Clinical trials: Anesthesia, pill or tablet or capsule or oral, open to volunteers
Spinal Hypotension, Vasopressor
Caffeine and Prophylactic Noradrenaline Requirement During Cesarean Delivery
Spinal anesthesia is the preferred regional technique in obstetric practice because it provides high maternal satisfaction and eliminates the need for airway manipulation.
- Trial name
- NCT07655245
- Testing
- Caffeine (200 mg)
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Lung Cancers, Peripheral Pulmonary Nodules
General Anesthesia vs Conscious Sedation for Radial Endobronchial Ultrasound
The endoscopic investigation of lung lesions is experiencing significant growth with the increasing number of lung cancer screening programs.
- Trial name
- RESSOURCE (NCT06950515)
- Testing
- Peripheral EBUS under Concious sedation, Peripheral EBUS under General Anesthesia
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Recall, Perceived Applicability
Recall and Perceived Applicability of Ganzouri Airway Scoring System Versus LEMON Score for Airway Assessment Among Anesthesia Residents
Our aim is to compare the recall and perceived clinical applicability of Ganzouri airway scoring system versus LEMON score for airway assessment from residents' perspective.
- Conditions
- Recall, Perceived Applicability, Ganzouri Airway Scoring System, LEMON Score
- Trial name
- NCT07841392
- Testing
- Ganzouri Airway Scoring System, LEMON Score
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Anesthesia, Pain
Anesthetics and Analgesics in Children
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
- Trial name
- ANA01 (NCT03427736)
- Testing
- Ketorolac Tromethamine, Hydromorphone, Ketamine
- Where
- 13 sites in United States, Canada
- Volunteers
- 551 people
- Sponsor
- Chi Dang Hornik
Anesthesia, Supraglottic Airway Efficiency
Clinical Efficacy Evaluation of Supraglottic Airway Device SafeLM™ in Paediatric Population
The goal of this interventional study is to evaluate the clinical efficacy of SafeLM™, a video laryngeal mask airway device in paediatric population. The main questions it aims to answer are: 1.
- Conditions
- Anesthesia, Supraglottic Airway Efficiency, Paediatric Airway Management
- Trial name
- NCT07266389
- Testing
- SafeLM™ as the airway management device during general anaesthesia
- Where
- 2 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Pediatric Anesthesia, Premedication
Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery
This prospective, three-arm study aims to evaluate the effects of different oral premedication regimens on venipuncture tolerance in pediatric patients undergoing ambulatory surgery.
- Trial name
- NCT07410078
- Testing
- Oral Midazolam Premedication, Oral Midazolam plus Ibuprofen Premedication, Oral Midazolam plus Ketamine Premedication
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Coughing Responses at Tracheal Extubation, Breathing Patterns
Endotracheal Tube Intolerance and Respiratory Airflow Perception
This is a case-control study designed to enroll 224 patients who will undergo tracheal intubation for general anesthesia in the operating rooms of Peking University People's Hospital between July 20, 2026, and October 31, 2026.
- Trial name
- NCT07759284
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Post Operative Analgesia, Tonsillectomy With or Without Adenoidectomy
Preoperative High-Dose Oral Paracetamol for Postoperative Analgesia in Children Undergoing Tonsillectomy"
This randomized clinical trial compares two different preoperative doses of oral paracetamol (acetaminophen) in children undergoing elective tonsillectomy.
- Trial name
- NCT07463482
- Testing
- Paracetamol (acetaminophen)
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Thammasat University
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
General Anesthesia
Scale for Evaluating Oral and Pharyngolaryngeal Symptoms After General Anesthesia
More than 320 million surgical procedures are performed worldwide each year, and most of these procedures are performed under general anesthesia.
