Clinical trials: Angle-Closure Glaucoma
Glaucoma, Open-Angle, Glaucoma, Angle-Closure
Keratometric Change After XEN, Trabeculectomy and Tube Shunts
The main goal of this study is to assess the severity of postoperative corneal astigmatism induced by implantation of the XEN Gel Stent compared to that induced by traditional filtering surgery (trabeculectomy and GDDs).
- Conditions
- Glaucoma, Open-Angle, Glaucoma, Angle-Closure, Glaucoma Secondary, Glaucoma Eye
- Trial name
- Topo-XEN (NCT04602923)
- Testing
- Corneal topography: OPD-Scan, Corneal topography: Pentacam
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acute Angle-Closure Glaucoma
Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma
To investigate the changes of angle structure and intraocular pressure after argon laser peripheral iridoplasty in patients with acute angle closure glaucoma patients whose intraocular pressure could not be controlled by drug…
- Trial name
- NCT04912310
- Testing
- Argon laser peripheral iridoplasty
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Angle Closure Glaucoma
Comparing Nd:YAG Laser and Sequential Double Frequency YAG-Nd:YAG Laser Iridotomy
No single type of laser or set of laser parameters is appropriate for all type of irides. Pure Nd:YAG laser iridotomy is very effective in the light color irides. It was considered as the gold standard for iridotomy.
- Trial name
- NCT02474238
- Testing
- The sequential technique, The pure Nd:YAG laser technique
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Prince of Songkla University
Chronic Angle Closure Glaucoma
Prevalence of Angle Closure in Caucasian Hyperopes
The primary purpose of this study is to assess the prevalence of asymptomatic chronic angle closure in high risk Caucasian individuals, namely those with hyperopia.
- Trial name
- NCT00823706
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Glaucoma, Closed-Angle
Cataract Surgery Combined With Endoscopic Goniosynechialysis for Advanced Primary Angle Closure Glaucoma
In this prospective study, consecutive patients with advanced PACG and cataract who underwent Phaco-IOL-EGSL were invited to participate.
- Trial name
- NCT03686072
- Testing
- Cataract surgery with endoscopic goniosynechialysis
- Volunteers
- 19 people
- Sponsor
- Wenzhou Medical University
Open Angle Glaucoma, Angle Closure Glaucoma
Oculusgen (Ologen) Glaucoma MMC Control in Estonia
To compare the safety and effectiveness between ologen collagen matrix and mitomycin-C (MMC) in glaucoma surgery. The ologen collagen matrix implantation procedure is same as traditional trabeculectomy except implant the ologen…
- Conditions
- Open Angle Glaucoma, Angle Closure Glaucoma, Uveitis Glaucoma, Young Age Glaucoma
- Trial name
- NCT00524758
- Testing
- ologen (oculusgen) collagen matrix, MMC in Trabeculectomy
- Where
- Estonia
- Volunteers
- 20 people
- Sponsor
- Pro Top & Mediking Company Limited
Glaucoma, Angle-Closure
Phaco-ECP vs Phaco Alone in Primary Angle Closure
Comparison between phacoemulsification with endoscopic cyclophotocoagulation versus phacoemulsification alone in patients with either primary angle closure or primary angle closure glaucoma presenting with cataract or a clear…
- Trial name
- PHEPHA (NCT04562402)
- Testing
- Phacoemulsification, Endoscopic cyclophotocoagulation
- Where
- Saudi Arabia
- Volunteers
- 104 people
- Sponsor
- King Khaled Eye Specialist Hospital
Glaucoma, Angle-Closure
AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification
Evaluation of the effect of phacoemulsification and YAG Laser peripheral iridotomy on the anterior chamber angle anatomic parameters in PACG eyes, using anterior segment optical coherence tomography (SS ASOCT) device
- Trial name
- NCT05332665
- Testing
- AS-OCT, YAG laser PI
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Minia University
Glaucoma, Angle-Closure, Ocular Hypertension
A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma
To demonstrate that the intraocular pressure(IOP)-lowering efficacy of Travoprost (0.004%) is equal or better than that of Latanoprost 0.005% in patients with chronic angle-closure glaucoma.
- Trial name
- NCT00051181
- Testing
- Travoprost (0.004%), Latanoprost (0.005%)
- Where
- 2 sites in United States, Australia
- Sponsor
- Alcon Research
Primary Angle Closure Glaucoma
The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province
BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system.
