Clinical trials: Amoxicillin-clavulanate
Otitis Media
Levofloxacin In The Treatment Of Children With Recurrent And/or Persistent Acute Otitis Media
The purpose of this study is to demonstrate non-inferiority of levofloxacin compared with amoxicillin/clavulanate on the clinical response at the end of therapy in infants and children who have recurrent and/or persistent acute…
- Trial name
- NCT00051753
- Testing
- levofloxacin; amoxicillin/clavulanate
- Volunteers
- 1,643 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Sinusitis, Bacterial Infections
Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis
This is a clinical study organized to collect clinical data to better define the activity of some antimicrobials already marketed in Italy and in the rest of the world for the treatment of acute bacterial rhinosinusitis
- Trial name
- NCT00493038
- Testing
- Moxifloxacin (Avelox, BAY12-8039), Amoxicillin/Clavulanate
- Where
- 34 sites in Italy
- Volunteers
- 293 people
- Sponsor
- Bayer
HIV Infections, Sinusitis
Acupuncture and Herbal Treatment of Chronic HIV Sinusitis
To compare Traditional Chinese Medicine versus standard antibiotic therapy consisting of pseudoephedrine ( Sudafed ) plus amoxicillin / clavulanate potassium combination ( Augmentin ) in reducing symptoms and recurrence of acute…
- Trial name
- NCT00002149
- Testing
- Clavulanate potassium, Pseudoephedrine hydrochloride, Amoxicillin trihydrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Immune Enhancement Project
Tuberculosis, Pulmonary
The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis
The goal of this randomized controlled trial is to study the early bactericidal activity in adult patients with smear-positive pulmonary tuberculosis.
- Trial name
- BLAST (NCT05664568)
- Testing
- Cephalexin, Amoxicillin-Clavulanate 500 Mg-125 Mg Oral Tablet, Standard of care treatment of tuberculosis
- Where
- 3 sites in Australia
- Volunteers
- 30 people
- Sponsor
- Western Sydney Local Health District
Sinusitis
Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate
The aim is to determine if high-dose amoxicillin/clavulanate is more effective than standard-dose amoxicillin/clavulanate in treating acute bacterial sinusitis in adults seen at a primary care office.
- Trial name
- NCT02340000
- Testing
- standard dose amoxicillin/clavulanate, high dose amoxicillin/clavulanate
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Antibiotics Causing Adverse Effects in Therapeutic Use
Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure
Among patients receiving dental implants, does the choice of antibiotics reduce the frequency of early implant failure ?
- Trial name
- NCT04980170
- Testing
- Clindamycin 300 mg, Amoxicillin with Clavulanic Acid 635mg
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- Jordan University Hospital
Diarrhoea
A Study to Evaluate the Effect and Safety of Idoform Plus on Bowel Side Effects in Healthy Subjects Treated With Amoxicillin/ Clavulanate
It is hypothesized that Idoform plus will recuce the occurence of gastrointestinal side effects related to the use of antibiotics
- Trial name
- NCT01491659
- Testing
- Idoform Plus
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Rhinosinusitis
Levofloxacin in Bacterial Rhinosinussitis
Inflammatory paranasal diseases are among the most common diseases in ENT In Russia, puncture method has been conventional approach to treatment of maxillary sinusitis.
- Trial name
- Levolet (NCT02712502)
- Testing
- Levofloxacin, Amoxicillin-Potassium Clavulanate Combination
- Volunteers
- 100 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Sinusitis, Acute
Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis
Acute Bacterial Rhinosinusitis (ABRS) is a respiratory inflammation commonly seen in clinical practice, which has with respiratory symptoms including nasal congestion, rhinorrhoea, postnasal discharge and cough and is associated…
- Trial name
- NCT01934231
- Testing
- Amoxicillin-Potassium Clavulanate Combination
- Where
- 3 sites in Japan
- Volunteers
- 27 people
- Sponsor
- GlaxoSmithKline
Fever, Pneumonia
The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines
Fever can develop after fiberoptic bronchoscopy (FB) in about 2.5 - 16 % of adult patients. We evaluated the impact of oral amoxicillin/clavulanate (AC) on incidence of postbronchoscopic fever and pneumonia.
