Clinical trials: Analgesia, Epidural
Post Operative Pain
Comparison of Ultrasound-Guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia
There are limited studies comparing these two modalities ( thoracic epidural and erector spine block) for relieving the pain after thoracic surgeries .this study aim to investigate this purpose
- Trial name
- TEAVSESPB (NCT06571188)
- Testing
- THORACIC EPIDURAL BLOCK, ERECTOER SPINE BLOCK
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Menoufia University
Pregnant Women>37SA
EpiConCES - Epidural Lidocaine for Conversion to CaEsarean Section
The need to resort to a midwifery course work in cesarean is a common practice. Epidural analgesia for labor analgesia is practiced in 90% of women in obstetric work, as when the cesarean decision is taken course work in practice…
- Trial name
- EpiConCES (NCT02895022)
- Testing
- Lidocaine 2% adrénalinée, Epidural catheter, Caesarean section
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Labor Pain
Assessment of Catheter Flow Direction Using Color Flow Doppler in Labor Epidurals
Epidural analgesia is commonly used for pain relief in labor and involves placement of a catheter in the epidural space. Failure of epidural analgesia may occur in 12-16% of epidural catheter placements.
- Trial name
- NCT05126745
- Testing
- color flow Doppler ultrasonography
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pectus Excavatum
Prospective Trial: Pain Management After Pectus Excavatum Repair, Epidural Versus PCA
Pectus excavatum, the most common chest wall deformity, occurs in roughly one in 1000 children. Operative repair of the anterior thoracic concavity has transitioned to the minimally invasive approach with substernal bar placement…
- Trial name
- PectusEpiPCA (NCT01863498)
- Testing
- Epidural, PCA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Mercy Hospital Kansas City
Labor Pain, Breakthrough Pain
Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During Labour
A novel epidural delivery regimen was developed: Variable volume automated mandatory bolus (AMB) (VVAMB) will advance individualisation of labour epidural analgesia, by which a larger volume of bolus may contribute to better…
- Trial name
- VVAMB (NCT04011150)
- Testing
- Epidural infusion pump, Ropivacaine, Fentanyl
- Where
- Singapore
- Volunteers
- 197 people
- Sponsor
- KK Women's and Children's Hospital
Labor Analgesia
Do Epidurals Placed at a Lower Level Improve Labor Analgesia?
The investigators wish to compare the analgesia provided by epidurals placed high in the lumbar spine versus epidurals place low in the lumbar spine.
- Trial name
- NCT00954317
- Testing
- epidural placed low, high epidural
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Victoria Hospital, Canada
Analgesia, Epidural
Effect of Continuous Thoracic Epidural Analgesia on Gut Motility Following Emergency Laparotomy
Continuous thoracic epidural analgesia plays a very vital role in patients undergoing exploratory laparotomy. It not only supports a stable perioperative hemodynamics but also helps in early return of bowel activity.
- Trial name
- NCT03145389
- Testing
- Epidural catheter placement
- Volunteers
- 60 people
- Sponsor
- Banaras Hindu University
Caesarean Delivery
Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or Methadone
More and more women are on buprenorphine or methadone during pregnancy for a history of opioid addiction. Currently, pain control after cesarean section for women already on these medications, if they need operative delivery, is…
- Trial name
- NCT02091297
- Testing
- TAP Block, Ropivacaine, Acetaminophen
- Where
- 3 sites in United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pain Insensitivity, Congenital
Comparison of Levobupivacaine, Ropivacaine and Bupivacaine in Epidural Anaesthesia
This study compares the clinical efficacy of newer local anaesthetic drugs Levobupivacaine and Ropivacaine with Bupivacaine in lumbar epidural anaesthesia for hip surgeries.
- Trial name
- NCT02513433
- Testing
- Bupivacaine, Levobupivacaine, Ropivacaine
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Colon Cancer, Rectal Cancer
Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery
This is a prospective randomized study of 114 patients. The purpose of this study is to compare the efficacy of two standard methods of analgesia for pain control in patients undergoing elective colon and rectal surgery, as…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- NCT01552226
- Testing
- Continuous Preperitoneal Analgesia, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Trinity Health Michigan
Labor Epidural Analgesia, Perfusion Index
Perfusion Index Variability During Epidural Labor Analgesia
This prospective, single-centre observational study evaluates changes in the peripheral Perfusion Index (PI) - a non-invasive parameter derived from the pulse-oximetry photoplethysmographic waveform - in women receiving epidural…
- Conditions
- Labor Epidural Analgesia, Perfusion Index, Pain
- Trial name
- NCT07831967
- Testing
- Epidural (or opioid-only combined spinal-epidural) labor analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Labour Analgesia, Epidural Anaesthesia
Higher vs Lower Lumber Epidural Catheter Insertion During Labour: A Randomised Trial to Compare Efficacy.
This study will randomise pregnant women to labour epidural at a higher versus a lower lumbar level. Outcomes relating to success or failure of the epidural catheter at this level will be assessed.
- Trial name
- NCT06850636
- Testing
- Epidural Analgesia
- Where
- Ireland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Low Back Pain, Inflammatory Response
The Effect of Resolvins on the Resolve of Inflammatory Low Back Pain
Brief Summary: Inflammatory back pain is a chronic condition localized in the axial spine and sacroiliac joints.1 It often accompanies mechanical issues like lumbar disc herniation.
- Conditions
- Low Back Pain, Inflammatory Response, Lumbar Disc Herniation
- Trial name
- NCT06356844
- Testing
- Resolvin supplement
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Epidural Analgesia, Obstetric
Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery
To evaluate the levels of morphine in a patient's blood when morphine is given into the epidural space in the form of DepoDur® either alone or following a dose of lidocaine also given in the epidural space.
- Trial name
- NCT00804609
- Testing
- DepoDur following epidural lidocaine, DepoDur following spinal anesthetic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Thoracotomy, Sternotomy
Does Thoracic Epidural Analgesia Influence Urinary Micturition by Patients Undergoing Thoracic Surgery?
Under the influence of epidural analgesia, patients may not feel the urge to urinate, which can result in urinary retention and bladder overdistension.
- Trial name
- NCT00976313
- Testing
- Assessment of urinary micturition after thoracotomy, International Prostate Symptom Score
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Labor
Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?
Labor patients who meet inclusion and exclusion criteria will be consented to be participate in this study to determine if the use of a peanut shaped birthing ball reduces the length of labor and reduces the incidence of cesarean…
- Trial name
- NCT02539563
- Testing
- peanut shaped birthing ball
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Postoperative, Regional Anesthesia
Registry for Acute Pain Treatment
The German Network for acute pain management and Regional Anesthesia (NRA) is a multi-center, non-interventional registry and benchmark project, assessing and analysing clinical and patient-reported procedural and outcome data of…
- Trial name
- NCT02846610
- Where
- Germany
- Volunteers
- 224,744 people
- Sponsor
- University Hospital, Saarland
Anesthesia, Epidural, Hypotension
Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
The purpose of this pilot trial is to examine the feasibility and ease of use of monitoring by ClearSight in laboring and delivering patients with the intent to compare time-to-treatment of hypotension between conventionally…
- Trial name
- NCT05906368
- Testing
- ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Radicular Pain, Adhesiolysis
Determinants of Clinical Outcome After Caudal Epidural Adhesiolysis for Chronic Lumbar Radicular Pain
Chronic lumbar radicular pain is a frequently encountered condition that can cause marked pain, limited physical function, and a substantial decline in quality of life.
- Conditions
- Radicular Pain, Adhesiolysis, Disc Disease Lumbar
- Trial name
- NCT07487935
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mersin University