Clinical trials: Apnea, Obstructive
Obstructive Sleep Apnea (OSA)
Digital-supported Orofacial Myofunctional Therapy in OSA
This pilot study explores the feasibility, acceptability, and preliminary effectiveness of Digital-supported Orofacial Myofunctional Therapy (d-MFT), an innovative program combining facial recognition technology with…
- Trial name
- NCT07292922
- Testing
- Digital-supported Orofacial Myofunctional Therapy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Metropolitan University
Respiratory Diseases
Oxidative Damage and Antioxidant Mechanisms in COPD
The environmental pollutants and endogenous reactive oxygen metabolites from inflammatory cells exert substantial pathological effects on the lung cells [1].
- Trial name
- NCT02406053
- Testing
- oxidative and antioxidant biomarkers
- Volunteers
- 111 people
- Sponsor
- Yuzuncu Yil University
Sleep Apnea, Obstructive, Pediatric Obesity
Obstructive Sleep Apnea in Obese Children and Teenagers - Occurrence and Importance of Intervention
The prevalence of childhood obesity has increased at an alarming rate over the last decades, both globally and in Denmark. There are a number of serious sequelae related to obesity, such as hypertension, hypercholesterolemia…
- Trial name
- NCT02463201
- Testing
- Weight loss
- Where
- 2 sites in Denmark
- Volunteers
- 236 people
- Sponsor
- Zealand University Hospital
Sleep Apnea Syndrome
Management of Patients With Suspected of Sleep Apnea-hypopnea Syndrome From Primary Care
Obstructive sleep apnea syndrome (OSA) is characterized by the manifestation of excessive sleepiness secondary to repeated obstruction of the upper airway during sleep and cognitive-behavioral, respiratory, cardiac, metabolic or…
- Trial name
- GESAP (NCT02234765)
- Testing
- Primary Care-based management, Standard management
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obstructive Sleep Apnea
Sedation in Patients at Risk for Upper Airway Collapse
Overview of Protocol: Between Subject - Repeated Measures design will be used to assess the airway response of two groups of subjects under two different sedated conditions.
- Trial name
- NCT01045122
- Testing
- Propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester
Obstructive Sleep Apnea
Adherence to Health Coaching with Wearable Devices: Enhancing Patient Engagement and Outcomes
The goal of this clinical trial is to learn how integrating health and wellness coaching (HWC) with Continuous Positive Airway Pressure (CPAP) therapy affects adherence to treatment and overall health outcomes in individuals with…
- Trial name
- NCT06525337
- Testing
- STANDARDCARE (STAND) group, CONTROL (CON) group
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Coastal Carolina University
OSA
Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases
The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as Overlap Syndrome (OS). The coexistence of these diseases have cardiovascular morbidity and mortality.
- Trial name
- NCT04903639
- Testing
- sleep study
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Obstructive Sleep Apnea, Atrial Fibrillation
Effective Conversion of Individuals at Risk
This study aims to guide participants in recognizing their OSA (obstructive sleep apnea) and AFib (atrial fibrillation) symptoms, realizing what medical conditions can cause these symptoms (if any) and inform the participants on…
- Trial name
- NCT05112757
- Testing
- Smartphone application use
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Obstructive Sleep Apnea Syndrome
Safety and Efficacy of Eszopiclone With Mild to Moderate Obstructive Sleep Apnea Syndrome (OSAS)
The purpose of this study is to evaluate the hypnotic efficacy of ezopiclone in subjects with mild to moderate OSAS.
- Trial name
- NCT00685269
- Testing
- Eszopiclone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Sumitomo Pharma America, Inc.
Sleep Apnea, Obstructive, Obesity
Life-style Changes in Obstructive Sleep Apnea
The primary aim is to study whether a tailored behavioural medicine intervention addressing physical activity and eating habits have additional effects to continuous positive airways pressure (CPAP) in patients with moderate or…
- Trial name
- NCT01102920
- Testing
- Behavioural strategies to promote physical activity and weight loss, CPAP
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
Dextrose Prolotherapy Versus LLLT in Treatment of Obstructive Sleep Apnea
This study was conducted on 26 patients with obstructive sleep apnea. The patients were divided randomly and equally into two equal groups.
- Trial name
- NCT06427161
- Testing
- LLLT application, dextrose injection
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Mansoura University
Sleep Apnea, Obstructive
Minimally Invasive Hypoglossal Nerve Stimulation Study (Lingual Study)
The purpose of this study is to assess the effect of Transvenous Hypoglossal Nerve Stimulation (tHGNS) on tongue position in the upper airway.
- Trial name
- Lingual (NCT03210142)
- Testing
- Transvenous hypoglossal nerve stimulation
- Where
- 3 sites in Hong Kong
- Volunteers
- 23 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Obstructive Sleep Apnea
TheraPAP Equivalence Crossover Study
The present study, TheraEquivalence, is a Phase 2 crossover study designed to examine the efficacy and safety of TheraPAP (TPAP) vs. CPAP alone in the treatment of OSA.
- Trial name
- NCT06238362
- Testing
- TPAP, CPAP
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- SleepRes Inc.
Obstructive Sleep Apnea Syndrome
Telemedicine to Enhance Adherence to CPAP Therapy in Patients With OSAS
We hypothesize that the use of telemedicine combined with support interventions by short messages, telephone calls and ambulatory visits to control CPAP treatment during the first month improves adherence and reduces unresolved…
- Trial name
- NCT01715194
- Testing
- Telemedicine intervention
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Otto D. Schoch
Obstructive Sleep Apnea, Obesity
Effect of Nasal Positive Airway Pressure Versus Standard Care on Oxygenation and Ventilation During Propofol-based Sedation for Colonoscopy in Patients With High Risk of Airway Obstruction
The purpose of this study is to to compare oxygenation and ventilation on spontaneously ventilating obese patients or those with diagnosed or undiagnosed Obstructive sleep apnea (OSA) undergoing day colonoscopy under Propofol…
- Trial name
- NCT05524220
- Testing
- Standard care with a facemask., SuperNO2VA™EtCO2 (Nasal Oxygenating Ventilating Apparatus)
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obstructive Sleep Apnea, Type 2 Diabetes
Neck Grasp as a Predictor of Sleep Apnea
A previous pilot study on the use of self neck grasp, ESAP (Easy Sleep Apnea Predictor), showed a positive maneuver (unable to wrap hands completely around neck) to be 100% predictive of sleep apnea in a sleep clinic population.
- Trial name
- NCT02474823
- Testing
- polysomnogram, home sleep test, Easy Sleep Apnea Predictor
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Bassett Healthcare
Sleep Apnea, Obstructive
Portable Monitoring for Diagnosis and Management of Sleep Apnea
This multi-site project compares compares the efficiency of a home-based portable monitoring strategy to a standard of care sleep laboratory-based strategy for the diagnosis and positive airway pressure treatment of obstructive…
- Trial name
- HomePAP (NCT00642486)
- Testing
- Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex), Standard polysomnography (PSG)
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Case Western Reserve University
Pediatric Obstructive Sleep Apnea
The Use of Psychomotor Vigilance Testing in the Assessment of Pediatric Obstructive Sleep Apnea
Obstructive sleep apnea results in decreased attentiveness and response times in patients. The objective of this study is to quantify these consequences in pediatric OSA patients using an already established tool for examining…
- Trial name
- PVT (NCT01276860)
- Testing
- Psychomotor Vigilance Testing
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Early Warning System
The study will begin in 2013 whereby patients having an early warning system (EWS) alert will be randomized to be seen by the rapid response team (RRT) for triage versus usual care.
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cancer, Diabetes Mellitus
- Trial name
- NCT01741480
- Testing
- Early warning system monitoring., routine care
- Where
- United States
- Volunteers
- 571 people
- Sponsor
- Washington University School of Medicine
Normal Tension Glaucoma, Obstructive Sleep Apnea
Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness
The purpose of this research study is to learn more about the relationship between Obstructive Sleep Apnea (OSA) and Normal Tension Glaucoma (NTG).
- Trial name
- NCT06023927
- Testing
- Clinical observation, diagnostic testing
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health