Clinical trials: Amblyopia
Amblyopia
Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old
This study will evaluate the effectiveness of refractive correction alone for the treatment of previously untreated strabismic or combined-mechanism amblyopia in children 3 to <7 years old with visual acuity of 20/40 to 20/400
- Trial name
- ATS13 (NCT00669539)
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia, Anisometropia
A Randomized Controlled Trial of Gabor-Based Perceptual Learning for Adult Amblyopia
This study is initiated and conducted by the Shanghai Eye Disease Prevention and Treatment Center / Shanghai Eye Hospital. Many people once believed that amblyopia (commonly known as "lazy eye") could only be treated during…
- Trial name
- NCT07764198
- Testing
- Gabor training
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jiannan Huang
Amblyopia, Strabismus
Determining the Efficacy of Full-time Occlusion Therapy in Severe Amblyopia at Different Ages
Objective: To find out how much visual improvement is possible in severe amblyopia using full-time occlusion therapy with an eye patch and to see if improvement is influenced by the patient's age.
- Trial name
- NCT02113709
- Testing
- Occlusion therapy by Eye Patch, Occlusion therapy
- Where
- Pakistan
- Volunteers
- 115 people
- Sponsor
- Mughal Eye Trust Hospital
Amblyopia
Trial Comparing Near Versus Distance Activities While Patching for Amblyopia in Children 3 to <7 Years Old
Ths purpose of this study is to determine whether "near" activities enhance the effect of patching on visual acuity improvement in strabismic and anisometropic amblyopia when compared with "distance" activities in the treatment…
- Trial name
- ATS6 (NCT00315198)
- Testing
- Eye Patch, Near activities, Distance activities
- Where
- 2 sites in United States
- Volunteers
- 425 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia
NEIVATECH Virtual Reality-based System for Amblyopia
The NEIVATECH system has been designed to provide binocular vision training to 7-15 year old amblyopic children by discriminating Gabor patches presented with different contrast to each eye as a perceptual learning task.
- Trial name
- NEIVATECH (NCT04819386)
- Testing
- Active vision therapy sessions with the NEIVATECH Virtual Reality-based system
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Increase-Tech
Amblyopia
Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds
The purpose of this study is: To compare the effectiveness of weekend atropine plus near activities and daily patching plus near activities for moderate amblyopia (20/40 to 20/100) and severe amblyopia (20/125 to 20/400) in…
- Trial name
- ATS9 (NCT00315328)
- Testing
- Atropine, Patching, Near activities
- Where
- 2 sites in United States
- Volunteers
- 233 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia
Trial Comparing Daily Atropine Versus Weekend Atropine
The goals of this study are: To compare the visual acuity outcome in the amblyopic eye after 17 weeks of daily use of atropine versus weekend-only use of atropine.
- Trial name
- NCT00094614
- Testing
- Atropine
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia
Caffeine in Amblyopia Study
Prospective data on the visual acuity response in children treated by patching concurrently treated with caffeine and estimate the magnitude of effect that might be seen in a randomized trial (if no improvement in acuity is seen…
- Trial name
- CAS (NCT02594358)
- Testing
- Caffeine
- Where
- United States
- Sponsor
- Johns Hopkins University
Amblyopia
Patch-free Occlusion Therapy
The purpose of the study is to determine whether a patch-free occlusion therapy leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is…
- Trial name
- NCT05440448
- Testing
- Patch-free occlusion therapy, Adhesive patch
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Retina Foundation of the Southwest
Refractive Errors, Esotropia
Changes in Refractive Error in Patients With Both Partially Refractive Esotropia and Amblyopia
To investigate changes in refractive errors and evaluate clinical outcomes of strabismus surgery in patients with both amblyopia and partially refractive esotropia (PAET).Amblyopic patients with PAET were enrolled.
- Conditions
- Refractive Errors, Esotropia, Amblyopia Strabismic
- Trial name
- NCT04429659
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Sakarya University
Amblyopia
Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old
The purpose of the study is: To compare the effectiveness and safety of weekend atropine augmented with a plano lens for the sound eye versus weekend atropine alone for moderate amblyopia (20/40 to 20/100) in children 3 to less…
- Trial name
- ATS8 (NCT00315302)
- Testing
- Atropine, Plano Lens
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Jaeb Center for Health Research
Visual Impairment, Amblyopia
Developing Better Computerised Vision Tests (CVTV)
Clinical vision measurements usually involve printed charts with an eye care professional interpreting patient responses to generate a score. Those scores determine the need for or outcome of treatment.
- Conditions
- Visual Impairment, Amblyopia, Macular Degeneration, Ophthalmic Disease
- Trial name
- CVTV (NCT06224751)
- Testing
- Near logMAR letter acuity, Near LogMAR word acuity, Red Green Stereoacuity
- Where
- United Kingdom
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust