Clinical trials: Amputation, Limb Loss
People With Trans-femoral Amputation
Effects of Microprocessor-controlled Knee Joints on Community Outcomes
About 21% to 35% of people with limb loss are those who lost their limb at trans-femoral level (i.e. above the knee). The increasing number of diabetes-related limb loss (amputation) and the rising proportion of older adult…
- Trial name
- NCT04112901
- Testing
- Microprocessor-controlled knee joints, Non-microprocessor-controlled knee joints
- Volunteers
- 330 people
- Sponsor
- University of Derby
Amputation
Comparison of Prosthetic Feet for the Geriatric Patients(CPF)
The purpose of this study is to determine whether the geriatric prosthetic foot 1M10 is superior to the classical SACH (Solid Ankle Cushion Heel) foot, when used by indoor ambulators with a transtibial amputation.
- Trial name
- CPF (NCT03249883)
- Testing
- SACH prosthetic foot, 1M10 prosthetic foot
- Volunteers
- 14 people
- Sponsor
- Loewenstein Hospital
Amputation, Prosthesis User
Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators
The goal of this study is to find out if using microprocessor-controlled prosthetic knees (MPKs), prosthetic knees with a built-in computer, improves health outcomes related to falls in adults who use above-knee prostheses.
- Conditions
- Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower
- Trial name
- NCT06937242
- Testing
- Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hanger Institute for Clinical Research and Education, LLC
Amputation, Transtibial Amputation - Unilateral
The Relationship of Quadriceps and Hamstring Strength on Timed up and go Scores in Transtibial Amputees
To investigate the correlation between the effect of quadriceps and hamstring strength on timed up and go scores in adults with tarns - tibial amputation
- Conditions
- Amputation, Transtibial Amputation - Unilateral, Quadriceps Muscle Strength, Hamstring Muscle Strength
- Trial name
- NCT07067203
- Testing
- Lafayette hand held dynamometer, Timed up and Go test
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Amputation
Clinical Investigation (Beta) of a New Developed Prosthetic Knee
The aim of this investigation is to evaluate the efficacy of the investigational device regarding performance improvements and satisfaction in descending activities for moderate to high active prosthesis users within the intended…
- Trial name
- NCT06748729
- Testing
- Navii Knee
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Össur Iceland ehf
Lower Limb Amputation
Outcome Measures for Lower Limb Amputees - A Repeatability Study
During any period of rehabilitation it is important to select meaningful tests that; measure what you want, are responsive to changes in the patient's condition and, easy to use in the clinical settings.
- Trial name
- NCT01953939
- Testing
- Prosthetic Limb Users
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Queen Margaret University
Amputation, Traumatic Amputation of Lower Extremity
Sitting Balance in Lower Limb Amputees
The aim of this study is to compare the sitting and standing postural stability of transfemoral individuals with healthy individuals with similar demographic characteristics.
- Trial name
- NCT05597696
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lower Limb Amputation Below Knee (Injury)
Auto Control of Volume Management for Limb Loss
The aim of this research is to create a prosthetic system that will automatically adjust the fit of the socket and create a well-fitting prosthesis for people with leg amputations who experience volume fluctuations when using…
- Trial name
- NCT03550118
- Testing
- Adjustable socket
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Washington
Lower Limb Amputation, Prosthesis Users
Dual-Task Balance Training in Traumatic Lower-Limb Prosthesis Users
This randomized controlled trial will evaluate the effectiveness of dual-task balance training on balance, mobility, and mental health among traumatic lower-limb prosthesis users in the Gaza Strip.
- Conditions
- Lower Limb Amputation, Prosthesis Users, Balance Impairment, Mobility Limitations
- Trial name
- DTBT-LLA (NCT07706452)
- Testing
- Dual-Task Balance Training, Standard Rehabilitation
- Where
- Palestinian Territories
- Volunteers
- 63 people
- Sponsor
- Al-Azhar University - Gaza
Rehabilitation
Motor Imagery Practice on Amputees (MIPA)
Motor imagery practice (MIP), which is the repeated internal representation of a movement without engaging its physical execution and which shares a neurofunctional equivalence with physical practice, has been show to contribute…
- Trial name
- MIPA (NCT03125538)
- Testing
- Motor Imagery, Control Task
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Laboratoire Interuniversitaire de Biologie de la Motricité
Upper Limb Amputation Below Elbow
Evaluation of a Multi-electrode Prosthesis Control System for Real-world Tasks Performance in Individuals With Upper Limb Transradial Amputation
This study tests how well the Phantom X prosthesis control system works. The system helps control a prosthetic hand using muscle signals from the arm. You'll wear a non-invasive version for one day in the clinic.
- Trial name
- EMPOWER (NCT07071584)
- Testing
- Cutaneous Prosthesis Control System
- Where
- 2 sites in United States
- Sponsor
- Phantom Neuro Inc.
Amputation
Improving Outcomes Following Limb Loss: PALS Plus
Limb loss can result from a variety of etiologies including diabetes, trauma and cancer. Following limb loss, individuals are at elevated risk for activity limitations and participation restrictions with significant impact on…
- Trial name
- PALS-PLUS (NCT00447655)
- Testing
- Self-management and peer support
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Lower Limb Amputation
Muscle Strength Training in Lower Limb Amputee Patients
This study is a clinical trial that evaluates the best treatment option using a strength training protocol and an endurance training protocol in patients with lower limb amputations who use prostheses.
- Trial name
- NCT07261852
- Testing
- Muscle strengh training, Resistence training
- Volunteers
- 18 people
- Sponsor
- University of Gran Rosario
Lower Limb Amputation
Evaluation of a Novel Transfemoral Prosthetic Socket System
The purpose of the study is to evaluate residual limb circulation and skin health associated with the use of a novel prosthetic transfemoral socket system.
- Trial name
- NCT01846845
- Testing
- Conventional Prosthetic Transfemoral Socket System, Novel Prosthetic transfemoral socket system
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Ohio Willow Wood
Amputation, Amputation, Traumatic
Neuromusculoskeletal Interface for Bionic Arms
The overall objective of this proposal is to perform a first-in-human home trial of the Electronic Osseoanchored Prostheses for the Rehabilitation of Amputees (e-OPRA) implant system in individuals with transhumeral amputations…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Surgical, Upper Limb Amputation Above Elbow (Injury)
- Trial name
- NCT07032753
- Testing
- eOPRA, OPRA, eOPRA with sensory feedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Amputee, Plantar Pressure Distrubution
Comparison of Different Amputation Levels
Lower limb amputation is a factor that changes the individual's weight transfer, gait pattern, and trunk balance. This change plantar pressure distribution of both side and cause a series of problems to be exposed over time…
- Conditions
- Amputee, Plantar Pressure Distrubution, Balance
- Trial name
- NCT04330274
- Testing
- Bipedal with open eyes, Bipedal with closed eyes, Bipedal with open eyes and with platform
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Marmara University
Amputation, Rehabilitation
The Knowledge Gaps of Amputee Rehabilitation Course Content in Physiotherapy Curriculum
Understanding the knowledge gaps of amputee rehabilitation course content is essential for addressing these gaps. Identifying the course contents according to International Classification of Functioning, Disability and Health…
- Conditions
- Amputation, Rehabilitation, ICF
- Trial name
- NCT06569979
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Amputation, Amputation, Traumatic
Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control
The goal of this clinical trial is to systematically evaluate whether or not two commonly held fundamental assumptions for pattern recognition control translates to functional performance when tested on individuals aged 18 years…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User
- Trial name
- NCT07011420
- Testing
- Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Liberating Technologies, Inc.
Lower Limb Amputation Below Knee (Injury)
R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment
Lower limb amputees (LLA) rely on their prosthetic legs to remain active and lead an independent life. For most LLAs, a well-fitted prosthetic socket is the only option to interface with their prosthetic leg, however, it is a…
- Trial name
- ENABLE (NCT05425810)
- Testing
- Apply ENABLE sensing pad, Insert small pads at pressure tolerant locations
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- North Carolina State University