Clinical trials: Antimicrobial Stewardship
Antimicrobial Stewardship
Evidence Based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU)
The goal of this observational study is to learn about the implementation of a process to review antimicrobial prescriptions for adult patients in Intensive Care Unit (ICU).
- Trial name
- EQUIPS-ICU (NCT06666738)
- Testing
- Structured antimicrobial review
- Where
- Vietnam
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Antimicrobial Stewardship, Antimicrobial Resistance (AMR)
A Digital Escape Room to Teach Veterinary Students About Antimicrobial Resistance Using the One Health Approach
The goal of this study is to evaluate the effectiveness of a One Health-based educational intervention in second-year medical students from the veterinary university in Norway The main question it aims to answer is: 1.
- Trial name
- NCT07864077
- Testing
- AMRageddon
- Where
- Norway
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Infection, Antimicrobial Stewardship Program
Molecular Microbiology- Guided Antimicrobial Stewardship Versus Standard Stewardship in Hospitalized Patients
The goal of this clinical trial is to learn whether integrating rapid multiplex molecular microbiology results with predefined clinical and laboratory criteria into an antimicrobial stewardship program improves antimicrobial use…
- Conditions
- Infection, Antimicrobial Stewardship Program, Antimicrobial Resistance, Multiplex PCR
- Trial name
- PROACT (NCT07684300)
- Testing
- Protocolized Antimicrobial Stewardship Strategy, Standard Antimicrobial Stewardship
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Maria Espinosa Perez
Community-Acquired Pneumonia, Antimicrobial Stewardship
Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia
The purpose of this study is to reduce the exposure of broad-spectrum antimicrobials by optimizing the rapid detection of CAP pathogens and improving rates of de-escalation following negative cultures.
- Conditions
- Community-Acquired Pneumonia, Antimicrobial Stewardship, Point-of-Care Testing
- Trial name
- NCT05568654
- Testing
- Rapid Diagnostic Testing, Pharmacist-led de-escalation
- Where
- 12 sites in United States
- Volunteers
- 28,580 people
- Sponsor
- The Cleveland Clinic
Otitis Media, Antimicrobial Stewardship
Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children
Randomized controlled trial involving 40 pediatric primary care clinicians with high rates of diagnosing and treating middle ear infections.
- Trial name
- NCT06731660
- Testing
- Education with personalized performance feedback, Use of digital otoscope
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Children's Hospital
Otitis Media, Antimicrobial Stewardship
Digital Otoscopy Versus Standard Otoscopy on the Diagnosis and Treatment of Otitis Media in Young Children
Randomized controlled trial involving 4 pediatric primary care practices in Massachusetts. Practices will be stratified by their OM diagnosis and treatment rate, with two practices randomly assigned to the intervention arm and…
- Trial name
- Wispr 2 (NCT07328555)
- Testing
- Device: Digital Otoscope
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boston Children's Hospital
The Use of Antimicrobial Stewardship in in General Practice (Family Medicine), Respiratory Tract Infections (RTI)
Optimal Implementation of Antimicrobial Stewardship in General Practice
This trial aims to increase the use of antimicrobial stewardship resources when treating patients with respiratory tract infections. This trial is set in Australian general practices (family medicine or primary care).
- Trial name
- OPTIMAS-GP (NCT06953804)
- Testing
- Antimicrobial stewardship activities delivered through Virtual Network, Antimicrobial stewardship activities delivered through Integrated Network activities
- Where
- 4 sites in Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Wollongong
Antimicrobial Stewardship, Antimicrobial Drug Resistance
Peer Comparison Feedback As An Antimicrobial Prescribing Intervention To General Medicine Specialists
The purpose of this study is to evaluate the effect of a peer comparison feedback report, combined with a best practices toolkit, on the volume of antimicrobial use by general medicine physicians.
- Trial name
- PEER AIMS (NCT07189364)
- Testing
- Peer Comparison Feedback Report
- Where
- Canada
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fahad Razak
Antimicrobial Stewardship Program, Resistance Bacterial
Antimicrobial Stewardship Program Implementation in Brazilian Public Hospitals (PeGASUS)
Antimicrobial resistance is a major global public health challenge, leading to increased morbidity, mortality, and healthcare costs.
- Trial name
- PeGASUS (NCT07514884)
- Testing
- ASP implementation
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Urinary Tract Infection(UTI), Antimicrobial Stewardship
Diagnostic Stewardship Intervention to Reduce Inappropriate Antibiotic Use for Urinary Tract Infections in Primary Care
Urine culture is the most common microbiological test in the outpatient setting in the United States. Unfortunately, contamination during collection is prevalent and undermines test accuracy, leading to incorrect diagnosis…
- Conditions
- Urinary Tract Infection(UTI), Antimicrobial Stewardship, Primary Care
- Trial name
- NCT07246837
- Testing
- MSCC Educational Tool
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Baylor College of Medicine
Infection, Antimicrobial Stewardship
Quality Improvement Intervention for a Safe Antimicrobial Use Reduction in Critically Ill Patients
The goal of this clinical trial is to learn if an educational intervention with audit and feedback on physicians and health care professionals who participate in antimicrobial treatment decisions can reduce the use of…
- Conditions
- Infection, Antimicrobial Stewardship, Critically Ill Intensive Care Unit Patients
- Trial name
- SAFE-REDUCE (NCT07093450)
- Testing
- Educational Quality Improvement Intervention
- Where
- 9 sites in Brazil
- Volunteers
- 9,000 people
- Sponsor
- Hospital Sirio-Libanes
Antimicrobial Stewardship, Drug Resistance, Bacterial
Optimising Community Antibiotic Use and Infection Control With Behavioural Interventions in Burkina Faso and DR Congo
Emergence of antibiotic resistance (AMR) is a serious concern for Low and Middle Income Countries (LMICs). Unregulated use of antibiotics, a major AMR driver, is highly prevalent in LMICs, with medicine stores as key providers.
