Clinical trials: Algorithms
Diarrhea Infectious, Algorithms
The Utility and Feasibility of Accessible Diarrhea Etiology Prediction Tool (ADEPT) in an Informal Healthcare Setting
Diarrheal disease remains a leading cause of morbidity and mortality for children under 5 globally. Accepted best practice for managing diarrhea in the absence of blood or suspicion of cholera is rehydration, however in resource…
- Conditions
- Diarrhea Infectious, Algorithms, Decision Support Systems, Clinical, Clinical Decision-making
- Trial name
- NCT07538531
- Testing
- Diagnostic test: Accessible Diarrhea Etiology Prediction Tool (ADEPT)
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Daniel Leung
Postoperative Period, Physical Activity
Post-Operative Physical Activity Monitoring: Algorithm Performance and Clinical Outcomes
The goal of this observational study is to validate physical activity algorithms in post-operative populations through raw accelerometer data collection using the ADI Study Watch 4.5 while in an in-patient setting.
- Conditions
- Postoperative Period, Physical Activity, Wearable Electronic Devices, Algorithms
- Trial name
- NCT06605066
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Alp Ozel
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Defibrillators, Implantable, Follow-Up Studies
Remote Programming of Cardiac Implantable Electronic Device
Cardiac Implantable Electronic Devices (CIEDs) such as pacemakers and implantable cardioverter defibrillators, need to be regularly interrogated and reprogrammed to ensure proper functioning.
- Conditions
- Defibrillators, Implantable, Follow-Up Studies, Pacemaker, Artificial, Telemedicine
- Trial name
- REACT (NCT05366660)
- Testing
- Interrogation/programming
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Bordeaux
Development of the Virtual Biopsy, Tumor Grade
Virtual Biopsy Development to Identify Patient's Glioma Grade at the CHU of Poitiers Using Magnetic Resonance Imaging
Glioma is a tumor of the central nervous system. These lesions are sorted with the WHO ranking regarding the tumoral oncotype. The tumoral MRI assessment is the first step before any medical decision.
- Conditions
- Development of the Virtual Biopsy, Tumor Grade, Artificial Intelligence Algorithms, Clinical
- Trial name
- MR3TGLIOBIOPSY (NCT04313140)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Poitiers University Hospital
Stroke Outcome Prediction Supported by Deep Learning Algorithm
STOP-stroke: STroke Outcome Prediction in the Acute Treatment Setting
The STOP-stroke project aims at improving prediction of outcome early after stroke. In order to achieve this, we need to understand reasons (important variables) for prediction in a real clinical prognostication process.
- Trial name
- STOP-STroke (NCT06534645)
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University of Zurich
Coronary Artery Disease, Coronary Stenosis
Retrospective Algorithm Validation of IVUS-FFR in Patients
This is a retrospective, single-center study to develop and validate an updated algorithm for computing fractional flow reserve from intravascular ultrasound images (IvusFFR v2.0).
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Algorithm Validation for Fractional Flow Reserve Derived From Intravascular Ultrasound
- Trial name
- V-IVUS_FFR (NCT07551518)
- Testing
- No Intervention (Retrospective Data Analysis)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Intensive Care, Mechanical Ventilation
Predictive Algorithms for Critical Rehabilitation Outcomes
An increasing amount of evidence from evidence-based medicine indicates that early rehabilitation intervention for patients receiving mechanical ventilation is safe and feasible, and can promote functional recovery and reduce…
- Conditions
- Intensive Care, Mechanical Ventilation, Rehabilitation, Algorithms
- Trial name
- NCT06532994
- Testing
- Early rehabilitation intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Wuhan University
AI-algorithm Usage
A Prospective Analysis To Assess The Potential Use Of ECGio In Clinical Practice
The goal of this observational study is to learn if an ai-assistive algorithm would be useful in patients who are under suspicion of coronary disease.
- Trial name
- PAPP (NCT07405866)
- Testing
- AI-Assistive Algorithm
- Where
- 4 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Heart Input Output Inc
Coronary Artery Disease (CAD), Artificial Intelligence Algorithms
AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population
This study aims to evaluate the effectiveness of this facial image-based AI algorithm for screening CAD in high-risk community populations (specifically individuals with diabetes, hypertension, or aged over 65).
- Conditions
- Coronary Artery Disease (CAD), Artificial Intelligence Algorithms, Face, Screening
- Trial name
- NCT07277686
- Testing
- No Intervention
- Where
- 3 sites in China
- Volunteers
- 1,392 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Psychological Distress, Develop a Respiration Biosignal Feedback Algorithm
Mindfulness Training and Respiration Biosignal Feedback - Study 1
The goal of this research is to develop a new breathing feature on the meditation app, Equa, to help young adults who are distressed, understand their physiological responses and mindfulness skill development during meditation.
- Conditions
- Psychological Distress, Develop a Respiration Biosignal Feedback Algorithm, Utilize Respiration Algorithm to Predict Mindfulness Skills
- Trial name
- NCT06625697
- Testing
- Mindfulness Meditation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Equa Health
Knee Osteoarthritis, Chitosan Nanoparticles Gel
Extracorporeal Shockwave Versus Phonophoresis Using Chitosan-Nanoparticles Gel on Functional and Anatomical Changes Detected With Artificial Intelligence Based Texture Analysis Algorithm in Knee Osteoarthritis Patients: A Double Blind Randomized Controlled Trial
A parallel double blinded randomized controlled clinical trial (RCT) with a 1:1:1 allocation will be conducted in an orthopedic clinic in Cairo and Giza Governments - Egypt.
