Clinical trials: Allergy Drug
Stevens-Johnson Syndrome, Kidney Failure, Chronic
HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction
Allopurinol-induced severe cutaneous adverse reaction (SCAR) is a rare but fatal condition. Previous reports have reported that HLA-B*5801 is an important genetic risk factor significantly associated with the development of…
- Trial name
- NCT03046914
- Testing
- HLA-B*5801 test
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Seoul National University Hospital
Drug Hypersensitivity
Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)
The objective of this study was to rule out a greater than 10% incidence of hypersensitivity to Vitrase following a single intradermal injection of 3 USP units Vitrase.
- Trial name
- NCT00198458
- Testing
- Vitrase
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Allergic Rhinitis
Traditional Chinese Medicine for the Treatment of Perennial Allergic Rhinitis on Gut Microbiota and Immune-modulation
40 allergic rhinitis patients in the acute phase will be enrolled in the study. All the allergic patients should be confirmed those who are over 20 years old and hypersensitive to house dust mite allergens confirmed by MAST test…
- Trial name
- NCT04388358
- Testing
- Shin-yi-san + Xiao-qing-long-tang + Xiang-sha-liu-jun-zi-tang by the weight of 9g+3g+3g/day
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Chang Gung Memorial Hospital
Post Operative Pain
Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.
This study was conducted to evaluate the efficacy of desensitizing agent Propolis, after an in -office vital tooth bleaching and to compare its desensitizing effect to traditionally used desensitizing agent fluoride varnish.
- Trial name
- NCT05569590
- Testing
- Propolis, hydrogen peroxide 35%, fluoride varnish
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118716
- Testing
- Fluticasone propionate/salmeterol, Fluticasone Propionate
- Where
- 50 sites in United States
- Volunteers
- 248 people
- Sponsor
- GlaxoSmithKline
Healthy Volunteer, Hypersensitivity Reactions
Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions
The goal of this clinical trial is to investigate biomarkers of non-IgE-mediated immediate hypersensitivity reactions during infusion of intravenous vancomycin.
- Conditions
- Healthy Volunteer, Hypersensitivity Reactions, Vancomycin
- Trial name
- NCT07605806
- Testing
- Vancomycin (IV)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Type 2 Diabetes
Effect of Gynostemma Pentaphyllum Tea in Insulin Sensitivity in Type 2 Diabetic Patients
The aim of the present study was to investigate the effects of Gynostemma Pentaphyllum tea on insulin sensitivity in drug-naïve type 2 diabetic patients.
- Trial name
- NCT01254084
- Testing
- Gynostemma Pentaphyllum tea
- Where
- 2 sites in Vietnam
- Volunteers
- 16 people
- Sponsor
- Hanoi Medical University
Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia
Ex Vivo Drug Sensitivity Testing and Mutation Profiling
This study is a prospective, non-randomized feasibility study. Freshly isolated tumor cells from patients will be screened using state-of-the-art viability assay designed for ex vivo high-throughput drug sensitivity testing…
- Conditions
- Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Large Cell Lymphoma, Refractory Childhood Acute Lymphoblastic Leukemia
- Trial name
- NCT03860376
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Florida International University
Seasonal Allergic Rhinitis
This Study Contains an Active Drug Treatment Group With Mometasone Furoate Nasal Spray and a Placebo (Dummy) Treatment Group for Seasonal Allergic Rhinitis (SAR). (Study P05073)(COMPLETED)
The purpose of this study is to evaluate how well mometasone furoate nasal spray (MFNS) works to relieve SAR symptoms compared to Placebo when symptoms are induced in a chamber setting.
- Trial name
- NCT00491504
- Testing
- Mometasone Furoate Nasal Spray
- Volunteers
- 310 people
- Sponsor
- Organon and Co
Bronchial Asthma, Adherence, Medication
Cognitive and Emotional Factors Relation to Treatment Adherence in Asthmatic Patients in Upper Egypt
Non-adherence to controller therapy is one of the main reasons of poor asthma control. Adherence to medication in different studies range between 30 and 70% .
