Clinical trials: Anorectal Malformations
Bowel Dysfunction, Dysmotility
Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children
The goal of this clinical trial is to learn if the new non-invasive device (Body Surface Colonic Mapping) works to accurately assess colonic movement and function in children.The main questions it aims to answer are: Are Body…
- Conditions
- Bowel Dysfunction, Dysmotility, Hirschsprung Disease, Anorectal Malformations
- Trial name
- NCT07789782
- Testing
- Body Surface Colonic Mapping
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
Anorectal Malformations
Study of Antenatal and Postnatal Data of Anorectal Malformations Diagnosed at Montpellier University Hospital Over a 10-year Period (2010-2020)
Objective : Anorectal malformations (ARMs) are part of a spectrum of malformations due to an abnormal separation between the urogenital and digestive tracts during embryonic life.
- Trial name
- NCT05045560
- Where
- France
- Volunteers
- 98 people
- Sponsor
- University Hospital, Montpellier
Anorectal Malformations
Longterm Outcomes of Individuals With Anorectal Malformations
This is a cross-sectional observational study with the aim to assess longterm outcomes in a large cohort of individuals with anorectal malformations.
- Trial name
- NCT04901819
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Karolinska Institutet
Anal Stenosis
V-Y Flap for Anal Stenosis
anal stenosis is a common complication after massive open hemorrhoidectomy. it interferes with the patient daily activities. Many interventions were described, but there is no standard treatment.
- Trial name
- NCT06860906
- Testing
- V-Y advancement flap
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Zagazig University
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Non-invasive Sacral Nerve Stimulation in Children and Adolescents With Chronic Constipation
The purpose of this study is to assess the efficacy of additional neuromodulation for treatment of chronic constipation in pediatric patients
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschprung's Disease, Anorectal Malformations
- Trial name
- NCT04710433
- Testing
- Non-invasive Neuromodulation, Medical and Behavioral Therapy
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Anorectal Malformations
Frequency of Vertebrospinal Anomalies in Patients Presenting With Anorectal Malformations
To determine the frequency of different vertebrospinal anomalies in patients with ARM
- Trial name
- NCT06234020
- Testing
- To see the frequency of vertebrospinal anomalies in patients presenting with Anorectal Malformation
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Vestibular Fistulae
Rectovestibular Fistula Which Surgical Approaches?
This study was a prospective, randomized, comparative study that included female children with rectovestibular fistulae who were selected from patients with anorectal malformations treated at the pediatric surgical unit, Assiut…
- Trial name
- Vestibanus (NCT04970160)
- Testing
- TSARP, PSARP, Classic ASARP
- Volunteers
- 84 people
- Sponsor
- Aswan University Hospital
Hirschsprung Disease, Anorectal Malformations
Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations
Approximately 340 babies are born with Hirschsprung's disease (HSCR) or an anorectal malformation (ARM) per year in the UK. Most require corrective surgery in the newborn or early infancy period.
- Trial name
- ALOHA (NCT05450991)
- Testing
- Pull through
- Where
- United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Anorectal Malformations
Baylor Continence Scale Validity in Anorectal Malformation
The aim of this study is to evaluate the validity and reliability of the Baylor Continence Scale in Turkish-speaking children diagnosed with anorectal malformations.
- Trial name
- NCT07029984
- Testing
- Baylor Continence Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Izmir Bakircay University
Anorectal Malformations
Outcomes in ARMs: Comparison Between Surgical Techniques in Patients With Perineal or Vestibular Fistula - a Multicenter Italian Study
This is a national, multicenter, retro-prospective longitudinal cohort study evaluating mid- and long-term outcomes of different surgical techniques used for the correction of anorectal malformations (ARM) with perineal or…
- Trial name
- MAR-ITA (NCT07438691)
- Where
- 21 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Anorectal Malformation
Laparoscopically Assisted Anorectal Pull-through Versus Posterior Sagittal Anorectoplasty
Anorectal malformations are congenital malformations, in which the terminal part of the hindgut is abnormally placed and lies outside (partially or completely) the sphincter mechanism.
