Clinical trials: Anterior Cervical Discectomy, active
Cervical Stenosis, Spondylolisthesis
Effectiveness of AlloWrap® for the Reduction of Inflammation in ACDF Procedures
The primary objective of this study is to obtain evidence of the effectiveness of AlloWrap Amniotic Membrane in the reduction of soft tissue swelling in two-level ACDF procedures.
- Conditions
- Cervical Stenosis, Spondylolisthesis, Cervical Radiculopathy, Cervical Disc Disorder
- Trial name
- NCT04684901
- Testing
- AlloWrap® Amniotic Membrane
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AlloSource
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Cervical Disc Prolapse
Functional Outcome After Combined Posterior Laminectomy and Anterior Cervical Discectomy and Fusion for Large Cervical Disc Prolapse
Cervical disc herniation (CDH) is the result of the displacement of the nucleus pulposus of the intervertebral disc, which may result in impingement of the traversing nerves as they exit the neural foramen or directly compressing…
- Trial name
- NCT06847503
- Volunteers
- 25 people
- Sponsor
- Assiut University
Cervical Degenerative Disease
ACDf: Stand Alone Cage Versus Cage Screw Fixation
Cervical degenerative disc disease is a common spinal disorder causing significant morbidity worldwide, Patients commonly present with neck pain, cervical radiculopathy, myelopathy, sensory disturbances, motor weakness, and gait…
- Trial name
- NCT07713927
- Testing
- Anterior Cervical Discectomy and fixation, Anterior Cervical Discectomy and fixation using stand alone cage
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Cervical Spine Degeneration, ACDF Surgery
Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapy
The goal of this two-group randomized clinical trial is to examine the effects of early postoperative PT compared to delayed postoperative PT for improving outcomes after hospital discharge for ACDF surgery.
- Trial name
- FAST-PT (NCT06202443)
- Testing
- Early PT, Delayed PT
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Vanderbilt University Medical Center
Degenerative Disc Disease
ACDF Using Structural Allograft vs. Tritanium C
This is an observational, descriptive, prospective and retrospective data collection study. The purpose of this study is to observe radiographic outcomes of patients who will undergo anterior cervical discectomy and fusion (ACDF)…
- Trial name
- NCT04388332
- Testing
- Structural allograft, Tritanium C
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Cervical Radiculopathy, Cervical Myelopathy
Prospective Comparative Analysis of ACDF vs Fusion Interbody Cages With nanoLOCK Osseointegrative Technology
Study team will plan a prospective, randomized control trial using our institution's spine clinical outcomes registry. Eligible patients undergoing ACDF (see inclusion criteria listed below) will be randomized to an Intervention…
- Trial name
- NCT05762055
- Testing
- Titan nanoLOCK interbody cage, ACDF interbody cage
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Cervical Degenerative Disc Disease
The Synergy Disc To Anterior Cervical Discectomy and Fusion
A multicenter, prospective, non-randomized, historically controlled study. Demonstrate the Synergy Disc is at least as safe and effective as conventional anterior cervical discectomy and fusion (ACDF) to treat cervical…
- Trial name
- NCT04469231
- Testing
- Anterior Cervical Discectomy & Fusion
- Where
- 20 sites in United States
- Volunteers
- 175 people
- Sponsor
- Synergy Spine Solutions
Cervical Disc Disease, Cervical Radiculopathy
Rehabilitation After Anterior Cervical Discectomy and Fusion
Anterior cervical discectomy and fusion (ACDF) is a commonly performed surgical procedure for cervical disc herniation, cervical radiculopathy, and degenerative cervical spine disorders.
- Conditions
- Cervical Disc Disease, Cervical Radiculopathy, Postoperative Dysphagia
- Trial name
- ACDF-REHAB (NCT07814950)
- Testing
- Structured Postoperative Rehabilitation Program, Standard Postoperative Follow-up
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Cervical Disc Degeneration
Study to Evaluate the Clinical and Radiographic Outcomes of the BEE® HA Cage for Anterior Cervical Discectomy and Fusion
Observational data collection of information after undergoing standard Cervical spine fusion surgery.
- Trial name
- NCT05631392
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Invibio Ltd
Cervical Disc Herniation, Cervical Foraminal Stenosis
Endoscopic Posterior Cervical Foraminotomy Versus Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy
Cervical radiculopathy caused by cervical disc herniation or foraminal stenosis is a common condition that may result in upper limb pain, sensory disturbances, and motor deficits.
