Clinical trials: Alveolar Bone Loss, active
Alveolar Ridge Resorption After Extraction, Alveolar Bone Loss
L-PRF Block vs Composite Graft for Horizontal Ridge Augmentation
Brief SummaryCopy and paste the text below into the Brief Summary text box:The purpose of this randomized controlled clinical trial is to evaluate and compare the clinical, radiographic, and histological outcomes of horizontal…
- Conditions
- Alveolar Ridge Resorption After Extraction, Alveolar Bone Loss, Jaw, Edentulous, Partially, Horizontal Ridge Defect
- Trial name
- NCT07918950
- Testing
- L-PRF Block with DBBM, Autogenous Bone / DBBM Composite Graft
- Where
- United Arab Emirates
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss, Alveolar Bone Regeneration Following Odontectomy
Effect of Ascorbic Acid-Loaded I-PRF With Partially Demineralized Dentin Graft on Alveolar Ridge Preservation
The goal of this clinical trial is to find out which treatment best preserves the jawbone after tooth extraction in adults planning to receive a dental implant later.
- Conditions
- Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss, Alveolar Bone Regeneration Following Odontectomy, Assisted Alveolar Bone Healing After Dental Extraction, Alveolar Bone Preservation
- Trial name
- AA-IPRF-PDDG (NCT07916545)
- Testing
- Alveolar Ridge Preservation Using Partially Demineralized Dentin Graft alone, Alveolar Ridge Preservation Using PDDG Combined with I-PRF, Alveolar Ridge Preservation Using PDDG Combined with Ascorbic Acid-Loaded I-PRF
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nahda University
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Alveolar Bone Loss, Sinus Floor Augmentation
Two Bovine Xenografts in Lateral Window Sinus Augmentation With or Without Bone Marrow Blood
The goal of this clinical trial is to learn whether adding a small amount of blood taken from the jawbone marrow improves new bone formation when two different bone graft materials are used in maxillary sinus lift surgery.
- Conditions
- Alveolar Bone Loss, Sinus Floor Augmentation, Edentulous Alveolar Ridge
- Trial name
- NCT07904065
- Testing
- Deproteinized Bovine Bone Mineral (Bio-Oss), Deproteinized Bovine Bone Mineral (InterOss), Mandibular Bone Marrow Blood Aspiration
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad del Desarrollo
Alveolar Bone Loss, Edentulism Nos
The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation
Pneumatization of the maxillary sinus may lead to insufficient bone volume for dental implant placement in the edentulous posterior maxilla.
- Trial name
- NCT06533397
- Testing
- Sinus floor elevation (SFE), preoperative cone beam computed tomography (CBCT), postoperative CBCT
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Semmelweis University
Tooth Loss, Dental Implant Failed
Investigation of the Effect of Horizontal Platelet Rich Fibrin Placed in Tooth Extraction Sockets on Bone Formation
Dental implants, the treatment of complete and partial edentulous cases involving the restoration of lost teeth, have become a registered and widely used treatment option.
- Conditions
- Tooth Loss, Dental Implant Failed, Alveolar Bone Loss
- Trial name
- NCT07011303
- Testing
- H-PRF, L-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dehiscence, Tooth Extraction
Effect of Collagen Membrane on Ridge Preservation
This study will evaluate whether adding a resorbable collagen membrane to an anorganic bone-collagen composite (ABCC) graft improves ridge preservation after tooth extraction.
- Conditions
- Dehiscence, Tooth Extraction, Alveolar Bone Loss
- Trial name
- NCT07580495
- Testing
- Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Debora Dias
Dental Implant, Immediate Dental Implant Placement
Melatonin Effect on Immediate Dental Implants in the Posterior Mandible
This pilot randomized controlled clinical trial aims to evaluate the feasibility, clinical safety, and preliminary radiographic osteogenic effects of applying topical 1% w/w melatonin gel during immediate implant placement in the…
- Conditions
- Dental Implant, Immediate Dental Implant Placement, Alveolar Bone Loss, Bone Density
- Trial name
- NCT07869030
- Testing
- 1% w/w Melatonin Gel, Standard Immediate Dental Implant Placement
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Future University in Egypt
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Maxillofacial Bone Defect, Alveolar Bone Loss
Bone Marrow Mononuclear Cells for the Repair of Severe Maxillofacial Bone Defects
This is a single-center, single-arm, open-label clinical study conducted at the Department of Stomatology, Nanjing Drum Tower Hospital.
- Trial name
- NCT07852806
- Testing
- Autologous bone marrow-derived mononuclear cells (BMMNCs), Bio-Oss bone graft material with collagen membrane
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Alveolar Bone Loss, Alveolar Ridge Deficiency
Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement.
- Trial name
- NCT07841158
- Testing
- Customized porous zirconia shell
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mohammed Mahmoud Abed
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Bone Loss, Osteoclastic, Bone Loss, Alveolar
Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting
This study aims to evaluate bone formation in grafts in terms of its quality (density), quantity (volume) and maturation obtained with the application of a tissue-engineered bone grafting compound containing concentrated…
- Conditions
- Bone Loss, Osteoclastic, Bone Loss, Alveolar, Alveolar Bone Loss, Alveolar Bone Atrophy
- Trial name
- NCT04998058
- Testing
- Maxillary sinus floor elevation grafting with synthetic bone substitute.
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Periodontitis, Intrabony Periodontal Defect
Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread.
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect
- Trial name
- NCT07146776
- Testing
- open flap debridement with I-prf and xenogeneic graft, open flap debridement with saline and xenogenic graft
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Periodontal Disease, Periodontal Bone Loss
Laser Assisted Open Flap Debridement
The study involves the surgical treatment of patients with Stage I to III of periodontitis. Following completion of Steps 1 and 2 of periodontal therapy according to the EFP guidelines for the treatment of periodontitis, sites…
- Trial name
- LaserOpen (NCT07807215)
- Testing
- Mechanical Open Flap debridement, Laser assisted open flap debridement
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University
Alveolar Bone Loss, Dental Implant Failed
Simultaneous Implant Placement With Vertical and Horizontal Bone Augmentation
The purpose of this study was to report the clinical and radiographical outcomes of using autogenous cortical bone plates combined with sticky allogenic bone graft for augmenting maxillary anterior atrophic combined horizontal…
- Trial name
- NCT06313229
- Testing
- implant placement 6 months after ridge augmentation, implant placement Simultaneously with ridge augmentation
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Alveolar Bone Loss
VST vs Modified Periosteal Inhibition Technique
Losing a tooth in the upper front of the mouth is common, and many people choose a dental implant to replace it. When a tooth is removed, the thin layer of bone in front of the socket - the buccal, or front, bone - often shrinks…
- Trial name
- VST (NCT07784764)
- Testing
- VST, Mucoperiosteal inhibition
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tanta University
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University