Clinical trials: Anesthesia,General
Pulmonary Atelectasis
Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants
Investigators hypothesized that lung ultrasound-assisted recruitment maneuver would be beneficial in mechanically ventilated infants compared to those who did not receive lung ultrasound and alveolar recruitment maneuver.
- Trial name
- NCT02584023
- Testing
- Lung ultrasound
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Anesthesia Recovery Period
Minimum Current for Train-of-four Monitoring
Neuromuscular monitoring during general anesthesia is important to make sure adequate muscle relaxation during operation and adequate recovery of muscle power and spontaneous breathing during emergence from general anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Neuromuscular Blockade
- Trial name
- NCT04581720
- Testing
- Train-of-four (TOF)
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Airway Management, Tracheal Intubation
Effect of Night Shift Versus Daytime Duty on Tracheal Intubation Complications and Duration in Surgical Patients
Airway management is one of the most critical steps of anesthesia, and its complications can be life-threatening. Reduced staffing, differences in personnel experience, and physical and mental fatigue during off-hours (evenings…
- Conditions
- Airway Management, Tracheal Intubation, Intubation Complications, General Anesthesia
- Trial name
- NCT07823179
- Testing
- Tracheal Intubation
- Volunteers
- 1,000 people
- Sponsor
- Merve Yazici Kara
Intratracheal, Dexmedetomidine
Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:
The incidence of intratracheal tube-induced laryngeal irritation, including coughing, bucking, and cardiovascular stimulation, on emergence from general anesthesia has been reported to occur in 38% and 96% of cases.
- Trial name
- NCT04385602
- Testing
- Intratracheal dexmedetomidine, Saline Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
ECT, Anesthesia
Sevoflurane in Electroconvulsive Therapy
The purpose of the study was to investigate the effects of different doses of sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles
- Trial name
- NCT01905904
- Testing
- sevorane
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Inonu University
Intertrochanteric Fractures
Blocks for Intertrochanteric Fracture Repair Surgery
This single-center open label study compares the outcomes of surgical repair of intratrochanteric fracture under general anesthetic or peripheral nerve blocks.
- Trial name
- NCT04470115
- Testing
- General anesthesia, Regional anesthesia- femoral and lateral femoral cutaneous nerve blocks
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Military Institute od Medicine National Research Institute
Post-induction Hypotension
Management of Post-Induction Hypotension in Emergency Abdominal Surgery
The goal of this clinical trial is to compare the efficacy of two vasopressors (norepinephrine vs. ephedrine) in treating hypotension in adult patients (aged 18+, ASA I-III) undergoing general anesthesia for abdominal surgical…
- Trial name
- NCT07259655
- Testing
- Ephedrine (6 mg boluses), Norepinephrine (10 µg boluses)
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- Hopital Charles Nicolle
Cognitive Deficits, Cognitive Ability, General
Childhood Anesthesia and Cognitive Function
The purpose of this study is to determine whether pediatric anesthesia is associated with long-term hippocampal dysfunction
- Trial name
- UCSF-Anes-01 (NCT01359215)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endotracheal Intubation Using Videolaryngoscope for General Anesthesia, Endotracheal Intubation Risk Assessment
Intubation in Supine Versus Lateral Position Using Different Tools of Laryngoscopy in Patients With Neck Masses
This study is aimed to compare different tools of endotracheal intubation in supine versus lateral position in patients with neck masses. Primary outcome: is time taken for intubation.
- Trial name
- NCT07507032
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Aswan University
Pain
Pain Assessment During General Anesthesia
During general anesthesia, two treatments are used : hypnotic and opioid treatment. Opioid treatment is used for pain assessment.
