Clinical trials: Anaesthesia Induction
Induction of Anaesthesia, Muscle Relaxants
Developing a Physiology-Pharmacodynamic Model of Rocuronium Dose and Cardiac Output to Investigate the Onset Time of Neuromuscular Relaxation
After a patient is put to sleep, a breathing tube is often placed through the larynx (voice box) into the trachea (windpipe). To place a breathing tube requires the muscles of the jaw, voice box, and diaphragm to be relaxed.
- Conditions
- Induction of Anaesthesia, Muscle Relaxants, Rocuronium
- Trial name
- NCT07168252
- Testing
- Rocuronium dosing
- Volunteers
- 32 people
- Sponsor
- Clare Hayes-Bradley
Patients Undergoing Anaesthesia Induction
Hemodynamic Effects of Anesthesia Induction
The idea of that project is to characterize the hemodynamic changes of a daily used clinical intervention (induction of anesthesia) in a highly controlled environment by two hemodynamic monitoring devices.
- Trial name
- KEM-HEN (NCT06421181)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Kliniken Essen-Mitte
Preoxygenation, Anaesthesia Induction
An Algorithmic Approach to Preoxygenation
The aim of this randomized controlled trial is to evaluate an algorithmic approach to gradually adding pressure-supported ventilation and end-tidal positive pressure when conventional tidal volume breathing is insufficient for…
- Conditions
- Preoxygenation, Anaesthesia Induction, Non-invasive Positive Pressure Ventilation
- Trial name
- NCT06736197
- Testing
- Group TVB, Group PSV, Group PSV+PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 378 people
- Sponsor
- Pamukkale University
Induction of Anaesthesia
Explore the Clinical Application Value of Ciprofol in Painless Colonoscopy
This study used propofol as a positive control, and adopted a large-sample, multi-center, randomized, double-blind, positive parallel controlled trial design to explore the clinical application value of ciprofol in painless…
- Trial name
- NCT05294679
- Testing
- Propofol, Ciprofol
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Anaesthesia Induction
Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial
Intravenous anaesthesia induction is nowadays considered as gold standard, mainly because of the possibility of the rapid therapeutic intervention while having secured i.v. line.
- Trial name
- Induration (NCT04527757)
- Testing
- Inhalation induction, Intravenous induction
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Brno University Hospital
Induction of General Anaesthesia
A Phase IIa Study Investigating the Tolerance, Efficacy and Safety of HSK3486
This is a Phase IIa, open-label, propofol-controlled ,dose-escalation, multi-center Study to evaluate the tolerance, efficacy and safety of HSK3486 for induction of general anesthesia in elective surgery patients.This study is…
- Trial name
- NCT03698617
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Induction of Anaesthesia
A Phase IV Study Investigating the Effects of Remifentanil Concentrations on Propofol Requirements for Loss of Consciousness, Response to Painful Stimuli, Bispectral Index and Associated Haemodynamic Changes
A prospective, randomised, phase IV trial including 150 patients. To evaluate the effects of varied concentrations of remifentanil on the proposal requirements for the loss of consciousness and response to pain and to evaluate…
- Trial name
- NCT02287181
- Testing
- Remifentanil, Propofol, Bispectral index
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Induction of Anaesthesia
Comparison of Etomidate, Propofol and Etomidate-propofol Combination in Terms of Effects on Haemodynamic Response to Intubation
The purpose of this study is to evaluate the effect of propofol, etomidate and propofol-etomidate combination on hemodynamic responses during laryngoscopy and tracheal intubation and assess the adverse effect related to this…
- Trial name
- NCT02186990
- Testing
- propofol, etomidate, etomidate-propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ordu University
Induction of Anaesthesia, Age
Onset Time of Thiopental Versus Propofol in the Elderly
This study is aimed at increasing the safety of the use of anaesthesia in an elderly population (> 60 years). Patients with decreased physiological reserve, including all elderly patients, have an increased risk of getting an…
- Trial name
- NCT00965107
- Testing
- Thiopental, Propofol
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
General Anaesthesia, Induction of Anaesthesia
Efficacy and Safety Study of Two Propofol Formulations
The purpose of the study to compare Propofol-MCT/LCT with LCT in terms of their efficacy and safety during total intravenous anaesthesia
- Trial name
- NCT00506246
- Testing
- Propofol
- Where
- 3 sites in China
- Volunteers
- 220 people
- Sponsor
- B. Braun Melsungen AG