- Conditions
- Cervical Disc Herniation, Cervical Foraminal Stenosis, Cervical Radiculopathy
- Trial name
- ENDOFOR (NCT07894159)
- Testing
- Uniportal Endoscopic Posterior Cervical Foraminotomy, Anterior Cervical Discectomy and Fusion
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Central Hospital, Nancy, France
Dysphagia
Anterior Cervical Discectomy and Fusion (ACDF) - Behavioral Intervention
This study will prospectively recruit and enroll patients undergoing primary Anterior Cervical Discectomy and Fusion (ACDF) surgeries at NYU Langone.
- Trial name
- NCT06520579
- Testing
- Proactive pharyngeal-laryngeal Exercise Program, Premier Protein Clear ® High Protein, Hydration Counseling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Anterior Cervical Discectomy, Peripheral Nerve Block
Comparison of the Postoperative Analgesic Efficacy of SPSIPB and ESPB in Anterior Cervical Discectomy
Anterior cervical discectomy is an operation performed for complaints of pain, numbness or loss of strength due to cervical disc disease.
- Conditions
- Anterior Cervical Discectomy, Peripheral Nerve Block, Pain Management
- Trial name
- NCT06639022
- Testing
- Serratus posterior superior intercostal plane block, Erector spinae plane block, Group without peripheral nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ankara Etlik City Hospital
Degenerative Disc Disease(DDD)
Evaluation of the Safety and Effectiveness of the CORUS™ Posterior Cervical Stabilization System 3D (PCSS 3D) for the Treatment of 2-level Cervical Degenerative Disease
The objective of this clinical trial is to evaluate the treatment of patients with two-level cervical degenerative disease using a combination of Anterior Cervical Discectomy and Fusion (ACDF) and Posterior Cervical Fusion (PCF)…
- Trial name
- SECOND (NCT07721493)
- Testing
- Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Providence Medical Technology, Inc.
Neck Pain, Cervical Spondylosis
Predictors of Axial Pain Improvement After Anterior Cervical Discectomy and Fusion
Neck pain is a common, multifactorial condition. In the case of degenerative cervical spinal disease, it can result from changes in the intervertebral discs, muscles, intervertebral joints, or sagittal imbalance.
- Conditions
- Neck Pain, Cervical Spondylosis, Cervical Disc Disease
- Trial name
- NCT06601634
- Where
- 2 sites in Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Symptomatic Cervical Disc Disease
Exploratory Study of 3D Printed Biodegradable Cervical Interbody Fusion Cage
A small sample, single center, non-randomized, noninferiority clinical trial to evaluate the safety and effectiveness of 3D printed biodegradable cervical interbody fusion cage in anterior cervical discectomy and fusion (ACDF)…
- Trial name
- NCT04167878
- Testing
- 3D printed biodegradable cervical fusion cage, PEEK cage
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cervical Cage With Screw, Cervical Degenerative Disc Disease
Screw-Integrated vs Traditional Cervical Cages in ACDF for Degenerative Disc Disease
This study is a prospective, comparative clinical trial conducted at Assiut University Hospitals to evaluate the effectiveness of two different interbody fusion devices in patients with Cervical Degenerative Disc Disease (CDDD).
- Conditions
- Cervical Cage With Screw, Cervical Degenerative Disc Disease, Anterior Cervical Discectomy and Fusion (ACDF)
- Trial name
- NCT07430163
- Testing
- cervical cage with integrated screws, traditional standalone cervical cage
- Volunteers
- 40 people
- Sponsor
- Assiut University
ACDF Surgery
Post-operative Outcomes of Anterior Cervical Discectomy and Fusion Surgery With and Without Drain Placement
Anterior Cervical Discectomy and Fusion (ACDF) is a widely performed surgical procedure used to treat cervical spondylosis and cervical disc herniations with cervical nerve root compression and or cervical spinal cord compression…
- Trial name
- NCT06938607
- Testing
- Drain
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Nebraska
Cervical Degenerative Disc Disease
The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery
A multicenter, prospective, non-randomized, historically controlled study. To demonstrate the Synergy Disc is at least as safe and effective as conventional anterior cervical discectomy and fusion (ACDF) to treat cervical…
- Trial name
- NCT05740176
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- 23 sites in United States
- Volunteers
- 200 people
- Sponsor
- Synergy Spine Solutions