Clinical trials: Airway Extubation
ARDS (Acute Respiratory Distress Syndrome)
Pressure Release Ventilation Compared to Lung Protective Ventilation in Moderate and Severe ARDS
This study compares two different ways of providing mechanical ventilation to patients with moderate to severe acute respiratory distress syndrome (ARDS), a serious condition in which the lungs become inflamed and make it…
- Trial name
- NCT07803614
- Testing
- Arm 1 Intervention Name: Low-Tidal-Volume Ventilation (LTV)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Koot Ahmad
Anesthesia, Intravenous, Laparotomy
TCI vs Manually Controlled Infusion of Propofol
Anesthesia records for patients anesthetized with target controlled infusion of propofol and remifentanil will be matched with patients anesthezied with manyally controlled infusion.
- Conditions
- Anesthesia, Intravenous, Laparotomy, Airway Extubation
- Trial name
- NCT04266535
- Testing
- Target controlled infusion
- Volunteers
- 40 people
- Sponsor
- Regional Hospital West Jutland
Airway Stress Response
Dexmedetomidine vs Labetalol for Airway Stress in Hypertensive Craniotomy Patients
This randomized trial compares dexmedetomidine and labetalol in controlling airway and hemodynamic stress during extubation in hypertensive patients undergoing craniotomy.
- Trial name
- NCT07034898
- Testing
- Dexmedetomidine, Labetalol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Complications, Pulmonary
Laryngeal Mask Airway Facilitates a Safe and Smooth Emergence From Anesthesia in Patients Undergoing Craniotomy
Stabilizing hemodynamic and reducing pulmonary complications during extubation with switching endotracheal tube to laryngeal mask in craniotomies
- Trial name
- NCT05253404
- Testing
- Ambu® AuraOnce™ Disposable Laryngeal Mask
- Where
- Taiwan
- Volunteers
- 62 people
- Sponsor
- Chang Gung Memorial Hospital
Emergence From Anesthesia, Mechanical Ventilation
Controlled Ventilation During Anesthetic Emergence
Absolutely - for a ClinicalTrials.gov-style Brief Summary, I'd keep it simple and patient-friendly like your example: The goal of this clinical trial is to learn whether maintaining controlled mechanical ventilation during…
- Trial name
- NCT07853547
- Testing
- Controlled/Full-Support Mechanical Ventilation During Emergence
- Where
- Saudi Arabia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Bronchopulmonary Dysplasia
Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator
Very premature infants often cannot breathe on their own and require assistance with a respirator. Conventional respirators deliver air or oxygen via a breathing tube placed through the mouth to the airway (endotracheal tube).
- Trial name
- NCT01440647
- Testing
- Extubation to NIPPV, Extubation to CPAP
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Intubation Complication, PreTerm Birth
NIPPV Versus Bi-level Nasal Continuous Positive Airway Pressure Following Extubation
Mechanical ventilation is important in the care of preterm infants with respiratory failure, but may be associated with lung injury. Efforts are needed to avoid or minimize the use of mechanical ventilation.
- Trial name
- NCT02842190
- Testing
- NIPPV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 Grams
The purpose of this study is to compare two methods of delivering Nasal Continuous Airway Pressure (NCPAP): Biphasic Mode and a continuous mode, to see which is better in getting babies off the ventilator and decreasing lung…
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Apnea of Prematurity
- Trial name
- NCT00308789
- Testing
- Biphasic Infant flow NCPAP, CPAP
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Mount Sinai Hospital, Canada
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Neonatal Respiratory Failure
Non Invasive Ventilation Versus Continuous Positive Airway Pressure After Extubation of Very Low Birth Weight Infants.
