Clinical trials: Ankle Arthritis, active
Ankle Arthritis, Wound Complication
The Use of Tranexamic Acid in Decreasing Wound Complication in Total Ankle Replacement.
Patients who undergo total ankle replacement surgery can sometimes develop problems with wound healing after their operation. These complications may include delayed healing, wound opening, or infection, which can lead to…
- Trial name
- TXA in TAR (NCT07828262)
- Testing
- Transexamic acid, Normal Saline (0.9% NaCl)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Ankle Rheumatoid Arthritis, Arthritis of Ankle
Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only
The objectives of this study are to evaluate the performance and safety of the Vantage Total Ankle System. This study will follow subjects for a period of up to 10 years post-surgery.
- Conditions
- Ankle Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
- Trial name
- NCT05619588
- Where
- 2 sites in United States
- Volunteers
- 370 people
- Sponsor
- Exactech
Rheumatoid Arthritis, Arthritis of Ankle
Vantage Mobile Bearing Total Ankle System Post Market Clinical Follow-up (Outside US)
The objectives of this study are to evaluate the performance and safety of the Vantage Mobile-Bearing Total Angle System. This study will follow subjects for a period of up to 10 years post-surgery.
- Conditions
- Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
- Trial name
- NCT05691868
- Where
- 2 sites in Spain, Switzerland
- Volunteers
- 400 people
- Sponsor
- Exactech
Arthritis Ankle, Arthritis Knee
Investigation of Growth Hormone and Platelet-Rich Plasma on Joint Health
This clinical study will evaluate the efficacy and safety of intra-articular (IA) recombinant human growth hormone (rhGH; somatropin) combined with platelet-rich plasma (PRP) in adults with treatment-resistant knee and ankle…
- Trial name
- NCT06907121
- Testing
- Intra-Articular Injection of Growth Hormone and Platelet-Rich Plasma
- Where
- Australia
- Volunteers
- 192 people
- Sponsor
- Integrant Pty Ltd
Post Traumatic Arthritis, Osteoarthritis
A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
The goal of this study is to demonstrate the safety and performance of the Incompass™ Total Ankle System after surgery over the standard follow-up period.
- Conditions
- Post Traumatic Arthritis, Osteoarthritis, Total Ankle Replacement, Total Ankle Prosthesis
- Trial name
- NCT07118501
- Testing
- Total Ankle Replacement
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stryker Trauma and Extremities
Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle
Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System
The H3 TAR Prosthesis was approved by FDA (P160036) on June 4, 2019. Continued approval of the premarket approval application (PMA) is contingent upon the submission of periodic reports (Annual Report), required under 21 CFR…
- Conditions
- Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle, Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
- Trial name
- NCT04770870
- Testing
- Hintermann Series H3 Total Ankle Replacement System
- Where
- 11 sites in United States
- Volunteers
- 94 people
- Sponsor
- DT MedTech, LLC
Arthrosis, Ankle Arthritis
Outcomes of Surgical Treatment Using a Custom-made Device for Total Ankle and Talar Replacement in the Management of Severe Cases of Bone Loss or Bone Compromise: a Pilot Study.
On February 17th, 2021, the FDA officially approved the use of the first patient-specific 3D-printed talar implant for compassionate use.
- Conditions
- Arthrosis, Ankle Arthritis, Ankle Replacement
- Trial name
- NCT07569848
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Istituto Ortopedico Rizzoli
Arthritis, Femoroacetabular Impingement
Conjoint Analysis of Patient Preferences in Joint Interventions
This study is an observational study to test and validate a questionnaire and statistical model used to determine patient preferences regarding treatment for any one of 11 musculoskeletal conditions: hip arthritis, knee…
- Conditions
- Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures
- Trial name
- NCT02664337
- Testing
- Decision tool, Standard treatment information
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Duke University
Ankle Arthritis
Incidence of Subtalar Joint Fusion After Isolated Ankle Fusion
It is important to know a truer incidence of the need for subtalar and midfoot fusions, following an isolated ankle fusion, in order to better inform our patients of the likelihood of needing further surgery in the future.
- Trial name
- NCT06782269
- Testing
- ankle fusion
- Volunteers
- 400 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Infections, Ankle Arthritis
Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty
The purpose of this study is to compare two different antibiotic regimens and techniques during total ankle arthroplasty (TAA). Primary Objective: Comparable levels of vancomycin will be found in bone, soft tissue, and systemic…
- Trial name
- IOTAA (NCT06384651)
- Testing
- Intraosseous Vancomycin Injection, Intravenous Vancomycin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Methodist Hospital Research Institute
Osteoarthritis, Osteo Arthritis Knee
Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis
Use of Biocellular and cellular approaches to treatment of Osteoarthritis (OA), musculoskeletal aging processes, pain, and degenerative changes are to be studied with minimally invasive protocols, and non-pharmaceutical means to…
- Conditions
- Osteoarthritis, Osteo Arthritis Knee, Osteo Arthritis Shoulders, Osteoarthritis of Multiple Joints
- Trial name
- GARM-MSK-ALD (NCT04238143)
- Testing
- Tissue Stromal Vascular Fraction (tSVF) Arm 1, PRP Concentrate Arm 1, Tissue Stromal Vascular Fraction (tSVF) Arm 2
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Healeon Medical Inc
Ankle Arthritis
Canadian Orthopaedic Foot and Ankle Society Surgical Treatment of Ankle Arthritis Outcome Study
The purpose of this study is to see if the clinical outcome success rate of Total Ankle Arthroplasty is similar to that of Ankle Arthrodesis over a period of 10 years.
- Trial name
- NCT00552136
- Testing
- Ankle Arthroplasty, Ankle Arthrodesis
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Nova Scotia Health Authority
Ankle Arthritis
Total Ankle Replacement: Clinical and Radiological Outcomes
This retrospective and prospective study intends to evaluate the epidemiology and effectiveness of ankle joint surgery in patients operated from January 2011 to March 2026, evaluating the results both clinically and…
- Trial name
- NCT03650010
- Testing
- Total ankle replacement
- Where
- Italy
- Volunteers
- 1,066 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio