Clinical trials: Analgesia Assessment, open to volunteers
Postoperative Analgesia After Unilateral Hip Arthroplasty
Efficacy and Safety of TRD205 Tablets for Postoperative Analgesia in Unilateral Total Hip Arthroplasty (Phase IIb)
This is a phase IIa, multicenter ,randomized, double-blind, Double-Dummy, Active- and placebo-controlled study designed to evaluate the efficacy, safety and kinetic characteristics of TRD205 tablets for postoperative analgesia…
- Trial name
- TRD205 (NCT07543796)
- Testing
- TRD205 Tablets, oral; 400 mg initial dose, then 200 mg q12h for 3 doses; total 4 doses, TRD205 Tablets, oral; 800 mg initial dose, then 400 mg q12h; total 4 doses, TRD205 Tablets, oral; 1200 mg initial dose, then 600 mg q12h; total 4 doses
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Tide Pharmaceutical Co., Ltd
Urolithiasis, Kidney Stones
Pain Control During ESWL Using Non-Opioid Analgesics
This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL).
- Conditions
- Urolithiasis, Kidney Stones, Ureteral Stones
- Trial name
- ESWL-PAIN (NCT07512297)
- Testing
- Ibuprofen (Brufen®), Paracetamol (drug), Tenoxicam
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- University of Gaziantep
Emotion Management Skills, Lifestyle, Healthy
The Impact of Enhanced Music & Natural Visuals on Emotional Health
The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress.
- Conditions
- Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
- Trial name
- NCT07676110
- Testing
- soundBrilliance software application - Emotional Health
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- soundBrilliance LLC
Postoperative Analgesia After Unilateral Hallux Valgus Correction Surgery
To Evaluate the Safety, Efficacy and Kinetic Characteristics of TRD205 Tablets for Postoperative Analgesia After Unilateral Hallux Valgus Orthopedic Surgery
This is a multicenter, randomized, double-blind, placebo-controlled phase Ib study designed to evaluate the safety, efficacy and PK of TRD205 tablets administered orally .
- Trial name
- TRD205 (NCT07121023)
- Testing
- TRD205 tablets
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Beijing Tide Pharmaceutical Co., Ltd
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Labour Pain
Spoken Animation for Labour Epidural
The purpose of this study is to evaluate a new animated information film as a tool for introducing the concept of epidural as a method of labour pain relief to expectant women.
- Trial name
- SALE (NCT07202221)
- Testing
- Participant views Epidural animation before reading gold standard written information, Participant receives current gold standard written information alone
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Pain and Anxiety in Children With MIH
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with…
- Trial name
- NCT07374354
- Testing
- ibuprofen 100mg/ml oral suspension syrup
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- October University for Modern Sciences and Arts
Postoperative Pain
Clinical Pharmacist-Led Perioperative Pain Management in Orthopedic Surgery: An Effectiveness Evaluation
This study aims to evaluate the effectiveness of a clinical pharmacist-led perioperative pain management model in orthopedic surgery. It is a randomized controlled trial involving patients undergoing major orthopedic procedures.
- Trial name
- NCT07688486
- Testing
- Clinical Pharmacist-Led Pain Management, Standard Perioperative Care
- Volunteers
- 600 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Post Operative Pain, Analgesia
Evaluation of Postoperative Pain Control in Ear Surgery
Middle ear surgery is the most popular procedure in ear, nose and throat surgery. Increased sympathetic stimulation after surgery can activate the sympathetic system, causing hypertension and increased heart rate.
- Trial name
- NCT06869967
- Testing
- Auricularis Magnus Nerve Block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kocaeli University
Pain, Chronic Pain
Evaluation of an Opioid Stewardship Program in Non-Cancer Patients
The objective of this prospective, non-randomized clinical trial is to evaluate the effectiveness of a pharmacist-led Opioid Stewardship Program (OSP) in outpatient adults with chronic non-cancer pain.
