Clinical trials: Alzheimer's
Sleep, Sleep Disorders
Z-Drugs for Sleep Disorders in Alzheimer's Disease
The purpose of this study is to determine whether Zolpidem and Zoplicone are efective in the treatment of sleep disorders in Alzheimer's disease (AD)
- Conditions
- Sleep, Sleep Disorders, Insomnia, Alzheimer's Disease
- Trial name
- NCT03075241
- Testing
- Zolpidem, Zoplicone
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Brasilia University Hospital
Alzheimer Disease
Effect of Indomethacin on the Progression of Alzheimer's Disease
The purpose of this study is determine whether indomethacin is able to retard disease progression in patients with mild to moderate Alzheimer's disease.
- Trial name
- NCT00432081
- Testing
- indomethacin
- Where
- 2 sites in Netherlands
- Volunteers
- 160 people
- Sponsor
- Radboud University Medical Center
Dementia, Alzheimer Disease (AD)
Impact of Musical Therapeutic Intervention on Depression in Dementia Patients and Caregiver Burden
This single-site interventional study evaluated the effects of receptive live music therapy on depression in patients with dementia and caregiver burden at the AMAVIDA Memory Care Unit in Fort Myers, Florida.
- Conditions
- Dementia, Alzheimer Disease (AD), Depression Chronic, Caregiver Burden of People With Dementia
- Trial name
- NCT07069530
- Testing
- Receptive Music Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Florida SouthWestern State College
Alzheimer's Dementia (AD), Family Caregivers
Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease
EYE-TAR(AD+) is an observational study based on the same design as the princeps EYE-TAR(MA) study, but with a larger number of patients and including an additional evaluation of Facial emotion recognition (based on a more…
- Trial name
- NCT05267028
- Testing
- AD-TAR, AD-Cognitive Stimulation
- Where
- Monaco
- Volunteers
- 16 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Education
Education of Caregivers of Alzheimer's Patients
Purpose of the Research: This study will be conducted to determine the effect of the education given to caregivers of Alzheimer's patients registered to home health services on their knowledge and attitudes towards Alzheimer's…
- Trial name
- NCT06182930
- Testing
- Within the scope of the research, caregivers will be given face-to-face training in 2 sessions, 15 days apart.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline
High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and…
- Trial name
- NCT07444554
- Testing
- High-Velocity Resistance Training
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Alzheimer's Disease
A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD).
This randomized, double-blind, placebo-controlled, parallel group study will evaluate the efficacy and safety of crenezumab versus placebo in participants with prodromal to mild AD.
- Trial name
- CREAD (NCT02670083)
- Testing
- Crenezumab
- Where
- 196 sites in United States, Australia and 28 more
- Volunteers
- 813 people
- Sponsor
- Hoffmann-La Roche
Alzheimer Disease, Early Onset
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease
This is a Phase 1b, multicenter, randomized, placebo-controlled, double-blind, multiple ascending dose (MAD) study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of DNL628 in participants…
- Trial name
- NCT07328451
- Testing
- DNL628
- Where
- 4 sites in Netherlands, United Kingdom
- Volunteers
- 68 people
- Sponsor
- Denali Therapeutics Inc.
Alzheimer's Disease
Drug Interaction Study Between AZD3480 and Warfarin
The purpose of the study is to evaluate if AZD3480 and warfarin interact with each other or not, i.e. show the same or altered plasma concentration profiles when co-administered compared to administered alone.