The purpose of this study is to determine whether Nasal intermittent positive pressure ventilation (NIPPV) non synchronized is better than continuous positive airway pressure (NCPAP)in preventing extubation failure within 72 h…
- Trial name
- VNINS (NCT01778829)
- Testing
- CPAP ventilation mode, NIPPV ventilation mode
- Where
- Chile
- Volunteers
- 220 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Respiratory Failure
The Efficacy of the Whisperflow CPAP System Versus Nasal High Flow in Patients at High Risk for Postextubation Failure
The purpose of this study is to compare the effect of continuous positive airway pressure (CPAP) delivered by the variable generator WhisperFlow System with high flow nasal cannula oxygen therapy in mechanically ventilated…
- Trial name
- NCT02918786
- Testing
- Nasal high-flow, CPAP
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Ramathibodi Hospital
Respiration, Artificial, COVID-19
Characteristics of Weaning From Mechanical Ventilation in COVID-19
This report is a multicenter, observational, analytical and prospective study. The objective was to describe the weaning of mechanical ventilation in patients with SARS-CoV-2 and the clinical results according to the different…
- Trial name
- CovWean (NCT05049200)
- Where
- 2 sites in Argentina
- Volunteers
- 326 people
- Sponsor
- Sanatorio Anchorena San Martin
Preterm Infant
Cardiorespiratory Effects of "Higher" Versus "Equivalent" CPAP Upon Extubation From High EAP in Preterm Infants
The aim of this study is to compare the cardiovascular and respiratory effects of "higher" versus "equivalent" CPAP pressures post-extubation from high endotracheal airway pressures (EAP), defined as at least 8 cm H2O (water), in…
- Trial name
- CO-PAP (NCT02528851)
- Testing
- Extubation from endotracheal mechanical ventilation to CPAP
- Volunteers
- 14 people
- Sponsor
- McMaster University
Mechanical Ventilation, Pneumonia
Removal of Endotracheal Tube Secretions Comprehensively Until Extubation
The purpose of this study is to measure secretion accumulation within endotracheal tubes of mechanically ventilated patients and test the efficacy, safety and clinical impact of removing the secretions using novel airway…
- Trial name
- RESCUE (NCT00663637)
- Testing
- CAM (Complete Airway Management) Catheters
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- O. M. Neotech, Inc.
Perioperative/Postoperative Complications, PORC (Postoperative Residual Curarization)
A Study of Residual Curarization Incidence in China
The purpose of this study is to determine the incidence of residual curarization in PACU and relevant risk factors.
- Trial name
- NCT01690338
- Testing
- Vecuronium Bromide, Rocuronium, Cisatracurium
- Where
- 22 sites in China
- Volunteers
- 6,090 people
- Sponsor
- Peking University First Hospital
Airway Complication of Anesthesia
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
The main objective of this study was to investigate whether propofol assisted extubation could reduce the incidence of respiratory adverse events in children with tonsil adenoidectomy.
- Trial name
- NCT05769842
- Testing
- propofol, normal saline
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Children's Hospital of Fudan University
Invasive Mechanical Ventilation, Extubation Time
Measurement of Efferent Neural Drive From Respiratory Centers to Upper Airways Using Electromyography (EMG) of Genioglossus (GG) in Patients Dependent on Invasive Mechanical Ventilation
Muscle activity in the upper airway is influenced by specific states such as anesthesia, sleep, wakefulness, and the phases of respiration.
- Trial name
- NCT07842484
- Testing
- electromyography (EMG) of genioglossus (GG)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Non-inferiority, in Terms of Extubation Failure, Continuation of Enteral Nutrition Before Extubation Versus Gastric Vacuity Peri-extubation
Non-inferiority Study of the Pursuit of Enteral Nutrition Compared to a Strategy of Gastric Emptiness Peri-extubation. Cluster Randomized Trial
Approximately 50 to 60% of ICU patients are subjected to invasive mechanical ventilation-through a tracheal tube. Extubation consists of a key moment for the patient on the road to recovery (1).
- Trial name
- AMBROISIE (NCT03335345)
- Testing
- maintaining calorie intake, maximum gastric vacuity
- Where
- 22 sites in France, Guadeloupe
- Volunteers
- 1,148 people
- Sponsor
- Centre Hospitalier le Mans
Airway Extubation, Pneumonia, Bacterial
Relation Between the Volume of Subglottic Secretion and Risk of Extubation Failure in ICU Patients (SEGEX)
This study evaluates the relation between the volume of subglottic secretion before airway extubation and the risk of extubation failure in the ICU patient.
- Conditions
- Airway Extubation, Pneumonia, Bacterial, Aspiration of Subglottic Secretions
- Trial name
- SEGEX (NCT03946371)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Airway Complication of Anesthesia, Respiratory Complications of Care
Comparison of Deep Versus Awake Tracheal Extubation in Adults
Prospective, randomized, single-blinded controlled study to compare the airway and respiratory complications of deep and awake tracheal extubations in adults.
- Trial name
- CDATE (NCT05361850)
- Testing
- Extubation
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- United States Navy