Clinical trials: Anismus
Constipation
Mechano-physiological Approach to Anorectal Function
We hypothesize that defecatory disorders can be described in mechanical terms which would allow a mechanistic description of disorders which would in turn allow better directed biofeedback mechanisms to treat disorders of…
- Trial name
- NCT00219518
- Testing
- defecography
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dyssynergic Defaecation, Evacuation Disorder
Infracoccygeal Botox for Dyssynergia
Background: Constipation is a common problem, affecting up to 20% of the population during their lifetime. Some patients respond poorly to standard treatments such as laxatives.
- Conditions
- Dyssynergic Defaecation, Evacuation Disorder, Anismus, Defecation Disorder
- Trial name
- NCT04879524
- Testing
- Percutaneous infracoccygeal Botulinum toxin injection to puborectalis
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Queen Mary University of London
Anismus, Incontinence
Seated Evaluation of Anorectal funcTion by High Resolution Anorectal Manometry
To assess whether HR-ARM (High resolution Anorectal Manometry) performed in the more naturalistic / physiological upright, seated position on a commode provides a more valid assessment of anorectal function and simulated…
- Trial name
- SEAT (NCT02633592)
- Testing
- HRARM, MRI Defecography
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gastric Outlet Obstruction, Rectocele
RCT: STARR vs Biofeedback
This study aimed to evaluate the safety and symptomatic outcomes achieved with Stapled Transanal Rectal Resection (STARR) compared to biofeedback training in patients with obstructed defecation syndrome (ODS).
- Conditions
- Gastric Outlet Obstruction, Rectocele, Intussusception, Anismus
- Trial name
- ODS II (NCT00556283)
- Testing
- STARR, Biofeedback
- Where
- 9 sites in France, Italy and 1 more
- Volunteers
- 121 people
- Sponsor
- Ethicon Endo-Surgery (Europe) GmbH
Constipation, Chronic Constipation
Balloon Inflation in Biofeedback
Chronic constipation, particularly due to dyssynergic defecation, is common and impacts quality of life. Biofeedback therapy (BFT) is the most effective conservative treatment, teaching patients to coordinate abdominal and anal…
- Conditions
- Constipation, Chronic Constipation, Dyssynergia, Anismus
- Trial name
- NCT07705542
- Testing
- Inflating anorectal catheter balloon to defecatory desired volume during push manoeuvres in biofeedback therapy., No intervention
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Anismus, Distal Constipation
Is the Evaluation of Anal Distensibility by Endoflip® Technique Useful for the Diagnosis of Anismus?
Terminal constipation affects 13 to 20% of the french population. Anismus is defined by an absence of relaxation or a paradoxical contraction of the striated anal sphincter muscle during defecation.
- Trial name
- Endo-DC (NCT04155307)
- Testing
- Anal EndoFLIP®, Anal Manometry, Defecography
- Where
- France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Rouen
Pelvic Pain, Levator Ani Syndrome
Photobiomodulation for Myofascial Pelvic Pain
The goal of this clinical trial is to evaluate the efficacy of photobiomodulation of the pelvic floor muscles in female Veterans with chronic pelvic pain.
- Conditions
- Pelvic Pain, Levator Ani Syndrome, Spastic Pelvic Floor Syndrome, Chronic Pelvic Pain Syndrome
- Trial name
- PMPP (NCT05926752)
- Testing
- SoLá therapy, Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Orlando VA Medical Center
Pain After Stapled Haemorrhoidopexy
Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy
This study wants demonstrate that the use of 0.4% nitroglycerin ointment can reduce the postoperative pain related to anorectal spasm (anismus) while performing a stapled haemorrhoidopexy.
- Trial name
- TAGASH (NCT01279551)
- Testing
- 0.4% nitroglycerin ointment, lidocaine cloridrato 2.5% ointment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Obstructed Defecation, Anismus
Comparative Study Between Surgical and Non Surgical Treatment of Anismus in Patients
Comparative study between surgical and non surgical treatment of anismus in patients with symptoms of obstructed defecation. Anismus is a significant cause of chronic constipation.
- Conditions
- Obstructed Defecation, Anismus, Constipation
- Trial name
- NCT00735605
- Testing
- BFD, PDPR, BTX A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University