Clinical trials: Aphasia, Acquired
Aphasia, Acquired, Chronic Stroke
VR and Scrip Training of PWA, Randomized Controlled Trial
The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes.
- Trial name
- VRSTPWA (NCT06722092)
- Testing
- VR-based script training, Conventional script training
- Volunteers
- 105 people
- Sponsor
- The Hong Kong Polytechnic University
Aphasia, CVA
Treatment Intensity - Apraxia of Speech
A growing neurorehabilitation literature suggests that intense treatment may be desired to maximize the effects of therapy following neurologic injury.
- Conditions
- Aphasia, CVA, Apraxia of Speech
- Trial name
- NCT02332915
- Testing
- Sound Production Treatment (SPT)
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Aphasia, Apraxia of Speech
Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech
The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural…
- Conditions
- Aphasia, Apraxia of Speech, Dysarthria
- Trial name
- NCT04604444
- Testing
- Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Aphasia, Acquired, Language Disorders
Enhancing Language Function in Aphasia
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain).
- Conditions
- Aphasia, Acquired, Language Disorders, Primary Progressive Aphasia, Stroke, Cerebrovascular
- Trial name
- NCT05443633
- Testing
- individualized speech-language training, standard language intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Aphasia, Aphasia Following Cerebral Infarction
Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)
The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired…
- Conditions
- Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation
- Trial name
- NCT07036406
- Testing
- Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Teachers College, Columbia University
Aphasia, Acquired, Short-Term Memory Impairment
Short-term Memory Assessment in Patients With Poststroke Aphasia
Background and aim There is a growing awareness that people with aphasia (language problems) after a stroke often have difficulties with their short-term memory (STM).
- Trial name
- NCT06068296
- Testing
- short term memory assessment, Oxford cognitive screen, Token Test
- Where
- 2 sites in Belgium
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Aphasia, Acquired
Speech Entrainment Treatment for People With Aphasia
The objective of this research is to experimentally delineate the direct effect of speech entrainment practice on independent speech production and identify practice conditions that enhance treatment benefits.
- Trial name
- NCT05687994
- Testing
- Audiovisual Speech Entrainment Practice, Auditory Speech Entrainment Practice
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Albert Einstein Healthcare Network
Aphasia, Stroke
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke.
- Conditions
- Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
- Trial name
- TMS (NCT06842745)
- Testing
- Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Aphasia, Acquired, Aphasia
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
The goal of this clinical trial is to establish the feasibility and fidelity of a high-intensity exercise program for individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent
- Trial name
- NCT06185023
- Testing
- Low-intensity physical exercise, High-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of California, Berkeley
Aphasia, Acquired, Stroke, Acute
Neolexon® Aphasia-App in Acute Aphasia After Stroke
Up to now there is proven evidence of traditional logopedic therapy in aphasia, but recent computer-based algorithms also showed their evidence so far.
- Trial name
- Lexi (NCT04080817)
- Testing
- Neolexon, Speech therapy, Self training
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Dyslexia, Acquired, Brain Injuries
Therapy for Reading Problems in Adults After Brain Injury
Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
- Conditions
- Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
- Trial name
- NCT00064805
- Testing
- Cognitive Therapy to Improve Reading
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Aphasia, Stroke
Dosage and Predictors of Naming Treatment Response in Aphasia
This study examines aphasia treatment response among Veterans and non-Veterans living with aphasia. It seeks to identify cognitive and neural factors which are predictive of positive response to treatment targeting naming…
- Trial name
- NCT02005016
- Testing
- Naming therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Aphasia, Acquired, Aphasia Primary Progressive
Spaced Retrieval as Treatment for Aphasia
Spaced Repetition training has been found to be more effective than massed repetition for individuals with aphasia. This study seeks to examine the relative efficiency of three kinds of spacing for picture-naming training…
- Trial name
- NCT04623125
- Testing
- Spaced Retrieval Practice
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Rotman Research Institute at Baycrest
Apraxia of Speech, Aphasia, Acquired
Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)
The purpose of the proposed research is to examine the effects of two treatment approaches on speech production involving speakers with chronic apraxia of speech (AOS) and aphasia.
- Conditions
- Apraxia of Speech, Aphasia, Acquired, Speech Disorders
- Trial name
- EPG&SPT (NCT02554513)
- Testing
- EPG Tx, SPT
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Aphasia, Acquired
Efficacy of a Combined Linguistic/Communication Therapy in Acute Aphasia After Stroke
Linguistic training is traditionally the gold standard for rehabilitation of aphasia after stroke and efficacy criteria count early stage, intensity as well as personalized treatment.
- Trial name
- ORACLE (NCT03287544)
- Testing
- Combined rehabilitation, Linguistic rehabilitation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Toulouse
Aphasia, Acquired
Effects of rTMS on Brain Activation in Aphasia
This study will investigate the use of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation method, to improve word-finding abilities in Veterans and non-Veterans with chronic language problems…
- Trial name
- NCT03292471
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Consciousness Disorders, Severe Acquired Brain Injury
Cross-cultural Adaptation and Multicenter Validation of the Italian Versions of the Brief Evaluation of Receptive Aphasia (BERA) and SWallowing Assessment in Disorders of Consciousness (SWADOC)
Patients with severe acquired brain injury may evolve from coma into prolonged disorders of consciousness. In these patients, residual language comprehension and swallowing abilities are difficult to evaluate because standard…
- Trial name
- NCT07711119
- Testing
- Italian SWallowing Assessment in Disorders of Consciousness (SWADOC), Italian Brief Evaluation of Receptive Aphasia (BERA)
- Where
- 4 sites in Italy
- Volunteers
- 79 people
- Sponsor
- Alfonso Magliacano
Aphasia, Acquired, Speech Therapy
Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: Pilot Study of Multidimensional Effects
The goal of this clinical trial is to measure the effects of a speech therapy protocol combining anomia therapy and executive function training on naming and discourse in people with chronic aphasia, and to study the related…
- Trial name
- ATAC2PILOT (NCT06712225)
- Testing
- Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Aphasia, Acquired
Virtual Reality in Aphasia Telerehabilitation
The main purpose of this study is to evaluate the use of the immersive 3D HMD VR technology in the language intervention with a home-based telerehabilitation approach for people with aphasia.
- Trial name
- NCT04828759
- Testing
- VR-treatment, Treatment as usual
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Aphasia, Traumatic Brain Injury
Narrative Comprehension by People With Acquired Brain Injury
The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only…
- Trial name
- NCT03309930
- Testing
- Comprehension Acquired Brain Injury
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Miami University