- Trial name
- DOLANS (NCT01303471)
- Testing
- opioid (remifentanyl)
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Electroencephalography, Anesthesia
Predictive Model in EEG for Induction and Emergence in Pediatric With Propofol
Anesthesia is essential to control pain and produce unconsciousness during surgery and other procedures during childhood. The anesthetic deepness is measured indirectly through changes in blood pressure and heart rate or can be…
- Conditions
- Electroencephalography, Anesthesia, Children, Only
- Trial name
- EEGPED (NCT03705338)
- Testing
- Electroencephalography, Propofol
- Where
- Chile
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Victor Contreras, MSN
Postoperative Pain, Postoperative Sleep Quality
The Effect of Intraoperative Use of Dexmedetomidine During the Daytime Operation vs the Nighttime Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
General anesthesia is a medically induced state of low reactivity consciousness which is similar to natural sleep. Some studies found that general anesthesia as an independent risk factor could result in a desynchronization of…
- Conditions
- Postoperative Pain, Postoperative Sleep Quality, Intraoperative Dexmedetomidine, General Anesthesia
- Trial name
- NCT03990987
- Testing
- time of receiving operation
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Shengjing Hospital
Sphenopalatine Ganglion Block, General Anesthesia
Sphenopalatine Ganglion Block as Adjuvant to General Anesthesia Regarding the Quality of Surgical Field in Trans-Sphenoidal Endoscopic Hypophysectomy
This study aims to evaluate the efficacy of ultrasound guided sphenopalatine ganglion block (SPGB) through the suprazygomatic approach in optimizing the quality of surgical field as well as its effect on postoperative pain relief…
- Conditions
- Sphenopalatine Ganglion Block, General Anesthesia, Quality of Surgical Field, Trans-Sphenoidal Endoscopic Hypophysectomy
- Trial name
- NCT07569952
- Testing
- Sphenopalatine ganglion block using bupivacaine + dexamethasone, General anesthesia
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Bradycardia, Neostigmine Adverse Reaction
0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle Relaxant
Balanced general anesthesia with neuromuscular blocking agents has been widely used for surgery.. At the end of surgery, neostigmine has been given for the reversal of neuromuscular blocking agents with several adverse effects…
- Conditions
- Bradycardia, Neostigmine Adverse Reaction, Adverse Reaction to Belladonna or Atropine
- Trial name
- NCT02186132
- Testing
- Atropine 0.6 mg, Atropine 1.2 mg
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Intravenous Anesthesia, Cholelithiasis
Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy
The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy.
- Trial name
- REMIPROP-LOC (NCT07717684)
- Testing
- Remimazolam, Propofol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal de Sergipe
Intubation, Endotracheal, Anesthesia, General
A Comparison of Two GlideScope Intubation Techniques
The aim of this study is to compare the hemodynamic response to tracheal intubations using the standard technique versus the alternative GS intubation technique.
- Trial name
- NCT01865643
- Testing
- GlideScope
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Evaluation of Success Rate, Airway Leak Pressure
Evaluation of Supraglottic Airway Devices in Children and Comparison to Historic Control
The supraglottic airway device LMA Supreme has recently been introduced for pediatric patients. The investigators will prospectively evaluate success rate and airway leak pressure in everyday's clinical pediatric anesthesia…
- Conditions
- Evaluation of Success Rate, Airway Leak Pressure, Side Effects of LMA Supreme in Pediatric Patients Undergoing General Anesthesia
- Trial name
- NCT01625858
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Dental Phobia, Disabilities Multiple
Evaluation of Implant Therapies Performed Under General Anesthesia in Patients With Specific Dental Needs
Implant placement is the solution of choice for replacing missing teeth in a fixed way. However, dental practitioners and surgeons are reluctant to place implants in the population of patients with special needs.
- Conditions
- Dental Phobia, Disabilities Multiple, Complex Medical Health Condition
- Trial name
- NCT05153538
- Where
- France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Clermont-Ferrand
Depression, Anxiety
Effect of General and Non-general Anesthesia on Perioperative Depression or Anxiety
Perioperative depression and/or anxiety play a critical role in patient presentation, satisfaction and outcomes. The aim of this study is to assess the level of perioperative depression and/or anxiety in patients with…
- Trial name
- NCT05315648
- Testing
- anesthesia approach (general anesthesia or non-general anesthesia)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
General Anesthesia, Laparoscopic Cholecystectomy
Intrinsic PEEP During Mechanical Ventilation of Patients With Obesity
It is demonstrated that expiratory flow limitation and as a consequence, intrinsic positive end-expiratory pressure (PEEP) is present in grossly obese subjects especially in the supine position.
- Trial name
- NCT01267916
- Testing
- RR 6 + 0, RR 10 + 0, RR 16 + 0
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul Medical Center