Clinical trials: Anxiety Sensitivity, active
Child Allergy, Anxiety
Using a Stress Ball on Fear, Anxiety, Pain, and Satisfaction During Allergy Testing
This randomized controlled trial aims to evaluate and compare the effects of watching cartoons and using a stress ball on levels of fear, anxiety, pain, and satisfaction among 90 children aged 4-10 undergoing skin prick testing…
- Conditions
- Child Allergy, Anxiety, Fear, Pain
- Trial name
- NCT07750236
- Testing
- cartoon-watching group, stress ball group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Tarsus University
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children
This study aims to compare the effectiveness of intraosseous and infiltration anesthesia techniques administered using a computer-assisted anesthesia device (SleeperOne® 5; Dental HiTec, France) during restorative treatments of…
- Trial name
- MIH (NCT07352813)
- Testing
- Intraosseous anaesthesia using a computerized system, Infiltration anaesthesia using a computerized system
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Perinatal Anxiety, Anxiety Sensitivity
Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders
The goal of this clinical trial is to find out if a digital program called Reaching Calm can help prevent anxiety in women who are pregnant.
- Conditions
- Perinatal Anxiety, Anxiety Sensitivity, Perinatal Depression
- Trial name
- NCT07458698
- Testing
- Digital mental health intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Generalized Anxiety Disorder, Oxygenation Sensitive CMR
BreathinG-induced Myocardial and Cerebral Perfusion in Anxiety Disorders
This study aims to view variations in MRI measurements of the heart and the brain in people with anxiety versus healthy volunteers.
- Trial name
- B-GLAD (NCT05574140)
- Testing
- Cardiac MRI
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
ESCAPE Intervention+NRT, quitSTART Intervention+NRT
Enhancing Smoking Cessation for African American People Everywhere
The present study aims to investigate the efficacy of an mHealth smoking cessation and HIV disease management intervention among a nationally representative sample of African America/Black (hereafter refer to as Black) persons…
- Conditions
- ESCAPE Intervention+NRT, quitSTART Intervention+NRT, CTRL+NRT
- Trial name
- ESCAPE (NCT07024992)
- Testing
- ESCAPE app + NRT, quiSTART app + NRT, Control (CTRL)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Houston
Sarcoidosis, Fatigue
Virtual Patient Groups for Sarcoidosis Associated Fatigue
This research study is testing whether Mindfulness-Based Stress Reduction (MBSR) can help reduce fatigue in people with sarcoidosis. The study will also look at whether MBSR can improve symptoms of anxiety and depression.
- Conditions
- Sarcoidosis, Fatigue, Depression, Anxiety
- Trial name
- SupportSarc (NCT07073963)
- Testing
- Virtual Mindfulness Based Stress Reduction Group, Virtual sarcoidosis support group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Asthma
Remote Anxiety Management for ICS-resistant Asthma Study
This study, the Remote Anxiety Management for ICS-resistant Asthma Study (RAMICS), explores strategies to improve medication adherence and anxiety management in asthma patients who are resistant to using inhaled corticosteroids…
- Trial name
- RAMICS (NCT06732141)
- Testing
- Personalized Telephone-Based Psychological Support, Standard Care with Weekly Follow-Up Calls
- Where
- 11 sites in China
- Volunteers
- 216 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Fibromyalgia, Fibromyalgia Syndrome
Slow Breathing and Resistance Exercise in Fibromyalgia
This randomized controlled trial investigates whether slow breathing techniques influence heart rate variability, exercise self-efficacy, and resistance exercise performance in women with fibromyalgia.
- Trial name
- Breath-fibro (NCT07404384)
- Testing
- Slow Breathing with Visual Pacer, Slow Breathing without Visual Pacer, Spontaneous Breathing (Active Control)
- Where
- 2 sites in Spain
- Volunteers
- 159 people
- Sponsor
- University of Malaga
Anxiety/Depression and Asthma
The Impact of Anxiety/Depression on the Efficacy of Asthma Control Drugs and the Construction of a Predictive Model for the Risk of Acute Asthma Attacks
The goal of this clinical trial is to explore the impact of anxiety/depression on the efficacy of asthma controller medications and to develop a risk prediction model for asthma acute exacerbations in patients with asthma.
- Trial name
- NCT07679321
- Testing
- No intervention measures
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Xiangya Hospital of Central South University
Posttraumatic Stress Disorder, Cannabis Use Disorder
Mitigating PTSD-CUD After Sexual Assault
683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD).
- Trial name
- RISE-C (NCT05989841)
- Testing
- RISE Guide, Relaxation Control
- Where
- 6 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Nevada, Las Vegas
Asthma, Anxiety
Online Cognitive Behavior Therapy for Anxiety Related to Pediatric Asthma
Asthma is a chronic condition affecting approximately 5-15% of all Swedish children. Research has shown that asthma may be associated with increased anxiety and worry, with children who have asthma being twice as likely to…
- Trial name
- NCT06657807
- Testing
- Online CBT
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Exercise Sensitivity, Introceptive Exposure
Behavioral Exposure for Introceptive Tolerance RCT
Behavioral Exposure for Interoceptive Tolerance (BE-FIT) is a mechanism-informed behavioral intervention to target exercise anxiety.
- Conditions
- Exercise Sensitivity, Introceptive Exposure, Anxiety, Cardiac Rehabilitation
- Trial name
- BE-FIT (NCT05398276)
- Testing
- Behavioral Exposure For Introceptive Tolerance, Health Education Control
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rutgers, The State University of New Jersey
Prenatal Anxiety, Prenatal Depression
Increasing Physical Contact Between Prenatally Anxious/Depressed Mothers and Their Infants to Improve Maternal Sensitivity.
The goal of this randomized controlled pilot trial is to evaluate the feasibility, acceptability, and clinical utility of a baby carrier intervention aimed at improving maternal sensitivity and mother-infant bonding in prenatally…
- Conditions
- Prenatal Anxiety, Prenatal Depression, Maternal Sensitivity
- Trial name
- NCT06726304
- Testing
- Baby Carrier Intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Emotion Regulation Disorders
Virtual Reality Exposure Therapy for Emotion Regulation Difficulties in Adolescent Inpatients
The goal of this clinical trial is to evaluate whether a therapist-guided virtual reality (VR)-based intervention can improve emotion regulation in adolescents receiving inpatient psychiatric treatment.
- Trial name
- VRsafe (NCT07709468)
- Testing
- Virtual Reality Exposure Therapy
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
Cigarette Smoking, Smoking Cessation
Impacto 2.0: Mobile Smoking Cessation Across Texas
This is a preliminary efficacy trial that will examine whether Impacto 2.0 produces higher rates of biochemically verified smoking abstinence among Hispanic adults across Texas compared to the NCI quitSTART app.
- Trial name
- NCT07915973
- Testing
- Impacto 2.0, quitSTART
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Michael J. Zvolensky, Ph.D.
Hypotension, Cesarean Section
"Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section"
Spinal anesthesia-induced hypotension is one of the most frequent and clinically significant complications of obstetric anesthesia, occurring in up to 50-80% of parturients undergoing elective cesarean section.
- Conditions
- Hypotension, Cesarean Section, Hemodynamic Instability, Anxiety, Anticipatory
- Trial name
- BREATHE-CS (NCT07494955)
- Testing
- Mindfulness-Based Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Aysenur Dostbil
Nicotine Dependence
Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address the question - is a smoking cessation intervention personalized to high…
- Trial name
- STEP3 (NCT06053567)
- Testing
- Aerobic Exercise, Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Atopic Dermatitis, Pain
Virtual Reality for Pain Management During Dupilumab Injection
The aim of this within-subject randomized study is to examine the efficacy of a VR immersive game for pain and anxiety management of children during the subcutaneous injection of dupilumab for moderate to severe atopic…
- Conditions
- Atopic Dermatitis, Pain, Anxiety
- Trial name
- VR-DERMA (NCT06182436)
- Testing
- Virtual Reality Distraction, Standard Treatment
- Where
- 2 sites in Canada
- Volunteers
- 98 people
- Sponsor
- St. Justine's Hospital
Anxiety Disorders, Anxiety
Pramipexole to Enhance Social Connections
This study seeks to understand if the medication pramipexole improves social connectedness and functioning in adults (ages 18-50) who experience anxiety or depression.
- Conditions
- Anxiety Disorders, Anxiety, Depression, Social Disconnection
- Trial name
- NCT06269146
- Testing
- Pramipexole Pill
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Diego
Depression, Anxiety, Fear
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
This mechanistic study uses an anti anxiety drug and brain imaging to study the threat processing system and associated brain circuits in people with depression, anxiety disorders and comorbid depression and anxiety disorders.
- Conditions
- Depression, Anxiety, Fear, Depression, Anxiety and Fear
- Trial name
- NCT06004115
- Testing
- Lorazepam
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Laureate Institute for Brain Research, Inc.