- Trial name
- NCT03174028
- Testing
- laparoscopic pull-through
- Volunteers
- 30 people
- Sponsor
- Assiut University
Anorectal Malformations, Transition
Transition of Care for Patients With Hirschsprung Disease and Anorectal Malformations
Transition from paediatric to adult health care is crucial for preventing deterioration of chronic diseases. At present, transitional care (TC) is not established for patients with the Hirschsprung disease (H) and Anorectal…
- Conditions
- Anorectal Malformations, Transition, Quality of Life, Hirschsprung Disease
- Trial name
- NOHARM (NCT04106947)
- Testing
- Questionnaires
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Oslo University Hospital
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Anorectal Malformations
Parental Attitudes to Neoanus Dilatations Post-reconstruction in Anorectal Malformations
The goal of this qualitative clinical trial is to learn about parental attitudes and experiences of performing post-operative dilatation anal dilatations for their child with an anorectal malformation.
- Trial name
- PANDA (NCT05749406)
- Testing
- Focus group, Semi-structured interview
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Verity Haffenden
Bowel Cleansing Prior to Clinical Procedures, Colorectal Anastomosis
Oral Antibiotics vs. No Antibiotics in Pediatric Colorectal Surgery
This study aims to evaluate whether giving oral antibiotics before elective colorectal surgery can improve recovery and reduce complications in children.
- Trial name
- PEACO (NCT07713433)
- Testing
- oral antibiotics, No Oral Antibiotics
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Muhammad Zubair Shoukat
Hirschsprung Disease, Anorectal Malformations
Feasibility of Use of Indocyanine Green in Pediatric Colorectal Surgery
Hirschsprung's Disease (HD) and anorectal malformations (ARM) are both paediatric diseases of the colon and rectum. Both of these conditions require surgery in order to correct them, frequently needing sections of the bowel to be…
- Trial name
- NCT04904081
- Testing
- Indocyanine green
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anorectal Malformation
Urodynamic Evaluation in Patients With Anorectal Malformation According to Spinal Cord Abnormalities
This study will examine the effects of spinal cord abnormalities on perioperative neurovesical dysfunction in patients with anorectal abnormalities.
- Trial name
- NCT00909415
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Yonsei University
Inflammatory Bowel Diseases, Anorectal Malformations
StoMakker Mobile Application
The goal of this clinical trial is to investigate if access to the StoMakker application will significantly improve health-related quality of life in children receiving surgery resulting in an ileostomy, colostomy or continent…
- Conditions
- Inflammatory Bowel Diseases, Anorectal Malformations, Spina Bifida, Ostomy
- Trial name
- StoMakker (NCT06065995)
- Testing
- StoMakker
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anorectal Malformation, Hirschprung's Disease
Long-Term Health Outcomes in Children Born With Hirschsprung's Disease and Anorectal Malformations at the Colorectal Centre of Excellence in Quebec
The COCOE Registry is a long-term research registry based at the Montreal Children's Hospital Colorectal Centre of Excellence (COCOE) in Montreal, Quebec.
- Conditions
- Anorectal Malformation, Hirschprung's Disease, Colo-rectal Surgery, Fecal Incontinence
- Trial name
- NCT07603232
- Testing
- No intervention (observational study)
- Where
- Canada
- Volunteers
- 999 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Children, Anorectal Disorder
3D High Resolution Anorectal Manometry in Children After Surgery for Anorectal Disorders
3D high resolution anorectal manometry (3DHRAM) is the most precise tool to assess function and 3D topographic picture of pressures along the anal canal.
- Conditions
- Children, Anorectal Disorder, Anorectal Atresia, Hirschsprung Disease
- Trial name
- NCT02296008
- Testing
- 3D high resolution anorectal manometry
- Where
- Poland
- Volunteers
- 43 people
- Sponsor
- Medical University of Warsaw