Clinical trials: Analgesia, Obstetrical
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Analgesia, Obstetrical
Tenoxicam for Intrapartum Analgesia
The aim of this study is to assess whether tenoxicam is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02549118
- Testing
- Tenoxicam, Pethidine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Epidural Analgesia, Hospital Follow-up
Obstetrical Analgesia in the Estaing Hospital Maternity. A Prospective Database to Study the Determinants of Labor Pain and the Resulting Maternal Non Satisfaction.
There is a trend to offer personalized care in many medical domains. In the field of labor pain, it appears that maternal satisfaction about care is multifactorial, and that labor pain is only one of its determinants, competing…
- Trial name
- AOMHE (NCT03314571)
- Testing
- analgesia for labor
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Clermont-Ferrand
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pain, Obstetric
Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration
We propose a prospective, randomized, single blinded trial with subjects recruited from the WRNMMC Labor and Delivery Unit to study post-partum efficacy of Exparel® for pain control in patients undergoing a vaginal delivery who…
- Trial name
- NCT03152877
- Testing
- Bupivacaine Liposome Injectable Product, 0.25% plain bupivacaine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Labor Pain
The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia
The purpose of this study is to see if an educational intervention provided to pregnant women in early labor has an effect on their decision to use epidural anesthesia for relief of labor pain.
- Trial name
- NCT02672397
- Testing
- Additional Epidural Education
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Analgesia, Obstetrical
Paracetamol for Intrapartum Analgesia
The aim of this study is to assess whether paracetamol is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02578251
- Testing
- Paracetamol, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Labor Pain
Spinal Sufentanil for Obstetric Analgesia
Background: This descriptive study was designed to evaluate effects and adverse effects of spinal sufentanil for relief of labor pain in primi- and multiparous women.
- Trial name
- NCT04141527
- Testing
- Spinal analgesia
- Volunteers
- 164 people
- Sponsor
- Lund University
Labor Pain, Analgesia, Obstetrical
Individualized Timing of Analgesia and Effectiveness of Labor Analgesia
Neuraxial analgesia is the gold standard to relieve labor pain. A recent "Practice guidelines for obstetric anesthesia" suggests that neuraxial analgesia should be provided in the early stage of labor (cervical dilation < 5 cm)…
- Conditions
- Labor Pain, Analgesia, Obstetrical, Early Medical Intervention
- Trial name
- NCT02920489
- Testing
- Individualized epidural analgesia, Routine epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Pelvic Pain
Impact of Thermotherapy During Childbirth on Postpartum Perineal Pain (PERISAFE)
Perineal pain is common after vaginal birth. Thermotherapy might be effective to limit postpartum perineal pain, thanks to the effects of local heating or cooling application.
- Trial name
- PERISAFE (NCT04778631)
- Testing
- Heat therapy, Cryotherapy
- Where
- 2 sites in France
- Volunteers
- 115 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Feeding, Analgesia Obstetrical
Intravenous Dexmedetomidine for Cesarean Section
Nervous, anxiety, fear and other psychological reactions always appears in parturients during cesarean section. This study intends to investigate the effectiveness and safety of dexmedetomidine combined with butorphanol tartrate…
- Conditions
- Breast Feeding, Analgesia Obstetrical, Postoperative Pain
- Trial name
- NCT03065530
- Testing
- Normal Saline, Dexmedetomidine 0.03ug/kg/h, Dexmedetomidine 0.05ug/kg/h
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Analgesia, Obstetrical
SKIN WHEAL - Subcutaneous or Intradermal Lidocaine in Epidural for Laboring Pain.
The purpose of this study is to explore the differences between the pain associated with epidural Tuohy needle insertion with prior administration of subcutaneous or intradermal lidocaine using two different pain assessment tools…
- Trial name
- NCT06236126
- Testing
- 1% Lidocaine Injection
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Labor Epidural Analgesia, Perfusion Index
Perfusion Index Variability During Epidural Labor Analgesia
This prospective, single-centre observational study evaluates changes in the peripheral Perfusion Index (PI) - a non-invasive parameter derived from the pulse-oximetry photoplethysmographic waveform - in women receiving epidural…
- Conditions
- Labor Epidural Analgesia, Perfusion Index, Pain
- Trial name
- NCT07831967
- Testing
- Epidural (or opioid-only combined spinal-epidural) labor analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Labor Pain, Nociceptive Pain
Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia.
Pain has been defined by the International Association for the Study of Pain (IASP) as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage".
- Conditions
- Labor Pain, Nociceptive Pain, Epidural Analgesia, NOL Index
- Trial name
- NCT05898737
- Testing
- NOL-Index
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Analgesia, Obstetrical
Hyoscine ButylBromide for Intrapartum Analgesia
The aim of this study is to assess whether hyoscine butylbromide is as effective as pethidine for analgesia during the first stage of labor.
- Trial name
- NCT02557087
- Testing
- Hyoscine, Pethidine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Analgesia, Obstetrical, Obstetric Surgical Procedures
Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery
Intrathecal (IT) opioids are commonly administered with local anesthetic during spinal anesthesia for post-Cesarean delivery analgesia. Traditionally, IT morphine has been used but the use of IT hydromorphone is growing.
- Trial name
- NCT02789410
- Testing
- Morphine, Hydromorphone
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Mayo Clinic
Labor Pain, Pregnancy
The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
The objective of this study will be to compare epidural infusion management, specifically looking at infusion rate changes, in patients who receive forceps deliveries versus normal spontaneous vaginal deliveries.
- Trial name
- NCT00443560
- Testing
- Case controlled analysis of epidural labor analgesia patterns
- Where
- United States
- Volunteers
- 2,162 people, healthy volunteers welcome
- Sponsor
- Northwestern University