- Conditions
- Pain, Chronic Pain, Opioid Analgesia, Opioid Use
- Trial name
- NCT07102446
- Testing
- Opioid Stewardship Program
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Korea University Guro Hospital
ENT Cancers
Evaluation of the Superficial Cervical Plexus Block in Oncological Throat and Neck Surgery
This national, prospective, multicenter, randomized study aims to reduce the amount of intravenous morphine (titration + PCA morphine) during the first 24 postoperative hours via a locoregional anesthesia technique in patients…
- Trial name
- BCS-ORL (NCT07110857)
- Testing
- Cervical plexus block with 0.2 % Naropeine
- Where
- 7 sites in France
- Volunteers
- 346 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Pain Management, Penile Surgery-Related Pain
Anatomical Measurements of Pudendal Nerve Block in Children
This prospective observational study aims to investigate the relationship between anatomical parameters-specifically the distance from the anus to the needle insertion point and the depth required to reach the pudendal…
- Trial name
- NCT07348029
- Testing
- Neurostimulation-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain Management
Evaluation of Paro, a Therapeutic Assistance Robot in Analgesic Management During the Placement of a Peripheral Intravenous Line in Infants and Children.
Peripheral intravenous catheterization is one of the most frequently performed procedures in pediatric emergency departments and hospital units.
- Trial name
- PARO (NCT07299006)
- Testing
- Experimental group: Standard multimodal pain management strategy supplemented with the PARO therapeutic robot., Non-pharmacological and standard pharmacological interventions.
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- Fondation Lenval
Postoperative Care, Analgesia Assessment
Posthectomy in Pediatric Elective Surgery : a Comparison of Perioperative Analgesia Using Echo-guided Penile Block and Pudendal Block With neurostimuLation Technique
Context : Posthectomy is a surgical procedure that concerns around 30% of the male population, mainly in pediatrics. As this procedure is mainly performed on an outpatient basis, the implementation of an enhanced rehabilitation…
- Conditions
- Postoperative Care, Analgesia Assessment, Posthectomy, Postoperative Analgesia
- Trial name
- PinEAPPLE (NCT07191938)
- Testing
- Ultrasound guided penile block, Neurostimulation guided pudendal block
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Caen
Non-specific Low Back Pain (NSLBP)
Effects Of Sahrmann's Versus McGill Exercise In Patients With Non-Specific Low Back Pain
The goal of this clinical trial is to learn whether Sahrmann exercises or McGill exercises are more effective for reducing pain and improving function in adults with non-specific low back pain.
- Trial name
- NCT07659327
- Testing
- Sahrmann's Exercises, McGill Exercises
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Pain Management, Patient Satisfaction
Pain Management for In-Office Gynecologic Procedures Using a Risk-Stratification Pain Calculator
The goal of this clinical trial is to learn how using a risk-stratification calculator to determine the risk of a patient experiencing severe pain during an in-office gynecologic procedure and subsequently assigning pain…
- Conditions
- Pain Management, Patient Satisfaction, Gynecologic Procedures
- Trial name
- NCT07311824
- Testing
- Pain Calculator
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Carle Foundation Hospital
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy and Safety of Local Infiltration of RF16001 for Injection for Analgesia After Total Hip Arthroplasty in China
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial was conducted to investigate the efficacy and safety of RF16001 local infiltration for analgesia after total hip arthroplasty.
- Trial name
- NCT07872826
- Testing
- RF16001 for injection, Ropivacaine hydrochloride injection, 0.9% sodium chloride injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Postoperative Pain, Nerve Block
Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy
This study aims to evaluate and compare the analgesic efficacy of two ultrasound-guided regional anesthesia techniques, the serratus anterior plane (SAP) block and the serratus posterior superior intercostal plane (SPSIP) block…
- Conditions
- Postoperative Pain, Nerve Block, Mastectomy, Patient Outcome Assessment
- Trial name
- NCT07510269
- Testing
- SAP Block, SPSIP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Uludag University
Pain After Photorefractive Keratectomy, VAS Will be Used to Assess Pain Postoperative
Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study
The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.
- Trial name
- NCT06752486
- Testing
- Giving post photorefractive keratectomy for pain relief
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Sedation, Analgesia Assessment
A Prospective Multicenter Registry Study of Sedation and Analgesia in Critically Ill Patients
Sedation and analgesia are essential components of comprehensive care for intensive care unit (ICU) patients, particularly those receiving invasive mechanical ventilation, undergoing invasive procedures, or experiencing pain…
- Conditions
- Sedation, Analgesia Assessment, ICU
- Trial name
- NCT07885930
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Chao Yang Hospital