Clinical trials: Appendicitis
Appendicitis, Postoperative Pain
Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block
This study is being conducted to compare two types of pain management techniques in patients undergoing open appendectomy (surgical removal of the appendix through a traditional incision).
- Trial name
- NCT06943456
- Testing
- Transversus Abdominis Plane (TAP) Block for Postoperative Pain Management, Standard Open Appendectomy with Postoperative Pain Management
- Volunteers
- 136 people
- Sponsor
- University of Health Sciences Lahore
Appendicitis Acute
Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold Standard.
This study is a retrospective evaluation of all patients treated surgically for appendicitis over a period of 3 years at the Sint- Andries Hospital, Tielt. Belgium.
- Trial name
- NCT05070000
- Testing
- Radiologic examination
- Volunteers
- 304 people
- Sponsor
- KU Leuven
Appendicitis
Nebulized Analgesia for Laparoscopic Appendectomy Trial
The objective of this study is to assess whether the administration of nebulized intra-peritoneal ropivacaine at the onset of surgery, compared with nebulized saline, reduces morphine consumption after laparoscopic appendectomy…
- Trial name
- NALA (NCT02624089)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Appendicitis
Low vs. Standard Dose CT for Appendicitis Trial
To determine whether low-dose (LD) CT is noninferior to standard-dose (SD) computed tomography (CT) as the first-line imaging test in adolescents and young adults in regard to negative appendectomy rate (NAR).
- Trial name
- LOCAT (NCT01925014)
- Testing
- Diagnostic CT with low-dose radiation, Diagnostic CT with standard-dose radiation
- Where
- 20 sites in South Korea
- Volunteers
- 3,074 people
- Sponsor
- Kyoung Ho Lee, MD
Parkinson's Disease, Chronic Appendicitis
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients.
- Conditions
- Parkinson's Disease, Chronic Appendicitis, Acupuncture
- Trial name
- NCT06304285
- Testing
- Acupuncture treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Acute Appendicitis, Acute Appendicitis With Rupture
Validation and Comparison of the Appendicitis Inflammatory Response Score and Adult Appendicitis Score
Acute appendicitis is one of the most frequent reasons of emergency laparotomy in adults. Symptoms of acute appendicitis overlap with other clinical conditions and might present as a challenge, especially in the early phases.
- Trial name
- NCT04730752
- Testing
- Appendicitis Inflammatory Response, Adult Appendicitis Score
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Nigde Omer Halisdemir University
Appendicitis
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
The purpose of this study is to demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
- Trial name
- CASA RELAX (NCT05966454)
- Testing
- Multiple standard of care antibiotics for appendicitis, at physicians' discretion
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Francisco
Acute Appendicitis
Laparoscopic Versus Open Appendectomy
Comparison of open and laparoscopic appendectomy
- Trial name
- NCT01967745
- Testing
- laparoscopic appendectomy, open appendectomy
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Varazdin General Hospital
Acute Appendicitis
IA Model for Acute Appendicitis in CT
the investigators's study group has developed a fully automated 3D convolutional neural network (CNN)-based diagnostic framework using information of appendix (IA) model to identify non-appendicitis and simple and complicated…
- Trial name
- NCT06175169
- Testing
- Information of Appendix (IA) model
- Where
- South Korea
- Volunteers
- 568 people
- Sponsor
- Hallym University Medical Center
Complicated Appendicitis, Intra-Abdominal Abscess
Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated Appendicitis
Appendicitis is one of the most common causes of acute surgical admission. Presently, two types of appendicitis are distinguished: complicated and uncomplicated (phlegmonous).
- Trial name
- ALPACA (NCT06841003)
- Testing
- Laparoscopic antibiotic peritoneal lavage with gentamicin / clindamycin
- Where
- 11 sites in Netherlands
- Volunteers
- 752 people
- Sponsor
- Spaarne Gasthuis
Appendicitis Acute, Laparoscopic Surgery
Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy
In this randomized control trial the patients with acute appendicitis will be divided in three groups according to the management of the appendiceal stump(Endostapler, Endoloop or Endoclip).
- Trial name
- NCT04083313
- Testing
- Technique used for closing the appendiceal stump
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- University Hospital Dubrava
Appendicitis
Antimicrobial Stewardship in Pediatric Surgery
Acute appendicitis is a common surgical emergency in children. Non-perforated appendicitis patients do not require antibiotics after appendectomy.
- Trial name
- AbxPS (NCT02270996)
- Testing
- Antimicrobial Stewardship Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Diabetes, Appendicitis
Mapping the Human Appendix Using Single Cell Sequencing
The overall purpose of this study is to describe the cellular composition of the human appendix and its gene expression using scRNAseq and scATACseq methods.
- Conditions
- Diabetes, Appendicitis, Inflammatory Bowel Diseases
- Trial name
- APPATA (NCT05209061)
- Testing
- Biopsy
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Bispebjerg Hospital
Appendicitis
Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure
This a prospective study to compare between clipping and ligation of appendicular stump in laparoscopic appendectomies regarding ;technical feasibility , post operative complications as fecal fistula and economic consideration.
- Trial name
- NCT07115303
- Testing
- Laparoscopic Appendectomy with application of clips for stump closure, Laparoscopic Appendectomy with ligature for stump closure
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Appendicitis, Surgery
Serum Hyperbilirubinemia as an Early Predictive Factor for Complicated Appendicitis: Single Center Experience
Serum total bilirubin provides a practical guide to early assessment of suspected appendicitis, supporting faster and more proportionate decisions-earlier escalation when overall risk is high and safe observation when it is low.
- Trial name
- NCT07291882
- Testing
- Appendectomy
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Minia University