Clinical trials: Air Trapping
Chronic Obstructive Pulmonary Disease
Correlation Between Handgrip Strength and Air Trapping in Patients with Stable Chronic Obstructive Pulmonary Disease
The goal of this observational study is to investigate the relationship between handgrip strength and air trapping in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT06220851
- Testing
- Handgrip strength
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Thammasat University
Cystic Fibrosis
Use of Capnography for the Follow-up of Cystic Fibrosis Children
The respiratory system involvement in cystic fibrosis(CF) influences the prognosis and course of disease. Respiratory assessment is based on spirometry, but its main parameter, the maximal expiratory volume in the first second…
- Trial name
- MUCOCAP (NCT04814797)
- Testing
- Capnography data included in Lung Clearance Index measurement
- Where
- 2 sites in France
- Volunteers
- 76 people
- Sponsor
- Central Hospital, Nancy, France
COPD
The Efficacy of Fluticasone Furoate/Vilanterol/Umeclidinium Compared With Vilanterol/Umeclidinium in Reducing Air Trapping and Airway and Blood Cytokine Levels in COPD
This study aims to demonstrate the effects of triple therapy (ICS/LABA/LAMA) and dual bronchodilators (LAMA/LABA) on air trapping in the lungs' COPD patients and inflammatory mediators
- Trial name
- NCT06474039
- Testing
- Trelegy or Anoro
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Chronic Obstructive Pulmonary Disease
Continuous Positive Airway Pressure Effect on Air Trapping in Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease is a disease characterized by small airways inflammation and obstruction. The small airways disease produces hyperinflation (air trapping), which increases with exercise.
- Trial name
- CPAP (NCT01507844)
- Testing
- positive ventilation
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Assaf-Harofeh Medical Center
Emphysema or COPD
Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema
The goal of this clinical trial is to test the feasibility of an implant for severe emphysema in up to 30 participants at up to 5 study centers located in Europe and the United Kingdom.
- Trial name
- BREATHE-2 (NCT05949645)
- Testing
- Apreo Implant Group
- Where
- 3 sites in Austria, Netherlands and 1 more
- Volunteers
- 30 people
- Sponsor
- Apreo Health, Inc.
Emphysema or COPD
First in Human Study to Assess an Implant to Treat Severe Emphysema
The goal of this clinical trial is to test the feasibility of an implant for severe emphysema in up to 30 participants. The main questions it aims to answer are: Is it safe? Does it work? Participants who meet eligibility…
- Trial name
- BREATHE-1 (NCT05854550)
- Testing
- Apreo Implant Group
- Where
- 2 sites in Australia
- Volunteers
- 48 people
- Sponsor
- Apreo Health, Inc.
COPD, Emphysema
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphysema suffering from dyspnea…
- Trial name
- BREATHE-3 (NCT06891755)
- Testing
- Apreo BREATHE Airway Scaffold, Optimal Medical Management (OMM)
- Where
- 23 sites in United States, Austria and 3 more
- Volunteers
- 250 people
- Sponsor
- Apreo Health, Inc.
Asthma
CT Air-trapping for the Early Identification of Benralizumab Responders Among Eosinophilic Asthma Patients
BenraliScan aims to obtain thoracic computed tomography imaging data to predict the future level of patient response to a monoclonal antibody.
- Trial name
- BenraliScan (NCT03976310)
- Testing
- 48 weeks of Benralizumab, Computed tomography
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Montpellier
Non-small Cell Lung Cancer
Complication and Lung Function Impairment Prediction Using Perfusion and CT Air Trapping
The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be…
- Trial name
- CLIPPCAIR (NCT03885765)
- Testing
- Predictive data, Lung resection
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Montpellier
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Hyperinflation
Effect of Simeox® on Residual Volume in COPD Patients With Pulmonary Hyperinflation
Brief Summary People with severe chronic obstructive pulmonary disease (COPD) often have too much air trapped in their lungs (pulmonary hyperinflation). This makes it hard to breathe and reduces quality of life.
- Trial name
- SIMEO-RV COPD (NCT07665931)
- Testing
- Simeox
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
COPD, COPD Exacerbation
Clinical Feasibility of a Non-invasive Wearable Acoustic Device for Measuring Air Trapping in COPD
This is a pilot observational study during which the investigators will conduct a longitudinal assessment of air trapping (with up to 2 visits) in 40 patients with COPD and variable degrees of air trapping and 20 healthy controls…
- Trial name
- NCT04450368
- Testing
- Sylvee
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Respira Labs, Inc
Asthma
Inflammatory, Functional and Image Composite Measure to Define Asthma Control
The goals of control status of asthma have been changed with the improvement of its management as a chronic disease; many steps should be taken to achieve asthma control as defined by the GINA/NIH guidelines.
- Trial name
- APITA (NCT00597064)
- Testing
- prednisone
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of São Paulo
Secondhand Smoke, Air Trapping
Secondhand Smoke Respiratory Health Study
Exposure to secondhand tobacco smoke (SHS) is associated with diverse health effects in nonsmokers. Flight attendants (FA) who worked on commercial aircraft before the ban on tobacco smoking (exposed FAs) had high, long-term…
- Conditions
- Secondhand Smoke, Air Trapping, Tobacco, Airflow Limitation
- Trial name
- NCT02797275
- Testing
- Albuterol
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
Quality of Life, Exercise
The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise
Treatment of COPD patients depends on the stage of the disease. First of all it is strongly recommended quit smoking, then bronchodilators drugs are added.
- Trial name
- NAC (NCT00476736)
- Testing
- Effect on small airways (N-Acetylcystein)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center