Clinical trials: Aortic Dissection Type B
Type A Aortic Dissection
European Registry of Type A Aortic Dissection
Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity.
- Trial name
- ERTAAD (NCT04831073)
- Testing
- Surgery on the ascending aorta with or without repair of the aortic root and/or aortic arch
- Where
- 20 sites in Belgium, Czechia and 6 more
- Volunteers
- 3,902 people
- Sponsor
- Helsinki University Central Hospital
Type A Aortic Dissection, Complication of Surgical Procedure
Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection Surgery
This is a national, multicenter, open-label, randomized, controlled, endpoint-blinded clinical trial of patients diagnosed with ATAAD and undergoing "Sun's procedure" coordinated by the First Affiliated Hospital of Xi'an Jiaotong…
- Conditions
- Type A Aortic Dissection, Complication of Surgical Procedure, Aortic Diseases
- Trial name
- ADVANCED-XJ-Ⅱ (NCT06199401)
- Testing
- Vascular Grafts Eversion and Built-in Technique(XJ-Procedure)
- Where
- China
- Volunteers
- 680 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Type A Aortic Dissection
Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD
Acute Type A Aortic Dissection (ATAAD) is a serious medical condition that requires immediate surgical intervention. The repair of Acute Type A Aortic Dissection (ATAAD) combines different surgical procedures, including the use…
- Trial name
- NCT06434987
- Testing
- Retrograde Inferior Vena Cava Perfusion, Antegrade cerebral perfusion
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Type B Aortic Dissection, Return to Work
Patients With Type B Aortic Dissection Returning to Work After Discharge：a Cross-sectional Survey
This study wants to understand the incidence of returning to work after discharge in patients with type B aortic dissection.
- Trial name
- NCT06418828
- Testing
- return to work
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Fujian Medical University Union Hospital
Nomogram, Prediction Model
Prediction Models for Postoperative Reintubation in Patients With Acute Aortic Dissection
Reintubation is an adverse postoperative complication in patients with Type A aortic dissection (AAD) that correlates to poor outcomes.
- Conditions
- Nomogram, Prediction Model, Type A Aortic Dissection, Postoperative Reintubation
- Trial name
- ADreintubate (NCT06415630)
- Testing
- Type A aortic dissection surgery
- Where
- China
- Volunteers
- 861 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Penetrating Ulcer of Aorta, Aneurysm Aortic
Evaluation of the Valiant Captivia Physician Fenestrated Stent Graft System in Aortic Arch and Descending Thoracic Aorta Pathologies
The study objectives are to assess safety and effectiveness, measured acutely and at the 30-day visit after implantation of the Valiant Captivia physician fenestrated Stent Graft.
- Conditions
- Penetrating Ulcer of Aorta, Aneurysm Aortic, Type B Aortic Dissection, Residual Dissection After Type A Repair
- Trial name
- EVERGREEN (NCT05479305)
- Testing
- The Valiant Captivia Stent Graft
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Ceric Sàrl
Type B Aortic Dissection
Guo's Subclavian Artery Reconstruction: The Prospective, Multiple Center Study of WeFlow-Tbranch Stent Graft System(GUEST Study)
This study is a prospective, multiple center study to evaluate the safety and effectiveness of WeFlow-Tbranch single embedded branch thoracic aorta stent graft system manufactured by EndoNom Medtech (Hangzhou) Co., Ltd.
- Trial name
- NCT04765605
- Testing
- WeFlow-Tbranch Stent Graft System
- Where
- 29 sites in China
- Volunteers
- 120 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Type B Aortic Dissection
Aortic Remodeling After Endovascular Management of Type B Aortic Dissection.
Assess the clinical outcome, morphological changes and behaviour of type B aortic dissection after endovascular repair.
- Trial name
- NCT06289777
- Testing
- TEVAR
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Aortic Dissection Type B
Dragon Study Europe
Dragon Study Europe is an international, multicenter, prospective, non-randomized study. It is designed to evaluate safety and performance of the MFM for the treatment of chronic type B aortic dissection.
- Trial name
- NCT03033771
- Testing
- Implantation with the Multilayer Flow Modulator (MFM)
- Where
- 4 sites in Bulgaria, Romania
- Volunteers
- 27 people
- Sponsor
- Cardiatis
Type A Aortic Dissection
Safety and Efficacy of Aortic Root Reinforcement Combined With Vascular Grafts Eversion and built-in Procedure (XJ-procedure) in Patients With Acute Type A Aortic Dissection (ADVANCED-XJ )
This is a retrospective study based on the data available in our hospital database for ATAAD patients from January 2020 to December 2021.
- Trial name
- NCT05751200
- Testing
- No Intervention.
- Where
- China
- Volunteers
- 183 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Chronic Stanford B Type Aortic Dissection Proximal Tear
Guo's Entry Tear Repair :The First in Man Study of Endopatch System
A prospective, single-center, first in man study to evaluate the safety and efficacy of Endopatch System manufactured by Hangzhou Endonom Medtech Co., Ltd. for the Chronic Stanford B type aortic dissection proximal tear.
