Clinical trials: Anesthesia, Obstetric, open to volunteers
Cesarean Section, Postoperative Recovery
Enhanced Recovery Protocol Compliance and Quality of Recovery After Cesarean Delivery
This prospective observational study will evaluate whether adherence to enhanced recovery after cesarean delivery protocols is associated with postoperative recovery quality in women undergoing elective cesarean delivery under…
- Conditions
- Cesarean Section, Postoperative Recovery, Postoperative Pain
- Trial name
- ERAC-QoR (NCT07790471)
- Testing
- Assessment of Enhanced Recovery Protocol Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center
Laparoscopic Obstetric Surgery
Total Intravenous Anesthesia (TIVA) Versus Inhalational Anesthesia at The End of Laparoscopic Obstetric Surgery Regarding Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) remain among the most common and distressing complications after general anaesthesia, with important consequences for patient comfort, satisfaction, recovery trajectories, and length of…
- Trial name
- NCT07270289
- Testing
- inhalational anaesthesia, total intravenous anesthesia (TIVA)
- Volunteers
- 98 people
- Sponsor
- Assiut University
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients
Anesthesiologists commonly administer pain relief during labor or providing anesthesia for cesarean delivery. Two main methods are used to achieve these goal: "Regional anesthesia" where the mother is given medication through a…
- Trial name
- DADB (NCT02193542)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Pain Management, Postoperative Acute Pain
Effect of Sedation After Ultrasound-Guided Spinal Anesthesia on Back Pain
This study will evaluate whether giving sedation before spinal anesthesia, when performed with ultrasound guidance, reduces the risk of developing back pain after surgery.
- Conditions
- Pain Management, Postoperative Acute Pain, Chronic Back Pain
- Trial name
- NCT07198412
- Testing
- Ultrasound-guided spinal anesthesia, Midazolam plus ultrasound-guided spinal anesthesia, Landmark-guided spinal anesthesia
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Benha University
Obstetric Pain, Anesthesia, Local
The Use of Electrical Stimulation for Determination of Epidural Catheter Placement
The aim of this study is to address the problem of epidural failure. The investigators theorize epidural failure can be due to inappropriate catheter movement and this may be related to the length of which the epidural catheter…
- Trial name
- NCT06055686
- Testing
- Electrical Epidural Stimulation Test
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Obstetric Pain
Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery
Based on randomization, patients will receive a mixture for spinal anesthesia and will be followed in the following hours for the various outcomes and for functional recovery
- Trial name
- MoFe (NCT06355271)
- Testing
- Fentanyl 1, Fentanyl2, Fentanyl 3
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Placenta Accreta Spectrum
Spinal Versus General Anesthesia in Pregnancies With Placenta Accreta Spectrum: A Retrospective Comparative Study
Placenta accreta spectrum (PAS) is a serious pregnancy complication in which the placenta grows abnormally into the uterine wall.
- Trial name
- SAGA-PAS (NCT07406841)
- Testing
- spinal anesthesia, General Anesthesia
- Volunteers
- 50 people
- Sponsor
- Gaziantep City Hospital
Obstetric Pain, Anesthesia, Local
Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric Population
Following labor, epidural or combined spinal-epidural (CSE) catheters are kept in place and deactivated. However, many women opt for procedures such as tubal ligation, which may require epidural anesthesia as a method of pain…
- Trial name
- NCT04983511
- Testing
- Electrical Epidural Stimulation Test (EST)
- Volunteers
- 40 people
- Sponsor
- Stanford University
Pregnancy, Labor and Delivery
Ropivacaine and Fentanyl for Labor Epidural Initiation
This study is being done to determine the most effective dose of medicine to use to initially provide effective pain relief within the first 30 minutes of receiving an epidural for pain labor during labor.
- Conditions
- Pregnancy, Labor and Delivery, Labor Analgesia
- Trial name
- EV90_DPE (NCT07076368)
- Testing
- Ropivacaine + Fentanyl
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Post Spinal Anesthesia Shivering
Two Doses of IV Magnesium Sulfate for Prevention of Post-Spinal Shivering
The main purpose of the study is to compare the incidence of clinically significant shivering, defined as Grade 3 or 4 on the Crossley-Mahajan shivering scale, within 60 minutes after spinal anesthesia.
- Trial name
- NCT07913828
- Testing
- Magnesium Sulfate 50 mg/kg IV, Magnesium Sulfate 30 mg/kg IV
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Suez Canal University
Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775)
Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean Section
This study compares two methods of identifying the correct intervertebral level before performing spinal anesthesia in women undergoing elective cesarean delivery.
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775), Hypotension (MeSH: D007022)
- Trial name
- USG-SPINE (NCT07789756)
- Testing
- Preprocedural ultrasound level identification, Landmark palpation level identification
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Epidural Catheterization
Ultrasound Predictors of Difficulty in Performing Epidural Anesthesia for Labor in Pregnant Patients.
This is a prospective observational study conducted at the University Hospital of Padua. The goal is to identify ultrasound markers that can help predict whether placing an epidural catheter during labor will be difficult.
- Trial name
- NCT07056166
- Testing
- epidural catheter, spine ultrasonography
- Where
- Italy
- Volunteers
- 563 people
- Sponsor
- University of Padova
Post Dural Puncture Headache
Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients
Some patients develop headache after spinal anesthesia used during cesarean section. This condition is called post-dural puncture headache (PDPH). Early identification of patients at risk may improve patient care.
- Trial name
- NCT07497945
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Kocaeli University
Labor Pain and to Reduce Pain
Does the Volume of Medication Affect the Success of Labor Epidural Analgesia
The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.
- Trial name
- EpiVol (NCT07684365)
- Testing
- administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Obstetric Pain, Anesthesia, Local
Obstetric Placement Study Using EST
Combined spinal-epidural (CSE) is an established technique for providing labour analgesia to obstetric patients which provides rapid onset but unsustained analgesia.
- Trial name
- NCT04109365
- Testing
- Electrical Epidural Stimulation Test (EST)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Labour Analgesia
Prediction of Local Anaesthetic Dosing During Labour Epidural Analgesia
Epidural analgesia is the gold standard for controlling labour pain. However, labour pain happens during neuraxial analgesia, due to anaesthetic, obstetric, maternal factors.
- Trial name
- DIANA (NCT07614516)
- Testing
- Machine-learning prediction model
- Where
- Italy
- Volunteers
- 12,500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
Ultrasound Assessment Of Gastric Volume In Pregnant Women Undergoing Elective Cesarean Section
The primary objective of this study is to compare gastric volume prior to elective cesarean section between pregnant women diagnosed with gestational diabetes mellitus (GDM) and those without GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital