Clinical trials: Agreement
Hypopituitarism
Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone Deficiency
This study tested whether a dose regimen of growth hormone based on body weight is equivalent or better than starting with a low dose and gradually increasing the dose according to individual patient needs.
- Trial name
- NCT00490191
- Testing
- Somatropin
- Where
- 26 sites in United States, France and 4 more
- Volunteers
- 387 people
- Sponsor
- Eli Lilly and Company
Proximal Humerus Fracture
Hanover Humerus Registry
This register study collects data of patients with proximal humerus and humerus shaft fractures to monitor the healing process by assessing shoulder function and quality of life according to the treatment method (operative or…
- Trial name
- HHR (NCT03060876)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Peptic Ulcer
The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients
This study assessed the effect of tailored eradication therapy according to Clarithromycin resistance in Helicobacter pylori patients.
- Trial name
- NCT02648659
- Testing
- Ilaprazole, Amoxicillin, Clarithromycin
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
Infection, Human Immunodeficiency Virus I
ZIAGEN® Post-marketing Surveillance
An open label, multi-centre, non-interventional post-marketing surveillance (PMS) to monitor the safety and efficacy of ZIAGEN® administered in Korean patients according to the prescribing information.
- Trial name
- NCT01205243
- Testing
- ZIAGEN®
- Where
- South Korea
- Volunteers
- 671 people
- Sponsor
- ViiV Healthcare
Meningococcal Disease
Safety of One Dose of Meningococcal ACWY Conjugate Vaccine in Subjects From 2 Months to 55 Years of Age in the Republic of South Korea
A multicenter, single arm, post-marketing surveillance study. This study is a postlicensure requirement of the Korea Food and Drug Administration (KFDA) to provide continued safety evaluation of MenACWY in the Korean population…
- Trial name
- NCT01766206
- Testing
- MenACWY-CRM (Menveo)
- Where
- 54 sites in South Korea
- Volunteers
- 3,948 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Therapeutic Drug Monitoring, Subarachnoid Hemorrhage
Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC)
A recent prospective observational clinical study conducted in an intensive care unit of a third level US university hospital showed that 94% of patients with ES and 50% of those with EC had an ARC for a duration of at least one…
- Conditions
- Therapeutic Drug Monitoring, Subarachnoid Hemorrhage, Intracerebral Hemorrhage
- Trial name
- TANDEM (NCT04132115)
- Testing
- Piperacillin/tazobactam, Meropenem, Daptomycin
- Where
- 2 sites in Italy
- Volunteers
- 104 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Head and Neck Cancer, Oral Cavity Cancer
Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site Sequelae
This is a phase 1b, multicenter, non-randomized prospective study involving an innovation phase (IDEAL-1) followed by a prospective development phase (IDEAL-2A) designed to evaluate the safety and feasibility of…
- Conditions
- Head and Neck Cancer, Oral Cavity Cancer, Oropharynx Cancer
- Trial name
- LAMBEAU STEPA (NCT05757817)
- Testing
- Oropharyngeal or oral cavity reconstruction
- Where
- 4 sites in France
- Volunteers
- 40 people
- Sponsor
- Institut Claudius Regaud
Cataract
Evaluation of the Age-Related Eye Disease Study (AREDS) Clinical Lens Grading System
This study will evaluate a system developed to grade the severity of age-related cataract, a common cause of vision loss in older adults.
- Trial name
- NCT00078299
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Eye Institute (NEI)
HIV Testing
Implementation and Evaluation of an Electronic Alert to Encourage Targeted Screening for HIV Infection at Foch Hospital According to Socio-demographic Criteria
In 2013 in France, 29,000 people are reported to be unaware of their HIV status. HIV testing is a priority in France where one third of all diagnoses remain late despite 5 million annual tests.