- Conditions
- Knee Osteoarthritis, Chitosan Nanoparticles Gel, Artificial Intelligence Texture Analysis Bases Algorithm, Subchondral Bone Changes (Anatomical Changes)
- Trial name
- NCT06567301
- Testing
- Ultrasound therapy combined with Chitosan nanoparticles gel
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Describe Typical Gray Scale/Color Doppler Ultrasound Features of Gestational Trophoblastic Neoplasia at the US Examination, To Assess if There Are Differences at the Baseline US Scan Between Low-risk and High-risk Patients
Gestional Trophoblastic Neoplasia Ultrasound Assessment: Titanium Study
Gestational trophoblast diseases are characterized by abnormal proliferation of trophoblastic tissue, which can occur consequent to any pregnancy event.
- Conditions
- Describe Typical Gray Scale/Color Doppler Ultrasound Features of Gestational Trophoblastic Neoplasia at the US Examination, To Assess if There Are Differences at the Baseline US Scan Between Low-risk and High-risk Patients, To Identify Ultrasound Predictors of Resistance to First-line Single Drug Chemotherapy in Low-risk GTN Patients, To Investigate if Machine Learning (ML) Algorithms (Radiomics, Deep Neural Networks (DNN), and Other Machine Learning Algorithms
- Trial name
- TITANIUM (NCT06284980)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Prediction Hypothyroidism Patients Using Machine Learning Algorithms, Identification of Important Symptoms of Hypothyroidism
Identification of Important Symptoms and Diagnostic Hypothyroidism Patients Using Machine Learning Algorithms
Hypothyroidism (HT) is one of the most common endocrine diseases. It is, however, usually challenging for physicians to diagnose due to non-specific symptoms. The usual procedure for diagnosis of HT is a blood test.
- Trial name
- NCT06112886
- Testing
- There was no intervention in this study
- Where
- Iran
- Volunteers
- 1,296 people, healthy volunteers welcome
- Sponsor
- Kerman University of Medical Sciences
COPD, Cough
A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm for COPD
Cough is one of the most common symptoms in COPD patients, and its different characteristics in amplitude, frequency and waveform can be analyzed by intelligent algorithms for the auxiliary diagnosis of COPD.
- Conditions
- COPD, Cough, Algorithm
- Trial name
- NCT06082791
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Energy Metabolism, Algorithms
Estimation of Energy Expenditure and Physical Activity Classification With Wearables
Regular physical activity (PA) is proven to help prevent and treat several non-communicable diseases such as heart disease, stroke, and diabetes.
- Trial name
- EEPAC (NCT05523830)
- Testing
- No Intervention
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Upper Extermity Spasticity, Multidisciplinary Approach
Surgery and Neuroablative Procedures in Spasticity
For many patients with spasticity, traditional therapies have not achieved maximal outcomes. Due to common complaints such as pain, limb positioning and hygiene concerns, there has been an increase demand for other adjunctive…
- Conditions
- Upper Extermity Spasticity, Multidisciplinary Approach, Novel Algorithm, Diagnostic Nerve Block
- Trial name
- NCT04670783
- Testing
- Surgery
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Vancouver Island Health Authority
Algorithm Verification
mCVI Confirmatory Clinical Study: Algorithm Verification With Healthy Volunteers
This single center confirmatory clinical study is to verify the algorithm of mCVI® to accurately capture pulse rate and respiratory rate in 20 healthy subjects in comparison to traditional measurements of the Nonin Lifesense…
- Trial name
- NCT05233319
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Intelomed, Inc.
Imaging Data Collection From Dynamic Swallowing MRI in Healthy Volunteers, Create Operating Algorithms
Transposition of Dynamic MRI Data From Healthy Subjects to an in Vitro Swallowing Simulator
Swallowing is a complex process, involving a very fine synchronization of the pharyngo-larynx, with respiration, under the control of the central nervous system and numerous peripheral effectors.
- Conditions
- Imaging Data Collection From Dynamic Swallowing MRI in Healthy Volunteers, Create Operating Algorithms, Apply the Imaging Data of MRI to a Swallowing Simulator
- Trial name
- SWALL-E (NCT05178108)
- Testing
- Real-time MRI of swallowing
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Algorithm for Cervix Carcinoma Screening
Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus
Cervix carcinoma has been a serious, long-term issue in the Czech Republic. The cause of nearly all cervix carcinomas is human papilomavirus (HPV).
- Trial name
- LIBUSE (NCT05578833)
- Testing
- HPV DNA test with selective HPV 16/18 genotyping (cobas® 4800 HPV Test, Roche), p16 and Ki-67 biomarker detection in the form of dual cytological staining (CINtec Plus, Roche), standard conventional cytology PAP test
- Where
- Czechia
- Volunteers
- 2,426 people
- Sponsor
- AeskuLab Pathology Prague