Clinical trials: Amenorrhea
Breast Cancer, Perimenopause
AMH Dynamic Changes to Predict Ovarian Reserve in Perimenopausal Breast Cancer
This study is a prospective observational cohort study aimed at developing a clinical model based on dynamic changes in anti-Müllerian hormone (AMH) to predict ovarian reserve in perimenopausal women with hormone…
- Conditions
- Breast Cancer, Perimenopause, Ovarian Reserve
- Trial name
- NCT07497191
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Secondary Amenorrhea
A Phase 3, Randomized, Three-Cycle, Double-Blind, Placebo-Controlled Study to Evaluate Induction of Secretory Conversion of Endometrium and Withdrawal Bleeding for Secondary Amenorrhea
This study will be a Phase 3, randomized, three-cycle, double-blind, placebo-controlled, parallel group, multiple-dose design. The study design has four phases: Screening Period; Open-Label Estrogen-Priming Period (Run-In…
- Trial name
- SPRY (NCT02019589)
- Testing
- Progesterone
- Where
- 22 sites in United States
- Volunteers
- 6 people
- Sponsor
- TherapeuticsMD
Breast Cancer Nos Premenopausal
Neoadjuvant Chemotherapy for Operable Premenopausal Breast Cancer Patients
The current study is a multicentre, randomized, open (unblended), prospective clinical trial which is sponsored by the researchers.
- Trial name
- NCT01503905
- Testing
- Docetaxel, epirubicin, cyclophosphamide
- Where
- 17 sites in China
- Volunteers
- 600 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Infant, Extremely Premature
Description of Practices Implemented in the Birth of Living Children Before 24 Weeks of Amenorrhea
Every year, at the Nice University Hospital, about sixty deliveries take place before 24 weeks of amenorrhea. The child is not viable because of his extreme immaturity.
- Trial name
- NCT03403894
- Testing
- Asking caregivers in their practice
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hypothalamic Amenorrhea
Total Antioxidant Capacity Before and After HRT in Hypotalamic Amenorrhea
The aim of our study is to investigate the effects of 6 months oh HRT on total anti-oxidant capacity, clinical, endocrine and metabolic features in women affected by hypotalamic amenorrhea.
- Trial name
- NCT02984696
- Testing
- 1 mg of transdermal estradiol daily and 10mg of oral MPA
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Catholic University of the Sacred Heart
Premature Between 32 and 36 Weeks of Amenorrhoea
Place of Birth and Neonatal Health in Cases of Premature Birth Between 32 and 36 Weeks of Amenorrhoea
Moderate and late premature babies (32-36 weeks of amenorrhoea) account for around 6% of births, but 20% of neonatal deaths. These children also have an increased risk of neonatal morbidity and long-term neurodevelopmental…
- Trial name
- PREM3236 (NCT06078618)
- Where
- France
- Volunteers
- 240,000 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to
The Health of Competitive Fitness Athletes
Fitness athletes emphasize the value of staying lean, muscular and defined, and motivates and inspires followers through social media.
- Conditions
- Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to, Body Image, Perfectionism
- Trial name
- NCT03007459
- Testing
- Psychological health, Physiological health
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Mental Health Wellness 1, Depression, Anxiety
Mental Health in Fitness Instructors
The aim of this project is to improve the evidence-base regarding lifestyle and mental health symptoms among fitness instructors.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety, Eating Disorders, Eating Behavior
- Trial name
- NCT04135729
- Where
- Norway
- Volunteers
- 304 people
- Sponsor
- Norwegian School of Sport Sciences
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois Chicago
Menstruation Disturbances, Luteal Phase Defect
Bioenergetics of Exercise-Induced Menstrual Disturbances
Menstrual disturbances are frequently observed in physically active women and female athletes. Short term prospective studies have shown that diet and exercise interventions can lead to decreases in Luteinizing hormone (LH)…
- Conditions
- Menstruation Disturbances, Luteal Phase Defect, Amenorrhea, Oligomenorrhea
- Trial name
- BioE (NCT04938622)
- Testing
- Sedentary Control, Exercising control, 15 percent energy deficit
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Penn State University
Preterm Labour
Monocyte Chemotactic Protein-1 (MCP-1) Expressing Monocytes to Predict Preterm Delivery: PhenoMAP Study
The threat of preterm labour (PTL) is the first cause of hospitalization in the course of pregnancy. Its diagnostic is based on clinical examination with a positive predictive value of about 40 %.
