Clinical trials: Anesthesia Spinal
Anesthesia
Comparison of Total Intravenous Anesthesia Methods in Spinal Surgery (TIVA)
This study aims to compare the effects of the classical Total Intravenous Anesthesia (TIVA) method and multimodal anesthesia protocols created by adding lidocaine and ketamine infusions on postoperative pain management, opioid…
- Trial name
- TIVA (NCT06781177)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Cesarean Sections
Thoracic vs Lumbar Spinal Anesthesia for Cesarean Delivery
This randomized controlled trial aims to compare the effects of thoracic segmental spinal anesthesia and conventional lumbar spinal anesthesia on postoperative recovery in patients undergoing elective cesarean section.
- Trial name
- NCT07567612
- Testing
- Thoracic Segmental Spinal Anesthesia, Lumbar Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital
Analgesia, Postoperative Pain, Acute
Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier…
- Trial name
- NCT06183528
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Umraniye Education and Research Hospital
Preeclampsia, Spinal Anesthesia-Induced Hypotension
Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in Preeclampsia
This study compares the efficacy and safety of intravenous dexamethasone versus intravenous ondansetron in preventing low blood pressure (hypotension) following spinal anesthesia in pregnant women with preeclampsia undergoing…
- Conditions
- Preeclampsia, Spinal Anesthesia-Induced Hypotension, Cesarean Section
- Trial name
- NCT07793760
- Testing
- Dexamethasone, Ondansetron
- Volunteers
- 110 people
- Sponsor
- Assiut University
Anesthesia
Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
Sternum midline incision can offer better view under open-heart surgery and bigger operating space, and therefore it has been widely used in most cardiac surgery.
- Trial name
- NCT06469073
- Testing
- Transversus thoracic muscle plane block or Erector spinal plane block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Le Yu
Neuraxial Anesthesia Charting
Tracking Attempts of CSE, Epidural and Spinal Insertions (TRACES)
The goal of this study is to compare observed neuraxial (Epidural, spinal, combined spinal-epidural) insertion attempts with actual documented attempts in anesthesia providers (staff, residents and fellows) at one maternal…
- Trial name
- TRACES (NCT04862611)
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia
Evaluating the Use of 0.5 and 0.75 MAC Desflurane in Patients Undergoing Spinal Surgery
Background: Somatosensory- (SSEPs) and motor-evoked potentials (MEPs) are commonly used as an intraoperative neurophysiologic monitoring tool to detect aberrations to the spinal cord integrity during spinal surgery.
- Trial name
- NCT04717102
- Testing
- 0.5 MAC desflurane, 0.75 MAC desflurane, 1.0 MAC desflurane
- Where
- Singapore
- Volunteers
- 34 people
- Sponsor
- Changi General Hospital
Remimazolam, Spinal Anesthesia
The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal Anesthesia
The goal of this clinical trial is to compare the effect of remimazolam and dexmedetomidine on the incidence of hypotension during spinal anesthesia in adult patients.
- Trial name
- NCT05935657
- Testing
- Remimazolam, Dexmedetomidine
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Gabapentin, Tramadol
Preemptive Oral Gabapentin and Tramadol on Postoperative Pain After Knee Arthroscopy
The aim of this study to evaluate the effect of preemptive oral gabapentin versus tramadol on postoperative pain after knee arthroscopy under spinal anesthesia.
