Clinical trials: Anesthesia, Intravenous
Dexmedetomidine, Total Intravenous Anesthesia
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.
- Conditions
- Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
- Trial name
- DEXREM (NCT06684197)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Intravenous Anesthesia, Cholelithiasis
Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy
The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy.
- Trial name
- REMIPROP-LOC (NCT07717684)
- Testing
- Remimazolam, Propofol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal de Sergipe
Spinal (Fusion) Surgery, Total Intravenous Anesthesia
Comparison of Hemodynamic Responses During Anesthesia Induction Using Eleveld and Schnider
This randomized prospective study aims to compare the effects of two target-controlled infusion models, the Schnider and Eleveld models, on anesthetic depth and hemodynamic responses during anesthesia induction in adult patients…
- Conditions
- Spinal (Fusion) Surgery, Total Intravenous Anesthesia, Target Controlled Infusion of Propofol, Anesthesia Depth Monitoring
- Trial name
- NCT07586189
- Testing
- TCI Propofol Injection Models- Eleveld, TCI Propofol Injection Schnider
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Anesthesia Recovery, Pediatric Anesthesia
Recovery Trajectories After Propofol-Based Intravenous Anesthesia in Toddlers and Older Children
This observational study aims to compare how quickly and smoothly younger children (ages 3 to 6 years) recover from general anesthesia compared to older children (ages 6 to 12 years).
- Conditions
- Anesthesia Recovery, Pediatric Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07766629
- Volunteers
- 64 people
- Sponsor
- Assiut University
Postoperative Recovery, Inhalation Anesthesia
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated.
- Conditions
- Postoperative Recovery, Inhalation Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07123870
- Testing
- Sevofluorane, Desflurane, Total Intravenous Anesthesia(TIVA)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Venipuncture, Ultrasound
A New Landmark-formula for Cephalic Vein in Children
In children undergoing surgery, a venous access line almost always has to be placed. Through this line, medications and fluids can be administered during anesthesia or later during the hospital stay.
- Conditions
- Venipuncture, Ultrasound, Difficult Intravenous Access in Pediatrics, Pediatric Anesthesia
- Trial name
- NCT07333846
- Where
- Switzerland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexander Schmidt
Bispectral Index Monitoring, Burst Suppression
Relationship Between Induction Burst Suppression and Bispectral Index
The purpose of this study is to understand whether certain brain activity patterns that can appear at the beginning of anesthesia are related to how deep anesthesia remains during the operation.
- Conditions
- Bispectral Index Monitoring, Burst Suppression, Total Intravenous Anesthesia
- Trial name
- NCT07557433
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Amasya University
Upper Gastrointestinal Endoscopy, Topical Anesthesia
Oropharyngeoesophageal Topical Anesthesia Versus Intravenous Propofol -Ketamine Sedation for Upper Gastrointestinal Endoscopy
Esophagogastroduodenoscopy (EGD) is an essential and widely used diagnostic and therapeutic procedure in gastroenterology. EGD can be performed in association with topical anesthesia of the pharynx, intravenous anesthesia, or…
- Conditions
- Upper Gastrointestinal Endoscopy, Topical Anesthesia, Intravenous Sedation
- Trial name
- NCT07563062
- Testing
- Propofol and Ketamine Mixture (Ketofol), Modified Oropharyngeo-esophygeal Topical Anesthesia by OPETA Prototype tool
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Anesthesia, Pediatric Anesthesia
Transition From Sevoflurane to Total Intravenous Anesthesia in Pediatric Patients
his prospective, observational, exploratory, and multicenter study aims to describe the evolution of propofol effect-site concentration administered via target-controlled infusion (TCI) based on the Eleveld model-with adjustments…
- Conditions
- Anesthesia, Pediatric Anesthesia, Total Intravenous Anesthesia
- Trial name
- TSTP (NCT07644260)
- Where
- 2 sites in Argentina
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas José de San Martín
POCD - Postoperative Cognitive Dysfunction, Recovery Time
The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy
In this study, the investigators want to examine the effects of intravenous anesthetic drugs and gases on cognitive functions in the postoperative period in individuals who will undergo surgery for obesity.
- Conditions
- POCD - Postoperative Cognitive Dysfunction, Recovery Time, Postoperative Neurocognitive Disorder, Postoperative Delirium
- Trial name
- NCT07637357
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Remimazolam, Total Intravenous Anesthesia
Remimazolam TIVA-Flumazenil Antagonism in Short-duration ENT Surgeries
This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism based on whether their intraoperative BIS values were maintained below 60.
- Conditions
- Remimazolam, Total Intravenous Anesthesia, Bispectral Index
- Trial name
- TIVA (NCT07389798)
- Where
- China
- Volunteers
- 511 people
- Sponsor
- Tongji Hospital
Hypotension on Induction, Cardiac Surgery
The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery.
- Conditions
- Hypotension on Induction, Cardiac Surgery, Antihypertensive Agents, Anesthesia, Intravenous
- Trial name
- NCT07541222
- Testing
- Chronic Antihypertensive Medication Use
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Konya City Hospital
Pain Threshold, Surgery
The Effect of Remifentanil on the Objectively Measured Pressure Pain Threshold
It is a clinical study investigating the relationship between objectively measured pain threshold and the need for escalating doses of remifentanyl opioids. This study is expected to include approximately 40 participants.
- Conditions
- Pain Threshold, Surgery, Postoperative Pain, Intravenous Anesthesia
- Trial name
- NCT07568405
- Testing
- Pressure pain theshold measured under remifentanil (ultiva®) infusion, Postoperative PCA IV morphine (Sterop®) consumption and adverse events history
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Postoperative Sleep Quality, Nasal Septum Deviation
Anesthesia Type and Postoperative Sleep Quality in Septoplasty
This prospective observational study aims to evaluate the association between routinely applied anesthesia techniques and postoperative sleep quality in adult patients undergoing septoplasty.
- Conditions
- Postoperative Sleep Quality, Nasal Septum Deviation, Septoplasty, Total Intravenous Anesthesia
- Trial name
- ANES-SLEEP (NCT07325799)
- Where
- Turkey (Türkiye)
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Cesarean Section, Anesthesia, General
Comparing Inhalational Anesthesia and TIVA on Maternal and Neonatal Hemodynamics in Elective Cesarean Section
This prospective, double-blind, randomized controlled trial compares the effects of total intravenous anesthesia (TIVA) versus sevoflurane-based inhalational anesthesia on maternal hemodynamics, depth of anesthesia, and early…
- Conditions
- Cesarean Section, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- NCT07513870
- Testing
- Propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Medipol University
Anesthesia, Intravenous, Hemodynamic Stability
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery…
- Conditions
- Anesthesia, Intravenous, Hemodynamic Stability, Gynecologic Surgery
- Trial name
- By_HD (NCT07251101)
- Testing
- Remimazolam, Propofol
- Where
- 2 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- Ilsan Cha hospital
Elderly, Surgery
Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio
The impact of anesthesia depths on early postoperative neurocognitive complications after total intravenous anesthesia (TIVA) remains controversial.
- Conditions
- Elderly, Surgery, Depth of Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07479719
- Testing
- Light anesthesia, Deep anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Acute Pain, Chronic Pain
Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
Research suggests that the type of anesthesia used for surgery may affect intraoperative stress hormone levels. There is also data to support that an increased level of stress hormones leads to increased pain after surgery.
- Conditions
- Acute Pain, Chronic Pain, Hernia, Anesthesia, Intravenous
- Trial name
- NCT02527083
- Testing
- Propofol, Sevoflurane, Remifentanil
- Volunteers
- 10 people
- Sponsor
- VA Pittsburgh Healthcare System
Anesthesia, Sedation
EEG-Guided Sedation in ERCP Procedures
Patients undergoing ERCP have a wide range from patients with poor general condition and septicaemia findings to outpatients who come as day patients without any other additional disease.
- Conditions
- Anesthesia, Sedation, Sedation Complication, Anesthesia, Intravenous
- Trial name
- ERCP-EEG (NCT06866886)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent