Clinical trials: Akinesia
Parkinson's Disease
Subthalamic Nucleus, Akinesia and Parkinson's Disease
This program aims to understand the role of the subthalamic nucleus in the control of the movement in healthy humans and patients with Parkinson's disease, how the STN dysfunction contributes to akinesia and how the STN…
- Trial name
- GB-MOV (NCT01682668)
- Testing
- Bilateral subthalamic stimulation
- Where
- 2 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Quality of Ocular Akinesia (Onset and Duration)
Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract Surgery
There are several local anesthetic techniques available for cataract surgery and the choice depends on patient, surgical and operator factors.
- Trial name
- NCT03243500
- Testing
- Atracurium, Lidocaine 2%, Bupivacaine 0.5%
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Kasr El Aini Hospital
Parkinson's Disease, Motor Symptoms
Apokyn for Motor IMProvement of Morning AKinesia Trial (AM IMPAKT)
This study is designed to assess the effect of APOKYN treatment in rapid and reliable improvement of motor symptoms in Parkinson's disease (PD) subjects suffering from delayed or unreliable onset of levodopa (L-dopa) action.
- Conditions
- Parkinson's Disease, Motor Symptoms, Akinesia, Hypomobility
- Trial name
- AM IMPAKT (NCT01770145)
- Testing
- APOKYN, L-dopa, Trimethobenzamide
- Where
- 12 sites in United States
- Volunteers
- 127 people
- Sponsor
- MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals
Strabismus, Regional Anesthesia Morbidity
Peribulbar Rocuronium in Adult Strabismus Surgery
This is a prospective randomized clinical study that will be carried on adult patients aged from 21-60 years and presented for strabismus surgery under peribulbar anesthesia.
- Conditions
- Strabismus, Regional Anesthesia Morbidity, Rocuronium
- Trial name
- NCT04821817
- Testing
- Normal saline, Rocuronium
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Tanta University
Bradykinesia, Parkinson Disease
Movement Disorders Analysis Using a Deep Learning Approach
Bradykinesia is a key parkinsonian feature yet subjectively assessed by the MDS-UPDRS score, making reproducible measurements and follow-up challenging.
- Conditions
- Bradykinesia, Parkinson Disease, Hypokinesia, Akinesia
- Trial name
- NCT04974034
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Avicenne
Parkinson's Disease
Azilect® In Wearing-Off (AIWO)
End-of-dose fluctuations e. g. wearing-off are defined as a recurrence of motor and non-motor Parkinson's Disease (PD) symptoms that precedes a scheduled dose and improves with the next dose of anti-parkinsonian medication.
- Trial name
- AIWO (NCT02384512)
- Testing
- Azilect®
- Where
- 140 sites in Germany
- Volunteers
- 261 people
- Sponsor
- Teva Pharma GmbH
Cataract Surgery, Patient Satisfaction
Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surgery
It is aimed to determine patient satisfaction (pain assessment during and after the operation) and the initial and total anesthesia durations of eye lid and globe anesthesia after administration of local anesthetic solution only…
- Conditions
- Cataract Surgery, Patient Satisfaction, Akinesia, Anesthesia, Local
- Trial name
- NCT04178200
- Testing
- Lidocaine 2% Injectable Solution 0.75 ml, Bupivacaine Hcl 0.5% Inj 0.75 ml, Lidocaine 2% Injectable Solution 1.5 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Develi Devlet Hastanesi
Parkinson Disease
EEG and Pharmacological Exploration of Executive Dysfunctions Induced by STN-DBS in PD
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) remarkably improves motor functions in patients with Parkinson disease (PD).
- Trial name
- EEGDBSNAd (NCT01796483)
- Testing
- Clonidine (Catapressan)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon