Clinical trials: Anterior Cruciate Ligament (ACL)
Anterior Cruciate Ligament Rupture
Effects of Corporal Visualisation Program of the Static and Dynamic Balance After an Operation of the LCA
The aim of this pilot study is to assess the feasibility of a RCT whose topic would be the effect of a motor imagery program on the postural control in persons who have undergone ACL plasty.
- Trial name
- NCT05081661
- Testing
- Motor Imagery Program
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- HES-SO Valais-Wallis
ACL, Anterior Cruciate Ligament Injury
Decreasing Knee Injury Risk Factors With Neuromuscular Training
Anterior cruciate ligament (ACL) tears are disabling injuries that place a significant burden on the athlete. Roughly 80% of these injuries are linked to a noncontact mechanism, with more than 70% of them occurring while landing…
- Trial name
- NCT01433718
- Testing
- Neuromuscular and Resistance Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio University
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Anterior Cruciate Ligaments: Studying Updates in neuroCognition After Knee Manipulation
This study will investigate whether knee joint manipulation can improve neurocognitive and neuromuscular performance in individuals with a history of anterior cruciate ligament reconstruction (ACLR).
- Trial name
- ACLs SUCK (NCT07058467)
- Testing
- Joint Manipulation
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Anterior Cruciate Ligament Tear
IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Injury to the knee during sports participation often involves partial or full detachment of the anterior cruciate ligament (abbreviated as ACL). ACL tears cause pain, swelling and inflammation.
- Trial name
- EASI ACL (NCT02930122)
- Testing
- anakinra (150mg), Saline intraarticularly
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cale Jacobs, PhD
Articular Cartilage Degeneration
MechSens - Dose-response Relationship of in Vivo Ambulatory Load and Mechanosensitive Cartilage Biomarkers
This study is to investigate the effects of age, tissue status and the presence of inflammation on the in vivo dose-response relationship of ambulatory load and mechanosensitive blood markers of articular cartilage.
- Trial name
- MechSens (NCT04128566)
- Testing
- walking stress test
- Where
- Switzerland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
ACL Reconstruction, Cognitive Function
Test of Return to Sport After ACL Reconstruction and Cognitive Task.
After reconstruction of the anterior cruciate ligament, the aim for the vast majority of sportspeople is to return to the field.
- Conditions
- ACL Reconstruction, Cognitive Function, Single Leg Hop Firm Surface, Testing Effect of Intervention
- Trial name
- AQQSHTATC (NCT06768957)
- Testing
- Single leg hop for distance, Single leg hop for distance plus cognitive task
- Where
- 4 sites in France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Simon VALOT
ACL Tear, ACL-injury
Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?
The goal of this prospective, cross-sectional study is to test the strength of the soleus muscle in participants who have a ACL tear confirmed by MRI.
- Conditions
- ACL Tear, ACL-injury, ACL - Anterior Cruciate Ligament Rupture
- Trial name
- ACL (NCT06235736)
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Anterior Cruciate Ligament Reconstruction Rehabilitation, Blood Flow Restriction (BFR) Training Effects
Effect of Blood Flow Restriction Rraining on Rehabilitation After Anterior Cruciate Ligament Reconstruction
Importance: Following anterior cruciate ligament reconstruction (ACLR), patients often experience quadriceps muscle weakness and atrophy, frequently leading to long-term complications.
- Trial name
- NCT07311031
- Testing
- Blood flow restriction training, Standard ACL rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital MAZ
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Anterior Cruciate Ligament Injuries
A Study Of Focused Shockwave For Anterior Knee Pain Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to investigate whether Focused Shockwave (FSW) therapy reduces anterior knee pain following anterior cruciate ligament reconstruction (ACL-R) with bone-patellar tendon-bone (BTB) or quadriceps tendon…
- Trial name
- NCT07580157
- Testing
- Focused Shockwave
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Rupture
"Online Surveys" in Perioperative Knee Anterior Cruciate Ligament (ACL) Reconstruction
To monitor the quality of health care systems, patient-reported outcome measures (PROMs) should be collected and analyzed before and after medical interventions.
- Trial name
- ORTHENSE (NCT05423314)
- Testing
- knee brace cold therapy
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Anterior Cruciate Ligament Injuries, Knee Injuries
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes.
- Trial name
- LCA-WOMEN (NCT07722104)
- Testing
- Hamstring tendon autograft ACL reconstruction, Quadriceps tendon autograft ACL reconstruction
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR
In Hong Kong, over 3000 Anterior Cruciate Ligament Reconstructions (ACLR) are performed each year in order to restore knee function after an ACL injury. The ultimate goal of ACLR is to fulfil the return-to-play (RTP) criteria.
- Trial name
- NCT05184023
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament (ACL) Tear
Conventional Follow-up Versus Mobile App For Post-Operative ACL Reconstruction Patients
Background: Telemedicine is increasingly used to overcome distance between patients and physicians. Preliminary studies suggest that mobile app follow-up care for ACL reconstruction patients is feasible, can avert in-person…
- Trial name
- NCT02942940
- Testing
- mobile app, conventional in-person
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Toronto Orthopaedic Sports Medicine
ACL Reconstruction
Efficacy and Tolerability of a Nutritional Supplement, Plactive Progen, in ACL Reconstruction
This was a prospective, multicenter, randomized, open-label, phase IV trial to compare the efficacy of supplementation with plasma proteins, hydrolyzed collagen (CH), a complex of HA-CS (HC-15), and vitamin C combined with a…
- Trial name
- NCT03355651
- Testing
- PROGEN
- Volunteers
- 80 people
- Sponsor
- OPKO Health, Inc.
Osteoarthritis, Arthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): 10 Year Onsite Follow-up
In this study the investigators will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction…
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02717559
- Volunteers
- 225 people
- Sponsor
- Vanderbilt University Medical Center
Injury of Anterior Cruciate Ligament
Sport Cord Test Following ACL Reconstruction
The primary purpose of this study is to determine the interrater reliability and validity of the Sportcord Test as a measure of physical performance following anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT01937403
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- The Hawkins Foundation
Anterior Cruciate Ligament Tear
Primary Anterior Cruciate Ligament Repair With and Without Lateral Extraarticular Tenodesis
The investigators aimed to compare the clinical results of primary repairs and Lateral Extraarticular Tenodesis applied with primary repairs in the treatment of proximal ACL tears.
- Trial name
- NCT05923710
- Testing
- Primary anterior cruciate ligament repair, Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Anterior-cruciate Ligament Knee Injury
Utilization of Rehabilitation Prior to Surgery Among Patients With Anterior-cruciate Ligament Knee Injury
This research aims to assess physiotherapy utilization in the treatment of patients with an anterior-cruciate ligament knee injury, when delivered before their surgery (prehab), and its potential effects on absence from work, and…
- Trial name
- prehab-ACL (NCT05737719)
- Testing
- Rehabilitation before knee surgery (prehab), Post-surgery rehabilitation
- Where
- France
- Volunteers
- 864,000 people
- Sponsor
- Nantes University Hospital
Anterior Cruciate Ligament Injuries
Adding Neurocognitive Component to Balance Test
By introducing BlazePods as a neurocognitive addition to the YBT, this study aims to determine whether this addition impacts balance performance and/or reach distances between the operative and non-operative limbs of patients…
- Trial name
- NCT06827483
- Testing
- Neurocognitive Component
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University