- Conditions
- Gabapentin, Tramadol, Postoperative Pain, Knee Arthroscopy
- Trial name
- NCT06112223
- Testing
- Gabapentin, Tramadol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Anesthesia; Functional
Effects of Analgesics in Cesarean Section Elective
Two approved treatments for spinal anesthesia will be compared in women undergoing cesarean section. It is usual to perform cesarean sections using spinal anesthesia with a local anesthetic (bupivacaine) plus some opioid, such as…
- Trial name
- CES (NCT03386630)
- Testing
- Hyperbaric bupivacaine+Sufentanil, Hyperbaric bupivacaine+Morphine
- Where
- Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Pain, Postoperative
Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine
The goal of this study's clinical trial is to compare in post-operative analgesic effectiveness of wound infiltration using bupivacaine, tramadol, and tramadol plus bupivacaine in patients undergoing elective cesarean section…
- Trial name
- NCT06076707
- Testing
- bupivacain-tramadol
- Where
- Ethiopia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Wollo University
Hip Arthroplasty, Knee Arthroplasty
Anaesthesia for Hip and Knee Arthroplasty (SPIGA)
Beneficial and harmful effects of spinal versus general anaesthesia in patients undergoing hip and knee arthroplasty.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia, General Anesthesia
- Trial name
- SPIGA (NCT07834242)
- Testing
- Spinal anaesthesia, General anaesthesia
- Volunteers
- 3,000 people
- Sponsor
- Zealand University Hospital
Laparoscopic Donor Nephrectomy, Perioperative Pain Management
Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor
This study aims to compare the effectiveness of spinal anesthesia adjuvant and quadratus lumborum block on the opioid requirement and perioperative pain on patients undergoing laparoscopic kidney transplant donor.
- Trial name
- NCT06764667
- Testing
- Spinal anesthesia adjuvant, Quadratus Lumborum Block (QLB), General Anesthesia
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Headache Disorders, Central Nervous System Diseases
Is Sphenopalatine Ganglion Block Treatment Effective on Postspinal Headaches
This study evaluates effect of sphenopalatine ganglion block in post dural puncture headache. Half of participants will receive standard supportive treatment and other half of patients will be performed sphenopalatine ganglion…
- Trial name
- SPG (NCT03512977)
- Testing
- sphenopalatine ganglion block, conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Derince Training and Research Hospital
Geriatric Patients, Efficacy, Self
Median and Paramedian Approach in Spinal Anesthesia
Spinal anesthesia (SA) is frequently used as anesthesia in many surgeries such as lower abdominal, inguinal, urogenital, rectal and lower extremities.
- Trial name
- NCT03750877
- Testing
- median approach, paramedian approach
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Vomiting, Nausea
Exteriorized Versus In Situ Uterine Repair at Cesarean Delivery
This study was undertaken to compare the two techniques (exteriorized vs in situ) of uterine repair with respect to patient comfort, hemodynamic changes, surgical time and blood loss, in patients undergoing elective CD under a…
- Conditions
- Vomiting, Nausea, Pain, Hypotension
- Trial name
- NCT00452972
- Testing
- Spinal Anesthesia
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Cesarean Section Complications, Spinal Anesthesia
Three Protocols for Phenylephrine Administration in Cesarean Delivery
The investigators will compare variable infusion of phenylephrine (at a starting rate of 0.75 mcg/Kg/min) with fixed rate (0.75 mcg/Kg/min which will stop of reactive hypertension occurred) and single shot (1.5 mcg/Kg)…
- Trial name
- NCT03302039
- Testing
- Single shot phenylephrine, Fixed infusion phenylephrine., Variable infusion phenylephrine.
- Where
- Egypt
- Volunteers
- 217 people
- Sponsor
- Cairo University
Cesarean Section Complications
Effects of Intrathecal Midazolam (1mg) With Hyperbaric Bupivacaine 0.5% (15mg) for Spinal Anesthesia for C-section
This study evaluates the effects of intrathecal midazolam (1 mg) combined with hyperbaric bupivacaine 0.5% (15 mg) for spinal anesthesia in cesarean section patients.
- Trial name
- NCT06748794
- Testing
- group 1
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Superior University
Postoperative Pain
Effect of TAP Block on Time Required for First Analgesic Dose After Cesarean Cection Under Spinal Anesthesia
While opioids are the mainstay for post-operative analgesia after caesarean section, they are associated with various side effects.
- Trial name
- NCT04623632
- Testing
- Transversus abdominus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams Maternity Hospital
Spinal Anesthesia
Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
Patients undergoing total knee arthroplasty with spinal anesthesia are often sedated to reduce patient discomfort due to large noises during surgery and also to reduce anxiety.
- Trial name
- NCT03322098
- Testing
- Atropine, Glycopyrrolate
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University