVA (NCT01345487)
- Testing
- Vegetable Protein, Animal protein
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Arne Astrup
Migraine Disorders, Obesity
A Pilot Study of Migraine and Appetite Behaviour in Children
The purpose of this study is to determine whether there is an association between migraine in children and certain patterns of appetite or eating behaviour that may lead to later obesity.
- Trial name
- NCT00930852
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Cancer, Cachexia
Neurobehavioural and Cognitive Changes in Cancer Cachexia (CANCOG)
The goal of this observational study is to to look for changes within the brain, and changes in body-to-brain signals in people with cancer and people who do not have cancer. The main questions it aims to answer are: 1.
- Conditions
- Cancer, Cachexia, Cachexia-Anorexia Syndrome, Appetite Loss
- Trial name
- CANCOG (NCT06112964)
- Testing
- MRI/ Functional MRI, Self-reported questionnaires, Computer based tasks
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Appetitive Behavior
Appetite Variability
This study will examine appetitive sensation variability and the relationship between appetitive sensations and energy intake. Investigators believe the methods for assessing and interpretation of appetitive sensations are…
- Trial name
- NCT04836416
- Testing
- Observational
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
Effects of Learning and Food Form on Intake in Humans
Due to the rising incidence of obesity, much emphasis has been placed on identifying mechanisms of increased energy intake. At this point, the mechanisms responsible for the recent increase in obesity prevalence have not been…
- Trial name
- NCT01490034
- Testing
- Metabolic effects of consuming energy dense beverages, energy dense solid food, Energy dilute beverages
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Purdue University
Healthy Adult Male, Appetite
Effects of Cold-Water and Cold-Air Exercise on Appetite, Energy Intake, and Food Preference
This study investigated whether exercising in cold environments affects appetite, energy intake, and food preference compared with exercising in thermoneutral conditions.
- Conditions
- Healthy Adult Male, Appetite, Energy Intake
- Trial name
- NCT07681011
- Testing
- Control Condition, Cold-Water Exercise, Thermoneutral Water Exercise
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Coventry University
Astrocytoma, Brain Cancer
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
This is a multi-center, open-label, dose escalation study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of QBS10072S in patients with advanced or metastatic cancers…
- Conditions
- Astrocytoma, Brain Cancer, Brain Metastases, Bladder Cancer
- Trial name
- NCT04430842
- Testing
- QBS10072S
- Where
- 2 sites in Australia
- Volunteers
- 15 people
- Sponsor
- Quadriga Biosciences, Inc.
Postprandial Hyperglycemia
Bread Structure and Postprandial Metabolic Responses
The structural properties of bread are considered one of the most important factors that can affect its digestibility, glucose homeostasis and postprandial metabolic responses.
- Trial name
- NCT05691686
- Testing
- Finely milled whole wheat-legume bread, Less processed whole wheat-legume bread, Less processed whole wheat bread
- Where
- Greece
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Healthy Obesity, Metabolically, Obesity
Determining the Physiological Mechanisms Behind the ObeEnd Device on Factors Regulating Appetite
In Canada, over 60% of adults are classified as overweight and obese resulting in a public health crisis including increasing health care costs and negatively impacting the well-being of many Canadians.
- Trial name
- NCT06411483
- Testing
- ObeEnd Band
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal