Clinical trials: Amoxicillin-clavulanate
Urinary Tract Infections
Oral vs Initial Intravenous Antibiotic Treatment of Urinary Tract Infections in Children: a RCT
The main objectives of the study are 1. to compare the efficacy of oral vs initial iv antibiotic treatment in children with a first episode of UTI 2.
- Trial name
- NCT00161330
- Testing
- oral amoxicilline/clavulanic acid, iv ceftriaxone
- Volunteers
- 440 people
- Sponsor
- University of Padova
Skin Diseases, Bacterial
Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections
The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ampicillin-sulbactam, and amoxicillin-clavulanate in the treatment of a complicated skin and/or skin structure…
- Trial name
- NCT00368537
- Testing
- Tigecycline, ampicillin-sulbactam
- Where
- 57 sites in United States, Canada and 10 more
- Volunteers
- 550 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Fever, Pneumonia
The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines
Fever can develop after fiberoptic bronchoscopy (FB) in about 2.5 - 16 % of adult patients. We evaluated the impact of oral amoxicillin/clavulanate (AC) on incidence of postbronchoscopic fever and pneumonia.
- Trial name
- NCT01089218
- Testing
- oral amoxicillin/clavulanate 1g (875/125mg), control
- Volunteers
- 241 people
- Sponsor
- Seoul National University Hospital
COVID-19 Pneumonia
Azithromycin+Amoxicillin/Clavulanate vs Amoxicillin/Clavulanate in COVID19 Patients With Pneumonia in Non-intensive Unit
The global pandemic of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Wuhan, China, in December 2019, and has since spread worldwide.1 As of April 14…
- Trial name
- AziA (NCT04363060)
- Testing
- Azithromycin with amoxicillin/clavulanate, amoxicillin/clavulanate
- Where
- 3 sites in France
- Volunteers
- 104 people
- Sponsor
- Nantes University Hospital
Antibiotic Side Effect
Evaluation of Bifidobacterium Breve PRL2020 in Preventing Antibiotic-Associated Side Effects From Amoxicillin or Amoxicillin/Clavulanic Acid
This study aims to evaluate the efficacy and safety of the probiotic Bifidobacterium breve PRL2020 in preventing gastrointestinal and extra-intestinal side effects caused by Amoxicillin or Amoxicillin/Clavulanic Acid in pediatric…
- Trial name
- NCT06850714
- Testing
- Bifidobacterium breve PRL2020 (Brevicillin®), Amoxicillin or Amoxicillin/Clavulanic Acid
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Pharmacokinetics, Amoxicillin-clavulanate
Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)
Pharmacokinetics of antibiotics in critically ill neonates, infants and children on extracorporeal membrane oxygenation (ECMO).
- Conditions
- Pharmacokinetics, Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem
- Trial name
- PADECMO (NCT06426836)
- Testing
- Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem
- Where
- 3 sites in Belgium
- Volunteers
- 300 people
- Sponsor
- University Hospital, Ghent
Tuberculosis, Pulmonary
Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB
The overall goal of this exploratory proof-of-concept study is to determine whether, in participants with pulmonary tuberculosis caused by M.
- Trial name
- NCT03174184
- Testing
- Rifampin, MEROPENEM 2 grams TID, MEROPENEM 1 gram TID
- Where
- South Africa
- Volunteers
- 112 people
- Sponsor
- Johns Hopkins University
Sinusitis, Bacterial Infections
Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis
This is a clinical study organized to collect clinical data to better define the activity of some antimicrobials already marketed in Italy and in the rest of the world for the treatment of acute bacterial rhinosinusitis
- Trial name
- NCT00493038
- Testing
- Moxifloxacin (Avelox, BAY12-8039), Amoxicillin/Clavulanate
- Where
- 34 sites in Italy
- Volunteers
- 293 people
- Sponsor
- Bayer
Mandible Fracture, Post-operative Antibiotics
The MANTRA Trial (MANdibular TRauma and Antibiotic Use)
1. FULL TITLE OF THE PROJECT Should we use post-operative antibiotics following surgery for patients with mandible fractures? The MANTRA trial (MANdibular TRauma and Antibiotic use) 2.
- Trial name
- MANTRA (NCT05964140)
- Testing
- Different post-operative antibiotic regimens following surgical treatment of mandible fractures
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,841 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Severe Community-acquired Pneumonia
Amoxicillin/Clavulanic Acid Susceptibility in Acute Community-acquired Pneumonia Requiring Intensive Care Management
Severe community-acquired pneumonia (CAP) and community-acquired aspiration pneumonia (CAAP) are common reasons for adult emergency department visits and subsequent admission to the intensive care unit (ICU).
- Trial name
- CAP-ICU (NCT07322549)
- Testing
- Susceptibility to AMC, Susceptibilty to 3GC
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Helicobacter Pylori Infection
Efficacy of Seven-day Combined Rabeprazole Plus Levofloxacin Plus Augmentin for Eradication of Helicobacter Pylori
This prospective controlled randomized open-label clinical trial is designed to determine the eradication rate of 7-day levofloxacin, amoxicillin/clavulanate and rabeprazole regimen compared with 7-day standard triple therapy for…
- Trial name
- NCT01575899
- Testing
- Levofloxacin-Amox/clav., Clarithromycin-Amoxicillin
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Sinusitis
Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate
The aim is to determine if high-dose amoxicillin/clavulanate is more effective than standard-dose amoxicillin/clavulanate in treating acute bacterial sinusitis in adults seen at a primary care office.
- Trial name
- NCT02340000
- Testing
- standard dose amoxicillin/clavulanate, high dose amoxicillin/clavulanate
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Albany Medical College