- Trial name
- NCT06200623
- Volunteers
- 138 people
- Sponsor
- Entsar Hsanen
Dentin Sensitivity
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex…
- Trial name
- NCT02919202
- Testing
- Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride., Self-etching Dentine Bonding Agent
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Kent
Advanced Pancreatic Neuroendocrine Tumor
In Vitro Organoid Drug Sensitivity-Guided Treatment for Advanced Pancreatic Neuroendocrine Tumor
The purpose of this study is to explore whether chemotherapy and targeted-therapy regimens guided by organoid drug sensitivity test can improve the outcomes of non-resectable locally advanced and metastatic Pancreatic…
- Trial name
- NCT06246630
- Testing
- Chemotherapy and targeted-therapy guided by organoid drug sensitivity test
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ruijin Hospital
Bronchial Asthma
Study of Efficacy of Phenytoin in Therapy of Children With Bronchial Asthma
The purpose of this study was to determine whether antiepileptic drug phenytoin is effective in the treatment of chronic asthma in children.
- Trial name
- NCT00366067
- Testing
- Phenytoin
- Where
- Georgia
- Volunteers
- 50 people
- Sponsor
- Centre of Chinese Medicine, Georgia
Bronchial Asthma
Antiepileptic Drug Carbamazepine in Treatment of Bronchial Asthma
The purpose of this study was evaluation the efficacy of antiepileptic drug carbamazepine in the treatment of mild-to-severe bronchial asthma.
- Trial name
- NCT00207428
- Testing
- Carbamazepine
- Volunteers
- 65 people
- Sponsor
- Centre of Chinese Medicine, Georgia
Asthma
Special Drug Use Investigation for ADOAIR Metered-dose Inhaler (Pediatric)
To investigate possible problems or questions in safety and efficacy of ADOAIR 100 DISKUS and ADOAIR 50 AEROSOL 120 in Japanese pediatric patients with bronchial asthma for a long term under the practical use conditions.
- Trial name
- NCT01332422
- Testing
- Salmeterol and Fluticasone
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Asthma
Effect of a Pharmaceutical Intervention on the Level of Control of the Asthmatic Patient
Measurement of disease control, treatment adherence and patient knowledge of his/her medication in patients that are receiving a pharmaceutical intervention compared with those patients who receive regular pharmaceutical care.
- Trial name
- NCT01085474
- Testing
- 1, 2
- Where
- 2 sites in Spain
- Volunteers
- 384 people
- Sponsor
- AstraZeneca
Asthma
Functional Medicine in Asthma (FAst) Study
This is a pilot, proof of concept, early stage study. The study goal is to determine whether the Functional Medicine approach to the treatment of moderate to severe persistent asthma enhances standard guideline-based care with…
- Trial name
- FAst (NCT02808689)
- Testing
- Lifestyle Factors, Customized use of Dietary Supplements, Currently Accepted Asthma Care Guidelines
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The Cleveland Clinic
Asthma
Phenotyping Responses to Systemic Corticosteroids in the Management of Asthma Attacks
This observational study compares the phenotypic variability (clinical and biological) in treatment response to systemic corticosteroids according to the blood eosinophil count and FeNO in physician-diagnosed ≥12-year-old…
- Trial name
- PRISMA (NCT05870215)
- Testing
- Visit 1: Clinical exam and questionnaires, Visit 1: Respiratory physiology, Visit 1: Inflammometry
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Hypertension
Using Multimedia Technology for Hypertension Control for Low-Income African Americans
The purpose of this study is to test an interactive DVD intervention to encourage patients to stick to their blood pressure medication in order to achieve blood pressure control for African American patients.
- Trial name
- CSI Birmingham (NCT00875225)
- Testing
- DVD, Intervention DVD
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cooper Green Mercy Hospital
Breast Cancer
Implantable Microdevice for In Vivo Drug Sensitivity Testing in Patients With Early Stage, HER2-Positive or Triple Negative Breast Cancer
The purpose of this study is to test the safety and feasibility of placing and removing a small device that contains anti-cancer drugs in a breast tumor of patients who plan on having breast surgery without treatment prior or…
- Trial name
- NCT02521363
- Testing
- KIBUR MICRODEVICE, anthracycline and taxane based chemotherapy
- Where
- 6 sites in United States
- Volunteers
- 11 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.