- Trial name
- NCT06252246
- Testing
- Phacoemulsification machine
- Where
- Thailand
- Volunteers
- 121 people
- Sponsor
- Phanatnikhom Hospital
Glaucoma
ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function
The aim is to determine which approach, immediate argon laser peripheral iridoplasty or conventional systemic medical treatment efficiently breaks acute angle closure attack without consequent visual morbidities.
- Trial name
- Iridoplasty (NCT00485238)
- Testing
- Argon laser Iridoplasty, Intravenous acetazolamide
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Glaucoma, Angle-Closure
Study on Ex-PRESS Implantation Combined With Phacoemulsification in Primary Angle-closure Glaucoma
Primary angle-closure glaucoma (PACG) is common, phacotrabeculectomy is associated with a significant risk of complications.The Ex-PRESS shunt was introduced as a modification to trabeculectomy, with the theoretical advantages of…
- Trial name
- PACG (NCT03323138)
- Testing
- Ex-PRESS and phacoemulsification
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wenzhou Medical University
Glaucoma
Will Listening to Music Make it Easier to Take a Visual Field Test?
The purpose of this study is to examine if there is a difference between glaucoma patients having background music and not having background music before visual field testing.
- Trial name
- NCT01027039
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Angle Closure Glaucoma
Laser Iridotomy Versus Phacoemulsification in Acute Angle Closure
This is a randomised controlled clinical trial to compare laser peripheral iridotomy (LPI) and primary phacoemulsification with intra-ocular lens implantation (phaco/IOL) in the treatment of acute primary angle-closure glaucoma…
- Trial name
- NCT00350428
- Testing
- Laser Preipheral Iridotomy and phacoemulsification
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- Singapore National Eye Centre
Primary Angle Closure
Primary Angle Closure Glaucoma and Aqueous Dynamics
The aim of the study is to determine which is the best treatment for people with cataract and primary angle closure (PAC).In PAC, apposition of the iris tissue to the drainage channels (Trabecular Meshwork-TM) of the eye results…
- Trial name
- NCT00719290
- Testing
- Phacoemulsification (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5), Phacoemulsification and goniosynechialysis (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Angle Closure Glaucoma, Glaucoma
Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies
Purpose: To evaluate short-term angle opening after argon peripheral iridoplasty using AS-OCT and to report its complications at 1-week and 1-month follow up in patients that did not achieve a satisfactory clinical angle opening…
- Trial name
- ALPIECA (NCT02199158)
- Testing
- Argon Laser Peripheral Iridoplasty
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Primary Angle-Closure Glaucoma
The Multi-Omics Analysis of Lens Zonule Relaxation in The PACG Pathogenesis
Compared with primary angle-closure glaucoma (PACG) patients without zonular laxity and the control group, there are differentially expressed molecules in PACG patients with zonular laxity, and a potential mechanistic network can…
- Trial name
- NCT07539675
- Testing
- No Additional Experimental Intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhongnan Hospital
Glaucoma, Angle-Closure
Lens Extraction Combined With Goniosynechialysis Versus Trabeculectomy
To compare the effectiveness of lens extraction combined with goniosynechialysis and trabeculectomy in treating advanced angle-closure glaucoma.
- Trial name
- NCT04703712
- Testing
- Lens extraction combined with goniosynechialysis, Trabeculectomy surgery
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Primary Angle-closure Glaucoma
Kahook Dual Blade Goniotomy in Chronic Primary Angle-Closure Glaucoma
This prospective randomized controlled trial, conducted by the Ophthalmology Department of Peking University People's Hospital, aims to compare the intraocular pressure (IOP)-lowering efficacy and safety of two surgical…
- Trial name
- NCT07517302
- Testing
- Kahook Dual Blade (KDB) goniotomy, phacoemulsification with intraocular lens implantation combined with goniosynechialysis
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Peking University People's Hospital
Primary Angle Glaucoma Closure Suspect
Superior vs Temporal Laser Peripheral Iridotomy in Primary Angle Closure Suspects (PACS)
Basic Study Design: Prospective, randomized, single-center, single-blinded study to compare dysphotopsias and pain recollection immediately 2 weeks, and 3 months after LPI in PACS patients who have a clear indication for…
- Trial name
- NCT04741919
- Testing
- Yag Laser peripheral Iridotomy
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre