Clinical trials: Anakinra
Kawasaki Disease, Anakinra
Non Inferiority KawasakI Trial With Anakinra
This is a multicenter, open-label, randomized, controlled, interventional trial followed by a long-term observational extension period in patients with Kawasaki Disease (KD) to be treated eitherwith endovenous Immunoglobulins…
- Trial name
- NIKITA (NCT06697431)
- Testing
- Anakinra, Intravenous Immunoglobulins, Human
- Sponsor
- Meyer Children's Hospital IRCCS
Dengue, Dengue With Warning Signs
Anakinra in Dengue With Hyperinflammation ( AnaDen )
This study aims to evaluate the effect of anakinra in dengue patients with hyperinflammation as compared to placebo Primary Objective: To evaluate the efficacy of Anakinra in moderate-severe dengue patients with…
- Conditions
- Dengue, Dengue With Warning Signs, Severe Dengue, Anakinra
- Trial name
- NCT05611710
- Testing
- Anakinra
- Where
- Vietnam
- Volunteers
- 160 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Sepsis, Neuroinflammatory Response
Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia
The goal of this clinical trial is to investigate the immunomodulatory effects of the drugs dexamethasone, tocilizumab and anakinra in healthy male subjects aged 18 to 35 undergoing experimental endotoxemia.
- Conditions
- Sepsis, Neuroinflammatory Response, Immunosuppresion, Endotoxemia
- Trial name
- DEDICATE-LPS (NCT06624436)
- Testing
- Dexamethasone, Tocilizumab, Anakinra
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
COVID-19, Cytomegalovirus (CMV), Tocilizumab, Anakinra, Mortality
The Relationship Between CMV* Reactivation and Anti-cytokine Treatment in Critical COVID-19 Patients
The risk of secondary infection is high in critical patients hospitalized with the diagnosis of COVID-19. Immunosuppressive treatments are commonly used in critical COVID-19 patients, and immune dysfunction and CMV reactivation…
- Trial name
- Cytomegalovir (NCT05419206)
- Testing
- CMV DNA analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 167 people
- Sponsor
- Ramazan Gozukucuk
Endometriosis, Anakinra
Pilot Study of the IL-1 Antagonist Anakinra for the Treatment of Endometriosis Related Symptoms
All current FDA approved medications to treat endometriosis pain including danazol, GnRH agonists (Lupron, Zoladex and Synarel), GnRH antagonist (elagolix) and depo-provera prevent or contradict pregnancy.
- Conditions
- Endometriosis, Anakinra, Markers of Inflammation
- Trial name
- NCT03991520
- Testing
- Anakinra 100Mg/0.67Ml Inj Syringe
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
COVID-19 Infection, ANAKINRA Treatment
Anakinra for COVID-19 Respiratory Symptoms
The main objective of the ANACONDA-COVID-19 trial is to assess the efficacy of Anakinra + optimized Standard of Care (oSOC) as compared to oSOC alone on the condition of patients with COVID-19 infection and worsening respiratory…
- Conditions
- COVID-19 Infection, ANAKINRA Treatment, Optimized Standard of Care (oSOC)
- Trial name
- ANACONDA (NCT04364009)
- Testing
- Anakinra plus oSOC, oSOC
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Tours
Anakinra, Kineret
A Pilot Study Using Anakinra/Kineret for the Treatment of Patients With Severe Atopic Dermatitis
Background: Severe atopic dermatitis, also known as eczema, is a chronic inflammatory skin condition that affects both children and adults and causes severe itching and skin redness.
- Conditions
- Anakinra, Kineret, Atopic Dermatitis, Eczema
- Trial name
- NCT01122914
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)