Clinical trials: Anesthesia, Spinal
Hypotension
Hemodynamic Impact of Hyperbaric Versus Isobaric for Spinal Anesthesia During Cesarean Delivery
The purpose of this study is to compare the frequency of hypotension between hyperbaric anesthetics and isobaric anesthetics during cesarean section and determine whether continuous infusion of phenylephrine is effective in…
- Trial name
- NCT02802683
- Testing
- Bupivacaine, Levobupivacaine, Phenylephrine
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Obesity, Hip Arthroplasty
Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients
General anesthesia (GA) and paralysis are factors which facilitate atelectasis formation, especially in obese patients. Spontaneous breathing can reduce the amount of atelectasis.
- Conditions
- Obesity, Hip Arthroplasty, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT01382927
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Technische Universität Dresden
Pain, Postoperative, Inguinal Hernia Unilateral
Intrathecal Morphine and Transversalis Fascia Plane Block for Analgesia After Open Inguinal Hernia Repair
Inguinal hernia is a common surgical condition, and open inguinal hernia repair may be associated with significant postoperative pain.
- Conditions
- Pain, Postoperative, Inguinal Hernia Unilateral, Intrathecal Morphine, Transversalis Fascia Plane Block
- Trial name
- NCT07826741
- Testing
- Intrathecal Morphine Group, Transversalis Fascia Plane Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Pregnancy, Cesarean Section
Different Approaches to Maternal Hypotension During Cesarean Section
The aim of this study is to compare two different therapeutic approaches to blood pressure reduction: pharmacological vs. non-pharmacological.
- Conditions
- Pregnancy, Cesarean Section, Anesthesia,Spinal, Hypotension
- Trial name
- NCT00991627
- Testing
- Bupivacaine, Morphine, Lactated Ringer's solution
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Parma
Post Anaesthetic Shivering
Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering
Post Anaesthetic Shivering is a common complication of Subarachnoid block. It is graded based on it's severity and has been known to cause various problems like patient's discomfort, hypoxia, change in hemodynamic variables of…
- Trial name
- NCT02441673
- Testing
- Nefopam, Tramadol, Metoclopramide
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Lagos State Health Service Commission
Benign Prostate Hyperplasia, Bladder Tumor
Effective Dose of Dexmedetomidine for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia With or Without Fentanyl by Age Groups: Randomized Comparative Study
Recently many studies reported that intraoperative dexmedetomidine administration undergoing spinal anesthesia give a satisfactory sedation in elderly patients and cause less respiratory depressions compared other sedatives(e.g.
- Trial name
- NCT01665586
- Testing
- dexmedetomidine
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Hip Fractures, Hemodynamic Stability
Hemodynamic Safety of Levobupivacaine vs Bupivacaine in Patients Over 65 Years Undergoing Hip Surgery
The altered hemodynamics, and therefore the arterial hypotension is the most prevalent adverse effect after subarachnoid anesthesia.
- Trial name
- NCT03843970
- Testing
- Levobupivacaine Hydrochloride 0.5%, Isobaric bupivacaine 0.5%
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Clínico Universitario de Valencia
Hypotension, Pregnancy
ET50 With Fentanyl for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50-Fent (NCT01896960)
- Testing
- Bupivacaine with 15 micrograms of fentanyl
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Spine Fusion, Locoregional Anaesthesia
PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block for Postoperative Pain Management in Spinal Fusion
This is a prospective observational study conducted at the trauma center of Città della Salute e della Scienza of Turin. The aim of the study is to compare two local regional anesthesia techniques in multimodal analgesia for…
- Conditions
- Spine Fusion, Locoregional Anaesthesia, Intrathecal Anesthesia, Erector Spina Plan Block
- Trial name
- POPSSCOP (NCT07245524)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Procedural Sedation
Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative…
- Trial name
- NCT04873596
- Testing
- Nebulized dexmedetomidine, Nebulized midazolam
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Supine Hypotensive Syndrome
Hemodynamic Management in Women With SHS
Supine hypotensive syndrome often occurs following spinal anesthesia for cesarean delivery.In our study we base the regulation and drug administration both on the regular monitor and on a novel monitor which reflects upon the…
- Trial name
- NCT05341362
- Testing
- LiDCOrapid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China Medical University, China
Combined Spinal Epidurai Anesthesia, Lower Extremity Surgery
the Relationship Between Vertebral Body Length, Subarachnoid Space Width and Block Level
Spinal anesthesia technology has been widely used in various surgeries and multi-mode analgesia. Spinal ultrasound imaging has been proved to be a reliable tool for evaluating spinal parameters.