- Trial name
- NCT01089218
- Testing
- oral amoxicillin/clavulanate 1g (875/125mg), control
- Volunteers
- 241 people
- Sponsor
- Seoul National University Hospital
Infectious Disease
Effects of Phenoximethylpenicillin, Amoxicillin and Amoxicillin-clavulanic Acid on the Gut Microbiota
The overall aim of the project is to fill an important knowledge gap on the ecological effects of selected antibiotics. The results will be used to guide treatment decisions for common infections to as much as possible reduce the…
- Trial name
- EPAAC (NCT04084106)
- Testing
- Phenoxymethylpenicillin, Amoxicillin, Amoxicillin-clavulanic acid
- Where
- Sweden
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Acute Otitis Media
Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children
This is a randomized, controlled trial studying the effects of various antimicrobial treatments on the intestinal microbiome of small children.
- Trial name
- AOMMi (NCT02935374)
- Testing
- Amoxicillin, Amoxicillin-Potassium Clavulanate, Macrolide
- Where
- Finland
- Volunteers
- 73 people
- Sponsor
- University of Oulu
Tonsillitis Streptococcal
Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin
To compare intravenous Co-amoxiclav versus Benzyl penicillin in children with severe streptococcal tonsillitis in terms of efficacy, safety and cost effectiveness.
- Trial name
- NCT04215770
- Testing
- inj co-amoxiclav 50 units/kg/day vs inj Benzyl Penicillin 25000 units/kg/day
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- Combined Military Hospital, Pakistan
Otitis Maedia
Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media)
This post-marketing surveillance study of CLAVAMOX® was designed to collect and assess the information on proper use, such as safety and efficacy, under actual use conditions, targeting pediatric Japanese patients with diseases…
- Trial name
- NCT01406275
- Testing
- Amoxicillin and clavulanate
- Volunteers
- 363 people
- Sponsor
- GlaxoSmithKline
Helicobacter Pylori Infection
Efficacy of Seven-day Combined Rabeprazole Plus Levofloxacin Plus Augmentin for Eradication of Helicobacter Pylori
This prospective controlled randomized open-label clinical trial is designed to determine the eradication rate of 7-day levofloxacin, amoxicillin/clavulanate and rabeprazole regimen compared with 7-day standard triple therapy for…
- Trial name
- NCT01575899
- Testing
- Levofloxacin-Amox/clav., Clarithromycin-Amoxicillin
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Bioequivalence
Bioequivalence Study of Clavamox, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (Pharmtechnology LLC, Belarus), and Augmentin®, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions
This is an open-label, randomized, single-center, single-dose, two-treatment, two-sequence, two-period, crossover, comparative study, where each subject will be randomly assigned to the reference or the test formulation in each…
- Trial name
- NCT03616301
- Testing
- Clavamox, Augmentin®
- Where
- Russia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Pharmtechnology LLC
Adenotonsillar Hypertrophy,Under 12 Years.
Intravenous Enhancin[Co-amoxiclav] Versus Postoperative Enhancin in Prevention of Postadenotonsillectomy Morbidity.
Null hypothesis; The efficacy of Enhancin]Co-Amoxiclav given as a single intravenous dose at induction is not better than a five days oral course of the same given postoperatively in reducing postoperative morbidity after…
- Trial name
- NCT01267942
- Testing
- Enhancin
- Where
- Kenya
- Volunteers
- 126 people
- Sponsor
- University of Nairobi
Drug-Induced Liver Injury
Risk of Acute Liver Injury in Users of Antimicrobials
Moxifloxacin is a broad-spectrum antibacterial agent used to treat common community-acquired respiratory tract infections, complicated intra-abdominal infections, and pelvic inflammatory disease.
- Trial name
- NCT01434173
- Testing
- Moxifloxacin (Avelox, BAY12-8039), Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
- Where
- United States
- Volunteers
- 1,299,056 people
- Sponsor
- Bayer
Severe Community-acquired Pneumonia
Amoxicillin/Clavulanic Acid Susceptibility in Acute Community-acquired Pneumonia Requiring Intensive Care Management
Severe community-acquired pneumonia (CAP) and community-acquired aspiration pneumonia (CAAP) are common reasons for adult emergency department visits and subsequent admission to the intensive care unit (ICU).
- Trial name
- CAP-ICU (NCT07322549)
- Testing
- Susceptibility to AMC, Susceptibilty to 3GC
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Pneumonia, Bacterial
A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization
The purpose of this study is to test if intravenous sulopenem and an oral drug, PF-03709270 are safe and effective in patients that are hospitalized with community acquired pneumonia.
- Trial name
- NCT00797108
- Testing
- sulopenem and PF-03709270, Ceftriaxone and amoxicillin/clavulanate
- Where
- 24 sites in United States, Australia and 3 more
- Volunteers
- 35 people
- Sponsor
- Pfizer