Clinical trials: Alteration in Cognition
Burnout, Risk Reduction
Effectiveness of Online Therapy to Prevent Burnout
This study aims to address the reliability and validity of the Empowerment for Participation (EFP) batch of assessments to measure Burnout risk in relation to the efficacy of online interventions to provide proactive…
- Conditions
- Burnout, Risk Reduction, Cognitive Change
- Trial name
- NCT05343208
- Testing
- EFP Psychometric assessment to determine level of afflication
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- SciensCollege
Cognitive Change
Tulsi Consumption and Its Effects on Cognition, Stress and Anxiety
Tulsi and its effects on facilitative cognitive enhancement through lowering levels of stress and anxiety. A randomised placebo-controlled clinical trial.
- Trial name
- NCT03184909
- Testing
- Ocimum Sanctum
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Composite Interceptive Med Science
Cognitive Change
EMRESERVA to Enhance Cognitive Reserve in Multiple Sclerosis
Multiple Sclerosis(MS) is an immunological degenerative disease that affects central nervous system causing cognitive impairment, which is one of the most disabling symptoms in MS.
- Trial name
- NCT05546424
- Testing
- EMRESERVA
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cognitive Change, Metabolic Syndrome, Protection Against
Nutritional Intervention for Sustaining Health (NURISH) Trial
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Metabolic Syndrome, Protection Against, Diet, Healthy
- Trial name
- NCT06437860
- Testing
- MIND Diet, Control Diet
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cognitive Decline, Cognitive Change
Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia.
- Conditions
- Cognitive Decline, Cognitive Change, Cognitive Impairment, Postoperative Delirium
- Trial name
- NCT03839784
- Testing
- Neurocognition Interventions
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Cognitive Change
Mindfulness Training for Senior Leaders
The overarching goal of the project is to investigate if a mindfulness-based attention training (MBAT) program contextualized for Military Senior Leaders (SLs) might benefit SLs in three key domains: (1) cognitive abilities, (2)…
- Trial name
- NCT04576832
- Testing
- Mindfulness-Based Attention Training (MBAT) web-course
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Miami
PARKINSON DISEASE (Disorder)
Whole-Body Photobiomodulation for Motor and Cognitive Changes in Parkinson's Disease
This study aims to exploratorily evaluate the extent of motor and cognitive changes, as well as the safety, resulting from approximately 10 weeks of whole-body photobiomodulation (PBM) therapy (about three sessions per week, once…
- Trial name
- PBM (NCT07271927)
- Testing
- Photobiomodulation
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Pusan National University Yangsan Hospital
Cognitive Change, Growth; Stunting, Nutritional
The Sugira Muryango Longitudinal & Spillover Study
The Early Childhood version of Sugira Muryango is a family-based, home-visiting intervention targeted at early childhood development and implemented with families living in extreme poverty in three districts of Rwanda.
- Conditions
- Cognitive Change, Growth; Stunting, Nutritional, Language, Depression
- Trial name
- NCT05405400
- Where
- 3 sites in Rwanda
- Volunteers
- 2,932 people, healthy volunteers welcome
- Sponsor
- Boston College
Behavioral
Cognitive Changes in Childs After Anesthesia / Surgery
The role of surgical stress and anesthesia is unknown in the early childhood. In vitro and animal studies showed a risk for treatment with anesthesia in the developmental brain.
- Trial name
- NCT02658526
- Testing
- anesthesia - surgery
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Konstanze Plaschke
Cognitive Change
Dopamine Dorsolateral Prefrontal Cortex Behavioural Flexibility
Behavioural or cognitive flexibility (BF) is an essential ability which allows an organism to adaptively change responses in accordance with feedback of results.
- Trial name
- NCT03068884
- Testing
- Cathodal Transcranial direct current stimulation, L-Tyrosine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Aging
Neural Correlates of Successful Cognitive Aging
Normal aging is associated with gradual cognitive declines. These mild neurocognitive disturbances affect daily functioning, health status, and quality of life, and likely account for the roughly $2.9 billion lost by the elderly…
- Trial name
- NCT02628548
- Testing
- Cognitive training program
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Late Life Depression
One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term
The purpose of this study was to investigate the one-year trajectory of cognitive change in elderly patients with depression, to explore the transfer characteristics and transfer rules of various states of cognitive impairment in…
- Trial name
- NCT06447428
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Mental Processes, Cognitive Change
The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States
This is a randomized, double-blind, placebo-controlled, 4-week intervention clinical study assessing the efficacy of Mirtoselect®, Virtiva® Plus, and Enovita® on cognitive performance and mood states, and the occurrence of…
- Conditions
- Mental Processes, Cognitive Change, Mood Change
- Trial name
- NCT06309914
- Testing
- Enovita Grape Seed Extract, Mirtoselect Bilberry Extract, Virtiva Plus Ginko Biloba Extract
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Cognitive Change
Study of Low-intensity Focused Ultrasound Effects on Cognitive fMRI Signals
Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations.
- Trial name
- NCT05303428
- Testing
- Neuromodulation with low-intensity focused ultrasound
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Cognitive Change, Memory; Disturbance, Mild
The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology
This is a single-centre, single-blind, two-arms, controlled study to assess the efficacy and safety of food for special dietary use enriched with 5-hydroxytryptophan, L-theanine and Gamma-aminobutyric acid in generally healthy…
- Conditions
- Cognitive Change, Memory; Disturbance, Mild, Emotional Regulation, Concentration Ability Impaired
- Trial name
- Spread Bogatyr (NCT05543811)
- Testing
- Food for special dietary use
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Presymptomatic Disease, Mild Cognitive Impairment
Digitally-enhanced, Decentralized, Multi-omics Observational Cohort
The study is carried out as part of the GR2021 Priority project "Healthy Brains for life (Age 20-99): Digitally-enhanced personalized medicine study ANANEOS" and code numbered GR-00546 and it will look at the decentralized and…
- Conditions
- Presymptomatic Disease, Mild Cognitive Impairment, Memory Loss (Excluding Dementia), Cognitive Change
- Trial name
- ANANEOS (NCT04701177)
- Testing
- Teleph0s digital phenotyping platform
- Where
- 4 sites in Greece, Spain
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Greece 2021 Committee
Cognitive Change
Impact of Challenging Engagement on Cognition in Older Adults
The study will enroll 90 participants in the "Impact of Challenging Engagement" study and assign them to one of three groups: high-demand photography, moderate-demand photography, and active placebo.
- Trial name
- engAGE (NCT03962439)
- Testing
- High-Demand Photography, Moderate-Demand Photography, At-Home Engagement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Long COVID, Brain Fog
Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
The goal of this clinical trial is to test whether the intervention of probiotics supplement can improve symptoms of long covid syndrome. Participants will be given probiotics or placebo capsules for two month.
- Conditions
- Long COVID, Brain Fog, Cognitive Change
- Trial name
- COVID-19 (NCT06348212)
- Testing
- Lactobacillus paracasei PS23, microcrystalline cellulose
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Cognitive Change
PatiEnt Neuropsychological outcomeS After laseR Ablation
PatiEnt Neuropsychological outcomeS After laseR ablation
- Trial name
- PENSAR (NCT05075850)
- Testing
- Neuroblate System
- Where
- 7 sites in United States
- Volunteers
- 81 people
- Sponsor
- Monteris Medical
Breast Cancer
Rehabilitation of Cognitive Changes in Breast Cancer Survivors
The purpose of this study is to test a memory training program for breast cancer survivors who have problems with memory after receiving chemotherapy.
- Trial name
- NCT01182506
- Testing
- Cogmed Working Memory Training Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center