- Trial name
- CABU-B/C (NCT05378880)
- Testing
- Behavioural intervention bundle to optimise antibiotic use and reduce the risk of human-to-human or environmental-animal-human transmission
- Where
- 2 sites in Burkina Faso, Democratic Republic of the Congo
- Volunteers
- 5,532 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Bacteremia, Antimicrobial Stewardship
Knowledge Attitude and Practice Regarding Bloodstream Bacterial Infections and Antibiotics Usage Among Doctors.
This study is designed to use a questionnaire to assess doctors' knowledge, attitudes, and practices regarding bloodstream bacterial infections and antibiotic use in Tawam and Al Ain tertiary Hospitals (both hospitals have the…
- Conditions
- Bacteremia, Antimicrobial Stewardship, Antibiotic Use, Antibiotic Abuse
- Trial name
- NCT06605677
- Testing
- Questionnaire
- Where
- United Arab Emirates
- Volunteers
- 100 people
- Sponsor
- Abu Dhabi Health Services Company
Antimicrobial Stewardship, Cost-effectiveness Analysis
Cost-effectiveness Analysis of an Antimicrobial Stewardship Program in Regione Lombardia (RF-net2018)
Cost-effectiveness analysis of an Antimicrobial Stewardship program in Regione Lombardia: "RF-net2018" is a prospective, experimental, multicenter, pre-post study, whose objectives are the evaluation of the efficiency of economic…
- Trial name
- RF-net2018 (NCT06388278)
- Where
- Italy
- Volunteers
- 50,000 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Antimicrobial Stewardship, Acute Bronchitis
Using Behavioral Science to Reduce Inappropriate Antibiotic Use in Acute Care Settings
Stepped wedge behavioral intervention clinical trial looking at the impact of an antibiotic stewardship intervention on provider prescribing behavior for acute respiratory infections (ARIs), where the intervention is administered…
- Conditions
- Antimicrobial Stewardship, Acute Bronchitis, Upper Respiratory Infection
- Trial name
- NCT03711292
- Testing
- Antibiotic Stewardship
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Drug Resistance, Microbial, Antimicrobial Stewardship
Gonorrhoea Resistance Assessment by Nucleic Acid Detection (GRANDII)
Three sexual health clinical services across Australia and their associated pathology testing laboratories are implementing a new management program for gonorrhoea infection.
- Conditions
- Drug Resistance, Microbial, Antimicrobial Stewardship, Gonorrhea
- Trial name
- GRANDII (NCT04268342)
- Testing
- Resistance guided treatment for gonorrhoea infection
- Where
- Australia
- Volunteers
- 1,626 people
- Sponsor
- The University of Queensland
Antimicrobial Stewardship, Exacerbation of Allergic Asthma
POCT PCT in Outpatient LRTI
Lower respiratory tract infections (LRTI) in patients with chronic lung diseases are a common acute reason to consult respiratory practitioners and often lead to inadequate prescription of antibiotics.
- Conditions
- Antimicrobial Stewardship, Exacerbation of Allergic Asthma, Exacerbation Copd, Community-acquired Pneumonia
- Trial name
- POCT-PCT (NCT05380869)
- Testing
- Point-of-care Test
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- Hannover Medical School
Antimicrobial Stewardship
The Impact of the Establishment of a New AMS CPS in a Rural Hospital in Austria
Antimicrobial stewardship groups ensure the safe and prudent use of antibiotics, decrease antimicrobial resistance, lower costs of antimicrobials in hospital settings and improve patient safety in terms of prescribing…
- Trial name
- NCT05370846
- Testing
- Clinical pharmacy antimicrobial stewardship intervention
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Antimicrobial Stewardship, Cardiovascular Surgeries
Evaluation of the Potential Impact of Computerized Antimicrobial Stewardship
This trial is an open-label, two-arm, cluster-randomized, controlled trial with cardiovascular surgical teams as the unit of randomization.
- Conditions
- Antimicrobial Stewardship, Cardiovascular Surgeries, Computerized Decision Support System, Coronary Artery Disease
- Trial name
- EPIC (NCT04328090)
- Testing
- Computer based Antimicrobial stewardship (AMS) intervention system
- Where
- China
- Volunteers
- 2,473 people
- Sponsor
- China National Center for Cardiovascular Diseases
Antimicrobial Stewardship, Urinary Tract Infections
Nurse-led Antimicrobial Stewardship Intervention to Increase Antibiotic Appropriateness in Residential Aged Care Facilities
The study will explore the impact of a nurse-led bundled antimicrobial stewardship intervention on the appropriateness of antimicrobial use in residential aged care facilities.
- Conditions
- Antimicrobial Stewardship, Urinary Tract Infections, Respiratory Tract Infections, Skin and Soft Tissue Infections
- Trial name
- NCT03941509
- Testing
- Antimicrobial stewardship
- Where
- Australia
- Volunteers
- 700 people
- Sponsor
- Bayside Health