- Trial name
- NCT06755853
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Nuh Naci Yazgan University
Total Hip Arthroplasty (THA)
Effects of Combined Pericapsular Nerve Group (PENG) and Lateral Femoral Cutaneous Nerve (LFCN) Blocks on Anaesthetic Requirements and Electroencephalographic Depth of Anaesthesia During Total Hip Arthroplasty
This prospective, randomized controlled trial aims to evaluate the effects of combined pericapsular nerve group (PENG) and lateral femoral cutaneous nerve (LFCN) blocks on intraoperative anaesthetic consumption and…
- Trial name
- PENG-LFCN-EEG (NCT07903740)
- Testing
- Combined Pericapsular Nerve Group (PENG) and Lateral Femoral Cutaneous Nerve (LFCN) Block, EEG-Guided General Anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kocaeli City Hospital
Major Depression
Study of Psilocybin Under Anesthesia Controlled by EEG
Major depressive disorder (MDD) affects millions of Americans and remains difficult to treat. Psilocybin, a psychedelic compound, has shown promise for reducing depression symptoms, but a key challenge in psychedelic research is…
- Trial name
- SPACE (NCT07479550)
- Testing
- Psilocybin (Usona Institute), Propofol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Bacterial Transmission, Intubation Intratracheal
ORAL-PROTECT I: Oral Asepsis Preventing Transmission During Intubation
Postoperative respiratory complications, such as bacterial pneumonia, are common and serious problems after general anesthesia. They can lead to longer hospital stays, more complications, and increased mortality.
- Conditions
- Bacterial Transmission, Intubation Intratracheal, Chlorhexidine
- Trial name
- ORAL-PROTECT I (NCT07669064)
- Testing
- Preoperative oral decontamination with chlorhexidine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Ulm
Spinal and Epidural Anaesthesia-Induced Headache During Pregnancy
Establishment of a Predictive Model for Post-dural Puncture Headache
The goal of this clinical trial is to establish a predictive model for post-dural puncture headache. The main questions it aims to answer are: Changes in intracranial pressure after spinal puncture (or lumbar puncture).
- Trial name
- NCT06800859
- Testing
- Supplement fluids
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yilin Zhao
Postdural Puncture Headache (PDPH)
Oral Gabapentin Versus Intravenous Neostigmine/Atropine Versus Combination of Both for Prevention of PDPH
Post-dural puncture headache (PDPH) is a major complication of neuraxial anaesthesia. Pain is intense, frontal, throbbing, and radiates to the occiput; it is more severe when standing and less severe when lying down.
- Trial name
- NCT07916116
- Testing
- treatment of Postdural puncture headache
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Regional Anesthesia, Hip Arthroplasty
SFIB vs PENG Block in the Anesthesia for Total Hip Replacement
Total hip replacement is one of the most common orthopedic operations. According to statistical studies, more than 1 million of such surgical interventions are performed annually in the world.
- Trial name
- NCT07061223
- Testing
- SFIB, PENG block, Patient control analgesia
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Ultrasonographic, Mallampati Score
Combined Ultrasonographic Skin-to-Epiglottis Distance With Modified Mallampati Versus Modified Mallampati Score Alone in Predicting Difficult Laryngoscopy During Tracheal Intubation Under General Anesthesia
This study will evaluate how well an ultrasound measurement of the distance from the skin to the epiglottis, when combined with the modified Mallampati score, can predict difficult laryngoscopy in adult patients undergoing…
- Conditions
- Ultrasonographic, Mallampati Score, Mallampati Score, Difficult Intubation, Videolaryngoscope, Tracheal Intubation
- Trial name
- NCT07315256
- Testing
- Ultrasound-Guided Skin-to-Epiglottis Distance Measurement, Clinical Airway Assessment With Modified Mallampati Score
- Volunteers
- 160 people
- Sponsor
- Assiut University
Airway Complication of Anesthesia
Airway US in Predicting Difficult Pediatric Laryngoscopy
The hypothesis of this study is that ultrasound measurements may improve the preoperative detection of difficult laryngoscopy (DL) in pediatrics.
- Trial name
- AirwayUS (NCT06892405)
- Testing
- SonoSite™ S Series ultrasound
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Assiut University
Adenotonsillectomy, Preoperative Anxiety
Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery
This study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy.
- Conditions
- Adenotonsillectomy, Preoperative Anxiety, Surgical Stress Response, Postoperative Pain
- Trial name
- Timing-Midazol (NCT07622641)
- Testing
- Midazolam (Oral), Midazolam (Intravenous)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzurum City Hospital