- Trial name
- PHENOMAP (NCT01340222)
- Testing
- biological samples
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Amenorrhea
Effect of Intense Training on Ovarian Function and Bone Turnover
The investigators propose a prospective, longitudinal, department funded study protocol to evaluate whether changes in energy availability, during a period of highly intensified exercise training, will increase bone turnover…
- Trial name
- NCT02224976
- Testing
- Intensified Training
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Amenorrhea, Hypogonadotropic Hypogonadism
Baselines in Reproductive Disorders
The purpose of the study is to explore the way in which gonadotropins (pituitary hormones) are released into the body. The knowledge acquired in this study will be used for the diagnosis and treatment of reproductive endocrine…
- Conditions
- Amenorrhea, Hypogonadotropic Hypogonadism, Kallmann's Syndrome
- Trial name
- NCT00456274
- Testing
- Frequent baseline blood sampling
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Massachusetts General Hospital
Amenorrhea, Functional Hypothalamic Amenorrhea (FHA)
Effects of Resistance Training on Women With Functional Hypothalamic Amenorrhea
Functional hypothalamic amenorrhea (FHA) is a condition where women lose their menstrual periods, typically due to a combination of stress and insufficient calorie intake to fuel their daily physical activity (low energy…
- Conditions
- Amenorrhea, Functional Hypothalamic Amenorrhea (FHA), Low Energy Availability, Relative Energy Deficiency in Sport
- Trial name
- NCT07612735
- Testing
- Resistance Training Program
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Catholic University of Murcia
Pregnancy, Prematurity
Vaginal Probiotics During Pregnancy After Premature (24-32 Weeks of Gestation) Preterm Rupture of Membranes
The goal of this clinical trial is to evaluate the feasibility of the randomized controlled trial (RCT). Secondary objectives include comparing the microbiota of preterm babies born after premature rupture of membranes across…
- Conditions
- Pregnancy, Prematurity, PPROM
- Trial name
- PROB-PROM (NCT06965049)
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Polycystic Ovary Syndrome (PCOS)
Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women
The purpose of this research study is to collect specimen samples and study medical information from women with Polycystic Ovary Syndrome (PCOS) and women without PCOS.
- Trial name
- NCT01889199
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Female Athlete Triad
Effect of Acupuncture and Diet Modification on amenorrheaIN FEMALE ATHLETE TRIAD
The present study will be designed to investigate the effect of acupuncture and diet modification using soy products on amenorrhea in female athlete triad.
- Trial name
- NCT03817827
- Testing
- Acupuncture, Diet supplementary
- Where
- Egypt
- Sponsor
- National Research Centre, Egypt
Infertility, Ovulation Induction
SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Efficacy and safety studies in the past have suggested that a starting dose of 75 International Unit (IU) of SJ-0021, and an increase in the dose by 37.5 IU every 7 days, are safe for treatment of subjects with ovulatory…
- Trial name
- NCT01185782
- Testing
- Gonalef® (Follitropin alfa), Purified pituitary gonadotropin (Fertinorm-P®)
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Autoimmune Disease, Infertility
Steroid Therapy in Autoimmune Premature Ovarian Failure
No therapy for infertile patients with premature ovarian failure has been proven effective. Some anecdotal reports have suggested that high dose, long term prednisone (steroid) therapy may be useful in treating autoimmune ovarian…
- Conditions
- Autoimmune Disease, Infertility, Premature Ovarian Failure
- Trial name
- NCT00001306
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)