- Trial name
- NCT05201261
- Testing
- ltrasonic measure
- Volunteers
- 50 people
- Sponsor
- Shengjing Hospital
Femoral Neck Fracture
Ropivacaine Hypobaric Spinal Anaesthesia in Traumatic Hip Surgery
This is a prospective, monocentric, randomized study, comparing the effectiveness and tolerance of four different dosages of hypobaric ropivacaine for unilateral spinal anaesthesia during traumatic femoral neck surgery in the…
- Trial name
- NCT01005550
- Testing
- 6 mg of ropivacaine, 8 mg of ropivacaine, 10 mg of ropivacaine
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Caesarean Section, Pain, Acute
Subarachnoid Block With Ultrasound-Guided Transversalis Fascia Plane Block for Cesarean Section
Postoperative pain management is critical for the fulfillment of the maternal duties. The transversalis fascia plane (TFP) block provides adequate postoperative analgesia in the T12 and L1 dermatomes.
- Trial name
- NCT04172727
- Testing
- Bupivacaine Hcl 0.25% Inj, saline 0.9%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pain
Effect of Shotblocker on Procedure-related Pain, Satisfaction and Comfort in Patients Receiving Spinal Anesthesia
Although spinal anesthesia, which is increasingly common today, is a fast and reliable method, many patients are afraid of this procedure due to their fear of needles.
- Trial name
- NCT06163027
- Testing
- Shotblocker, Shotblocker(Plasebo)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Postoperative Pain, Lower Limb Injury
Block Duration After Spinal Block and iv Dexamethasone.
It has been largely demonstrated that iv dexamethasone prolongs the duration of analgesia after peripheral nerve block. However, data are missing regarding the duration of analgesia after spinal block.
- Trial name
- NCT03527576
- Testing
- Dexamethasone, NaCl 0.0308 MEQ/ML Injectable Solution
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Eric Albrecht
Pregnant, High Altitude
The Effect of Different Altitude Levels on Spinal Anesthesia in Cesarean Section Surgery
The aim of the researchers in this prospective study is to determine the differences, if any, in terms of anesthetic parameters among pregnant women who live at different altitudes and undergo cesarean section under neuraxial…
- Trial name
- altitude (NCT05715476)
- Testing
- cesarian surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Giresun University
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Spinal Fractures, Anesthesia, Regional
Effectiveness of Erector Spinae Block in Kyphoplasty
As of October 2019, when the investigators received the approval of the ethics committee, patients who were decided to undergo kyphoplasty with vertebral compression fracture will be included in the study.
- Conditions
- Spinal Fractures, Anesthesia, Regional, Anesthetics, Local, Analgesia
- Trial name
- NCT04201678
- Testing
- CLIA Group (conventional local anesthesia infiltration), EPIAA Group (Extrapedicular infiltration anesthesia), ESP Group (Erector Spina Block)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gulhane School of Medicine
Inguinal Hernia
Local Anesthetic Infiltration VS Trasversalis Fascia Block VS Spinal Anesthesia
Propose to comparison effectiveness of blind local anesthetic infiltration with ultrasound guided Transversals Fascia Block and Spinal Anesthesia in patients undergoing to inguinal hernia repair surgery.
- Trial name
- NCT03128216
- Testing
- Blind Local Anesthetic infiltration, Transversals Fascia Block, Spinal Anesthesia
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Istituti Ospitalieri di Cremona