- Trial name
- DDI (NCT00689637)
- Testing
- AZD3480, Warfarin
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Alzheimer's Disease
Extension Study of Participants From SPG302-ALZ-101
This study will evaluate the long-term safety and efficacy of participants enrolled in SPG302-ALZ-101 with mild to moderate Alzheimer's Disease (AD)
- Trial name
- NCT06833281
- Testing
- SPG302
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Spinogenix
Alzheimer&Amp;Amp;#39;s Disease, Alzheimer Disease
Large-coil Parietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Alzheimer Disease (AD)
The goal of this clinical trial is to learn if using large-coil (or "deep") repetitive transcranial magnetic stimulation (rTMS) targeting the precuneus and surrounding areas is feasible, tolerable, and potentially efficacious for…
- Conditions
- Alzheimer&Amp;Amp;#39;s Disease, Alzheimer Disease, Dementia Alzheimer Type, Mild Alzheimer&Amp;Amp;#39;s Disease
- Trial name
- PROMIS-AD (NCT06597942)
- Testing
- TMS
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of California, Los Angeles
Alzheimer's Disease, Vascular Dementia
A Noval Tau Tracer in Young Onset Dementia
Dementia is a clinical syndrome which characterized by progressive cognitive impairment, behavior disturbance and dysfunction of daily activity.
- Conditions
- Alzheimer's Disease, Vascular Dementia, Dementia
- Trial name
- NCT04248270
- Testing
- 18F-PM-PBB3
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Subjective Cognitive Decline (SCD)
Personalized Brain Health Service and Dementia Prevention
This study evaluates the feasibility of implementing a Brain Health Service (BHS) to assess and reduce dementia risk in individuals with Subjective Cognitive Decline (SCD).
- Trial name
- B-HEALTH (NCT07698431)
- Testing
- Multimodal Lifestyle Intervention, Lifestyle Recommendations and Counseling
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Alzheimer Disease, Caregiver Stress Syndrome
Learning and Improving Alzheimer's Patient-Caregiver Relationships Via Smart Healthcare Technology
The purpose of this project is to develop a monitoring, modeling, and interactive recommendation solution (for caregivers) for in-home dementia patient care that focuses on caregiver-patient relationships.
- Trial name
- NCT04536701
- Testing
- Mood Monitoring and Behavioral Recommendation System
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Primary Care, Alzheimer Disease
Designing a Tailored Primary Care Intervention to Manage the Burden of Caring for Patients Living with Alzheimer's Disease (or a Related Dementia)
The design of the intervention is an ongoing process which will consist of two phases: a determination of the intervention using the Delphi-modified consensus method and an assessment of its acceptability, as described in the…
- Trial name
- ISAMA-PP (NCT06852326)
- Where
- 3 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Alzheimer Disease
4Hz Transcranial Alternating Current Stimulation for Patients With Mild Alzheimer's Disease
The goal of this study is to explore the efficacy and safety of 4Hz transcranial alternating current stimulation (tACS) in patients with mild Alzheimer's disease (AD).
- Trial name
- NCT04088643
- Testing
- transcranial alternating current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Alzheimer Disease, Dementia
Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands
The investigators established the Faroese Alzheimer's Cohort with the aim to unravel genetic and environmental factors that influence the risk and/or susceptibility of Alzheimers disease (AD).
- Trial name
- NCT03628404
- Where
- Faroe Islands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Faroese Hospital System
Alzheimer's Disease
Study of Magnetic Fields to Treat Alzheimer's Disease
To determine if low level magnetic fields can help to improve memory in patients diagnosed with Alzheimer's disease.
- Trial name
- NCT01313806
- Testing
- Resonator
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- pico-tesla Magnetic Therapies, LLC
Alzheimer's Disease, Dementia
Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies
The Alzheimer's Prevention Registry (www.endALZnow.org) will collect contact and demographic information on individuals. The objective is to provide information the latest news and advances in Alzheimer's prevention research, and…
- Trial name
- APR (NCT02022943)
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Banner Health
Alzheimer Disease, Lewy Body Disease
Immunohistochemical Study of Neurodegenerative Diseases
The subject uses cytof to analyze PBMC of sporadic AD and DLB, which is used to reveal the differences in immune characteristics of the two diseases at the single-cell level, build immune models for specific diseases, and define…
- Conditions
- Alzheimer Disease, Lewy Body Disease, Neurodegenerative Diseases
- Trial name
- NCT05518409
- Testing
- Detection of cytof in peripheral PBMC, Donepezil for patients with AD and DLB
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.