Clinical trials: Anal Function Preservation
Diverting Ileostomy, Middle and Low Rectal Cancer
Diverting Ileostomy and Anal Functional Outcomes After Anus Preservation Surgery
Analyze the occurrence of complications, rectal function and quality of life after anus-preserving surgery for middle and low rectal cancer, so as to evaluate the role of protective ileostomy.
- Conditions
- Diverting Ileostomy, Middle and Low Rectal Cancer, Functional Outcome, Stoma Complications
- Trial name
- NCT04776421
- Testing
- Diverting ileostomy
- Volunteers
- 300 people
- Sponsor
- The First Hospital of Jilin University
Rectal Neoplasms
Trial of Robotic Versus Laparoscopic-assisted Radical Resection for Rectal Cancer
This study compared robot-assisted total mesorectal excision (RTME) and laparoscopic total mesorectal excision (LTME) with regard to urinary function, sexual function and sphincter- preservation outcomes for low rectal cancer.
- Trial name
- TRVL (NCT02673177)
- Testing
- robot-assisted total mesorectal excision, laparoscopic total mesorectal excision
- Volunteers
- 225 people
- Sponsor
- Southwest Hospital, China
Locally Advanced Rectal Cancer (LARC), Immunotherapy
Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study
The study is a multicenter, randomized controlled, phase III clinical study, and the purpose of the study is to explore the complete response rate (CR, Defined as pathological complete response (pCR) + Clinical complete response…
- Conditions
- Locally Advanced Rectal Cancer (LARC), Immunotherapy, Radiotherapy, Total Neoadjuvant Therapy
- Trial name
- NCT07020247
- Testing
- Anti-PD-1 antibody drug named Serplulimab, Radiotherapy, Chemotherapy
- Where
- China
- Volunteers
- 184 people
- Sponsor
- West China Hospital
Rectum Cancer
Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer
In this clinical trial, the investigators compared anal function, genitourinary function, quality of life, perioperative safety, and oncological prognosis after CSPO for patients with low rectal cancer, using ISR as a control, to…
- Trial name
- NCT06567756
- Testing
- CSPO, ISR
- Volunteers
- 84 people
- Sponsor
- Changhai Hospital