- Trial name
- NCT04745039
- Testing
- Endopatch System
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Methylprednisolone, Thoracic Endovascular Repair
PreOperative Methylprednisolone on Thoracic Endovascular Repair for Reducing Post-implantation Syndrome (POMTEVAR)
POMTEVAR trial is a multicenter, open-label and prospective random controlled study. Approximately 158 patients will be randomly allocated to thoracic endovascular repair (TEVAR) alone group or TEVAR plus methylprednisolone group…
- Conditions
- Methylprednisolone, Thoracic Endovascular Repair, Post-implantation Syndrome, Type B Aortic Dissection
- Trial name
- NCT05349071
- Testing
- methylprednisolone, physiological saline
- Volunteers
- 158 people
- Sponsor
- Guangdong Provincial People's Hospital
Type A Aortic Dissection
Surgical Management of the Aortic Root and Long-term Outcomes For Acute Type A Aortic Dissection
The investigators focus on the patients who underwent aortic root surgery for acute type A aortic dissection between 2005.01-2021.11.
- Trial name
- NCT05346497
- Testing
- Bentall, David, ARR
- Volunteers
- 1,600 people
- Sponsor
- Shanghai Zhongshan Hospital
Distal Aortic Dissection, Dissection, Aortic Acute
ACute Uncomplicated Type b Aortic Dissection: Endovascular Repair vs. Best Medical Therapy
The purpose of the study is to conduct a randomized controlled trial comparing best medical therapy (BMT) alone to BMT with thoracic endovascular aortic repair (BMT+TEVAR) for uncomplicated acute type B aortic dissection.
- Conditions
- Distal Aortic Dissection, Dissection, Aortic Acute, Acute Type B Aortic Dissection (Uncomplicated)
- Trial name
- ACUTE-B (NCT02622542)
- Testing
- BMT+TEVAR, BMT
- Where
- 2 sites in United States
- Volunteers
- 436 people
- Sponsor
- The University of Texas Health Science Center, Houston
Aortic Dissection Type B
Safety and Efficacy Study of Fabulous Stent Graft System for Stanford B Aortic Dissection
A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of Fabulous Stent Graft System manufactured by Hangzhou Endonom Medtech Co., Ltd. for Stanford B Aortic Dissection.
- Trial name
- NCT04918212
- Testing
- Fabulous Stent Graft System
- Where
- 24 sites in China
- Volunteers
- 148 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Type A Aortic Dissection
BioGlue as an Adjunct for Structural Repair and Hemostasis in Chinese Acute Type A Aortic Dissections Patients
A multi-center, randomized, controlled clinical trial is designed to investigate the safety and efficacy of BioGlue as an adjunct for structural repair and hemostasis to traditional surgical repair in Chinese subject with Acute…
- Trial name
- CHINA (NCT03369977)
- Testing
- BioGlue Surgical Adhesive, Traditional Surgical Repair
- Where
- 7 sites in China
- Volunteers
- 202 people
- Sponsor
- CryoLife, Inc.
Acute Type A Aortic Dissection With Arch Involvement, Cardiopulmonary Bypass
Hemoperfusion in Acute Type A Aortic Dissection Patients Undergoing Aortic Arch Operation (HPAO)
This study is a single-center, randomized, controlled, double-blind clinical trial. The main purpose of this study is to evaluate if hemoperfusion is sufficient to improve the prognosis of acute type A aortic dissection patients…
- Conditions
- Acute Type A Aortic Dissection With Arch Involvement, Cardiopulmonary Bypass, Deep Hypothermic Circulatory Arrest
- Trial name
- HPAO (NCT04007484)
- Testing
- Hemoperfusion
- Where
- China
- Volunteers
- 88 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Type A Aortic Dissection
iNO as Salvage Treatment of Hypoxemia After TAAD Surgery
The purpose of this study was to clarify the possible mechanism of hypoxemia after surgical treatment of type A acute aortic dissection and the possible mechanism of the treatment role of inhaled nitric oxide in refractory…
- Trial name
- NCT04032366
- Testing
- inhaled nitric oxide, PEEP
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Chest Pain, Acute Aortic Dissection
Prospective Multicenter Study for Early Evaluation of Acute Chest Pain
In this study, clinical database and blood sample bank of acute chest pain (ACP) will be established at chest pain center of multi-center hospital.
- Conditions
- Chest Pain, Acute Aortic Dissection, Pulmonary Embolism, Acute Myocardial Infarction Type 1
- Trial name
- PEACP (NCT04122573)
- Testing
- Coronary angiography, CT angiography of aorta, CT angiography of pulmonary arteries.
- Where
- 9 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Type A Aortic Dissection, Circulatory Arrest
Antegrade Cerebral Perfusion and Retrograde Inferior Vena Caval Perfusion for Total Aortic Arch Replacement
This study is designed as a multicenter, randomized, assessor- blinded clinical trial.The primary aim of this trial is to assess whether retrograde inferior venal caval perfusion combined selective antegrade cerebral…
- Conditions
- Type A Aortic Dissection, Circulatory Arrest, Hypothermia
- Trial name
- CARTAR (NCT03607786)
- Testing
- Retrograde Inferior Vena Caval Perfusion, Select antegrade cerebral perfusion
- Where
- China
- Volunteers
- 600 people
- Sponsor
- West China Hospital