Clinical trials: Analgesia, Epidural
Pregnant Women
Interest of the Injection of Morphine, in Addition to a Local Anesthetic When Performing a Combined Spinal-epidural for Labor Analgesia
The addition of morphine to a local anesthetic when performing an epidural analgesia during labor analgesia has improved the efficiency and the action duration of analgesia.
- Trial name
- MASEA (NCT02868944)
- Testing
- experimental group : sequential combined spinal epidural with local anesthetic injection (chirocaine) associated with morphine (sufentanil)., control group : sequential combined spinal epidural with local anesthetic injection (chirocaine) alone.
- Where
- France
- Volunteers
- 144 people
- Sponsor
- CHU de Reims
Assess Women Awareness and Fear About EDA for Labor
"Awareness, Preconception, and Fear of Epidural Analgesia Among Childbearing Women in Saudi Arabia."
The aim of our study is to measure the level of awareness, preconceptions, and level of fear regarding epidural analgesia among childbearing women in KKUH in Riyadh.
- Trial name
- NCT05596604
- Testing
- survey- no intervention
- Where
- Saudi Arabia
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- King Khalid University Hospital
Labor, Analgesia, Epidural
Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia
Epidural chloroprocaine is often used in obstetrical anesthesia because of its fast onset and short duration. These properties make it an ideal drug to use for epidural anesthesia in patients undergoing postpartum tubal ligation.
- Trial name
- NCT00487084
- Testing
- Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy Related, Analgesia, Epidural
Dural Puncture Epidural vs Standard Epidural Analgesia in Labor
This randomized prospective study compares Dural Puncture Epidural (DPE) and Standard Epidural Analgesia in term laboring women.
- Conditions
- Pregnancy Related, Analgesia, Epidural, Labor Pain
- Trial name
- DPE-LABOR (NCT07278895)
- Testing
- Dural Puncture Epidural (DPE), Standard Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Pain Syndrome, Dizziness
Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery
Prevention of postoperative pain is essential for the recovery of esophageal surgery. Epidural analgesia is a traditional and standard perioperative pain management for these patients.
- Conditions
- Pain Syndrome, Dizziness, Vomiting, Itching
- Trial name
- NCT06704698
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Zhejiang Cancer Hospital
Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural
Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
The investigators hypothesize that US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy resulting in…
- Trial name
- NCT06397300
- Testing
- bilateral Ultrasound guided erector spinae plane (ESP) block, quadratus lumborum block, lumbar epidural
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia
Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and…
- Conditions
- Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia, Analgesia, Lidocaine Adverse Reaction
- Trial name
- LARA (NCT05368753)
- Testing
- Blood sample, Lidocain, ropivacaine
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cancer Pain, Opioid Use
Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment
In 2012, more than 14 million cases of cancer were diagnosed worldwide, with the forecast for 2025 exceeding 20 million. Pain is the most critical symptom that accompanies cancer.
- Conditions
- Cancer Pain, Opioid Use, Cost Analysis, Palliative Care
- Trial name
- NCT05558397
- Testing
- Interventional Group (Epidural morphine), Control Group (Oral morphine)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Alfenas
Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H)
Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Introduction: Major abdominal surgery encompasses a broad range of surgical procedures in heterogeneous patient populations.Management of postoperative pain has received keen attention in recent years with considerable concurrent…
- Conditions
- Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H), Colectomy Left/Right/Total Under Laparotomy, Hepatectomy
- Trial name
- NCT07901582
- Testing
- Epidural administered opioid
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens
Pregnancy Related
Epidural Versus Low-dose Spinal for Analgesia of Late First Stage of Labor
The aim of this study is to compare the effect of epidural analgesia versus low-dose spinal analgesia in parturient in the late first stage of labor regarding time needed to perform the block, duration of the intra- and…
- Trial name
- NCT05056142
- Testing
- Epidural Anesthesia, Spinal Analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Labor Pain
Characteristics of the Tsui Test and Pressure Waveform to Confirm Epidural Catheter Placement in Parturients With BMI ≥50 kg/m2
The prevalence of obesity has increased worldwide, and the anesthetic care of patients with obesity remains a challenge for providers despite advances.
- Trial name
- NCT05361512
- Testing
- Tsui test, epidural waveform analysis
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Acute Post-thoracotomy Pain
Efficacy of Patient Controlled Epidural Anesthesia Versus Continuous Epidural Analgesia for Post-thoracotomy Pain
Postoperative thoracotomy pain is normally managed with an epidural catheter and continuous epidural analgesia (CEA). However, for some surgical procedures, patient controlled epidural anesthesia (PCEA) is more effective but…
- Trial name
- NCT01560429
- Testing
- Patient controlled epidural analgesia, Continuous epidural analgesia
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Queen's University
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Virtual Reality, Anesthesia
HoloLens: an Objective Alternative to the Operator's Memory
Neuraxial anesthesia has traditionally been a 'blind' technique relying on users' feel and skill, both are subjective, lack complete accuracy and influenced by patient's physique variations that are quite challenging, and lead to…
- Conditions
- Virtual Reality, Anesthesia, Epidural
- Trial name
- Hololens (NCT04028284)
- Testing
- HoloLens-guided epidural, US-guided epidural
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pain
Patient Controlled Epidural Analgesia Versus Continuous Epidural Infusion: Obstetrical and Neonatal Outcomes
The investigators intend to perform a large randomized trial using standardized obstetrical and anesthetic practice at a single institution to determine the effects of patient controlled epidural analgesia on obstetrical and…
- Trial name
- Epidural (NCT00810914)
- Testing
- bupivicaine epidural, bupivicaine epidural infusion patient epidural, bupivicaine
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Epidural, Analgesia
Epidural Analgesia and Delivery of Second Twin
Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed.
- Conditions
- Epidural, Analgesia, Labor Pain
- Trial name
- Epidural (NCT04608006)
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Abdelrady S Ibrahim, MD
Pregnant Women, Labor Pain
Neuraxial Labor Analgesia and Offspring Neurodevelopment
How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring…
- Conditions
- Pregnant Women, Labor Pain, Analgesia, Epidural, Infants
- Trial name
- NCT04964206
- Testing
- Neuraxial labor analgesia, No neuraxial labor analgesia
- Where
- 2 sites in China
- Volunteers
- 4,645 people
- Sponsor
- Dong-Xin Wang
Analgesia, Thoracic Tumors
Real-time Ultrasound Guidance for Thoracic Epidural Blocks
Various modalities have been proposed for real-time confirmation of loss of resistance (LOR) for thoracic epidural blocks. With real-time ultrasound (US) guidance, the anesthesiologist attempts to visualize the sonographic…
- Conditions
- Analgesia, Thoracic Tumors, Abdomen Tumors, Rib Fractures
- Trial name
- NCT05165498
- Testing
- Real-time ultrasound guidance for thoracic epidural catheter placement.
- Where
- Chile
- Sponsor
- University of Chile
Pregnancy
Aseptic Techniques During Epidural Analgesia in the Labor Floor
There is an increasing trend in the incidence of infection related to epidural anesthesia. This could be related to methods of aseptic technique as adopted by the anesthesiologist during the performance of the procedure.
- Trial name
- EAS (NCT01235858)
- Testing
- wearing of sterile gowns, No gown
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain, Thoracotomy
Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy
Objective: Epidural analgesia is the gold standard for post-thoracotomy pain relief but is contraindicated in certain patients. An alternative is continuous wound catheter analgesia.
- Trial name
- NCT01698203
- Testing
- ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun), ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Strasbourg, France