Clinical trials: Alcohol Misuse
HIV (Human Immunodeficiency Virus), Alcohol Misuse
PNF RCT to Decrease Alcohol Use and Increase HIV Prevention
Randomized controlled trial to test the preliminary efficacy and mediating mechanism of a personalized normative feedback intervention on behavioral intentions, heavy alcohol use, and HIV/STI prevention among adolescents and…
- Conditions
- HIV (Human Immunodeficiency Virus), Alcohol Misuse, STI
- Trial name
- NCT07731932
- Testing
- PNF - HIV norms, PNF - Alcohol use norms, PNF - HIV and alcohol use norms
- Where
- Uganda
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Alcohol Misuse, Cannabis Misuse
Substance Use in Assault-Injured Young Adults
This study aims to improve a short motivational conversation to better help young adults who were injured in assaults and also use alcohol or cannabis.
- Trial name
- NCT07070414
- Testing
- Brief Negotiation Interview intervention (BNI) (adapted)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Sleep, Alcohol Misuse
Mechanisms of Cannabidiol and Sleep in the Context of Alcohol Use
The goal of this clinical trial is to learn if cannabidiol helps to improve sleep and decrease alcohol use. It will also learn about the safety of cannabidiol.
- Trial name
- CALM (NCT07527338)
- Testing
- Cannabidiol
- Volunteers
- 58 people
- Sponsor
- University of Colorado, Boulder
Depression, Alcohol, Drinking
Expressive Writing for Co-Occurring Depression and Alcohol Misuse
***Please note that this study does not offer comprehensive treatment program for alcohol abuse or depression. Please do not contact the study staff if you are seeking psychological treatment.
- Trial name
- NCT00818636
- Testing
- Expressive writing (in addition to group therapy as usual).
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Baylor College of Medicine
Liver Diseases, Alcoholic, Alcohol Use Disorder
Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controlled Trial
To evaluate the efficacy of systematically offering newly diagnosed ALD patients to AUD treatment, in the hepatology clinic, on alcohol abstinence after 6 months.
- Conditions
- Liver Diseases, Alcoholic, Alcohol Use Disorder, Treatment Adherence, Alcoholism
- Trial name
- NCT06493773
- Testing
- Offer of specialized alcohol use disorder treatment in the hepatology clinic
- Where
- Denmark
- Volunteers
- 221 people
- Sponsor
- Zealand University Hospital
Alcohol Use Disorder
Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment
Internet-delivered cognitive behaviour therapy (ICBT) shows promise as a method of treating alcohol misuse. In this form of treatment, patients complete online lessons over several weeks that assist patients in developing skills…
- Trial name
- NCT04611854
- Testing
- Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Regina
Psychosis, Alcohol Use Disorder
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in…
- Conditions
- Psychosis, Alcohol Use Disorder, Cannabis Use Disorder
- Trial name
- NCT07056894
- Testing
- Action-Based Cognitive Remediation
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Healthy
Endophenotype for Alcohol Misuse in Healthy Minority Populations
The purpose of the study is to understand the relationship between what an individual inherited from their family (genetics), how they respond and feel after drinking alcohol, and how they respond to pre-treatment with…
- Trial name
- DEFINE (NCT00256451)
- Testing
- Naltrexone, alcohol
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Misuse, Sexual Assault
Positive Change for Sailors
Alcohol use and sexual violence are significant public health issues affecting military personnel. This study includes a pilot randomized control trial of Positive Change© for Sailors, an integrated alcohol and sexual assault…
- Trial name
- +Change Sailor (NCT07858305)
- Testing
- Positive Change© for Sailors
- Where
- 4 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Naval Health Research Center
Alcohol Misuse, HIV
Gathering Online for Dialogue and Discussion to Enhance Social Support
The goal of this trial is to test a modified mobile health intervention (with a group component) relative to a mobile health intervention in a two-arm randomized trial with up to 500 young women who are human immunodeficiency…
- Conditions
- Alcohol Misuse, HIV, Sexually Transmitted Infections, Pre-exposure Prophylaxis
- Trial name
- GODDESS (NCT05753683)
- Testing
- mHealth-Women's CoOp, Virtual Group
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Alcohol Use, Cannabis Use
MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education
The MATAspire intervention is a web-app designed to promote substance misuse prevention education and bolster protective coping skills whereby students complete six weekly interactive modules using a smart device or computer.
- Conditions
- Alcohol Use, Cannabis Use, Nicotine Use, Illicit Drug Use
- Trial name
- MATAspire (NCT06553196)
- Testing
- MATAspire Web-app
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Alcohol Consumption, Alcohol Abuse/Dependence
Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults
The purpose of this study is to understand social contexts and alcohol use. We hope to learn how being around peers affects alcohol consumption in young adults.
- Trial name
- PALS (NCT06627803)
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Anxiety Sensitivity, Hopelessness
The UniVenture Program
UniVenture is a research partnership with one common goal: to adapt, test, and begin sharing an effective, sustainable, targeted wellness program to tackle the timely social issue of heavy drinking and other substance misuse on…
- Conditions
- Anxiety Sensitivity, Hopelessness, Sensation Seeking, Impulsivity
- Trial name
- NCT05383989
- Testing
- UniVenture Hopelessness manual, UniVenture Anxiety Sensitivity manual, UniVenture Sensation Seeking manual
- Where
- 5 sites in Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sherry Stewart
Alcohol Misuse
Brief Alcohol Treatment for Women Veterans in Primary Care
The goal of this study is to develop and test a brief behavioral treatment for women Veterans with alcohol use in primary care. The study involves a development phase, an open trial phase, and a pilot randomized controlled trial.
- Trial name
- NCT07414589
- Testing
- Brief, Integrated Intervention for Women Veterans with Unhealthy Alcohol Use in Primary Care, Primary care usual care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Syracuse VA Medical Center
Drug Overdose, Substance Abuse
EEG Monitoring in the Emergency Department
This study seeks to investigate whether drug effects in suspected overdose patients could be identified using the electroencephalogram (EEG).
- Conditions
- Drug Overdose, Substance Abuse, Alcohol Abuse
- Trial name
- NCT04070521
- Testing
- Observational EEG Monitoring
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Alcoholism
Evaluation of Physical Activity of Patients Admitted to Addiction Service
Addiction is a public health issue that affects nearly 30% of French people according to INSEE. For several years now, the investigators have known that sport is a real help in the fight against addictions, with recent medical…
- Trial name
- ACTP-ADDICT (NCT04953403)
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Montpellier
Alcohol Use Disorder, Risk Behavior, Health
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use.
- Conditions
- Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
- Trial name
- SEAL (NCT06005298)
- Testing
- Screening, Brief Intervention, Referral to Treatment (SBIRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shirish S Barve
Alcohol Consumption
Pilot Study of a Computer-Based Intervention for Alcohol Misuse in the Emergency Department
Alcohol misuse amongst youth is a significant clinical and public health problem. The Emergency Department (ED) is an important setting for the treatment of alcohol-related problems as it is often the first point of contact…
- Trial name
- NCT01146665
- Testing
- Computer-based PAF
- Where
- 3 sites in Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alberta
MBSR, Young Adults
A Reinforced Mindfulness-Based Intervention to Reduce Problematic Drinking Among Hispanic Emerging Adults
This study is a trial to evaluate a mindfulness program designed for Hispanic young adults. Participants will be randomly assigned to one of two groups: (1) an in-person, 8-week mindfulness program (one 1.5-hour session per week…
- Conditions
- MBSR, Young Adults, Heavy Episodic Drinking
- Trial name
- Mindfulness (NCT07192094)
- Testing
- Mindfulness Sessions - 8 Week Program
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Florida International University
Alcohol Misuse, Hypertension
Telehealth Treatment of Veterans With Alcohol Misuse at Risk for Cardiovascular Disease
The primary objective of this project is to refine a cognitive-behavioral intervention for comorbid alcohol misuse and modifiable CVD risk with diverse stakeholder input, so that the intervention can be deployed within existing…
- Conditions
- Alcohol Misuse, Hypertension, Elevated Cardiovascular Risk
- Trial name
- ACME-TM (NCT04838457)
- Testing
- Alcohol and CVD Management and Engagement through Telehealth and mHealth (ACME-TM)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development