- Trial name
- POP-UP (NCT03991767)
- Testing
- "POP-UP" electronic alert, Serology HIV
- Where
- France
- Volunteers
- 297 people
- Sponsor
- Hopital Foch
Multiple Myeloma (MM)
Validating DW-MRI and Fat Fraction in Multiple Myeloma Post-ASCT: The RAC-FAT Study"
This is a multicenter, observational, retrospective-prospective study designed to validate the predictive role of advanced imaging in patients with newly diagnosed multiple myeloma (NDMM).
- Trial name
- NCT07746232
- Testing
- DW-MRI (MY-RADS/RAC score), Fat Fraction (rFF%), Clinical Data Collection
- Where
- 10 sites in Italy
- Volunteers
- 92 people
- Sponsor
- Fondazione EMN Italy Onlus
Bone Marrow Fibrosis
Ruxolitinib vs Allogeneic SCT for Patients With Myelofibrosis According to Donor Availability
The present study will be a multicenter, prospective phase II-study comparing efficacy of allogeneic SCT for patients with myelofibrosis who have a suitable stem cell donor after a 3 months Ruxolitinib induction therapy with…
- Trial name
- NCT03333187
- Testing
- Allogeneic stem cell transplantation, Ruxolitinib continuous therapy
- Where
- 14 sites in Germany
- Volunteers
- 87 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
FATIGUE, Sleep Deprivation
MONITORING OF ATTENTION ACCORDING TO FATIGUE IN THE HEALTHY SUBJECT
To develop an easy-to-use measurement tool for monitoring fatigue and alertness, particularly in sleep-deprived subjects.
- Trial name
- MOTIVATES (NCT05531734)
- Testing
- NaoX Intra-Auricular Device (IAD) monitoring EEG data, Simple psychometric tests
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Seizures
Seizure Identification on the Intensive Care Unit (ICU)
The aim of this project is to assess the ability of different groups of National Heath Service (NHS) professionals to correctly identify clinical seizures, and distinguish them from other movements commonly seen in the ICU…
- Trial name
- NCT07136298
- Testing
- Clinical Opinion
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Breast Neoplasm Female
Concordance of the IHC4 Score Performed in Local or Central Laboratory to Endopredict in ER+/HER2- Breast Cancer
Retrospective observational, multicentric study assessing the immunohistochemistry (IHC) based test IHC4 score in infiltrating early breast cancer: comparison of the score performed in local laboratory vs in a central laboratory…
- Trial name
- GEFPICS IHC4 (NCT04246606)
- Testing
- IHC4 score
- Where
- France
- Volunteers
- 155 people
- Sponsor
- UNICANCER
Alzheimer's Disease
Evaluate the Concordance Between PET Imaging of [18F]-APN-1607 Injection and Postmortem Brain Tissue Tau Pathology in Individuals With HV and MCI or AD.
1. To evaluate the diagnostic performance of [18F]-APN-1607 injection PET imaging in detecting uptake patterns consistent with AD neuropathological changes as defined by the National Institute on Aging-Alzheimer's Association…
- Trial name
- NCT07752784
- Testing
- [18F]-APN-1607
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- JYAMS PET Research & Development Limited
Glaucoma, Retinal Disease
Agreement and Precision Study of the Nidek Mirante
This study is a prospective comparative, randomized, single center study to gather agreement and precision of the Nidek Mirante OCT with SLO and Anterior Segment Imaging capabilities in comparison to the Optovue RTVue XR Avanti…
- Conditions
- Glaucoma, Retinal Disease, Corneal Disease
- Trial name
- NCT04318132
- Testing
- Nidek Mirante, Optovue RTVue XR Avanti, Optos P200DTx
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Anesthesia, Hypoxemia
COMparison of Portable Fingertip Versus Conventional Pulse OximeteRs Trial
Perioperative non-invasive measurement of a patient's peripheral arterial oxygen saturation has become an accepted standard of care endorsed by anaesthesiologists and their regulatory bodies throughout the world.
- Trial name
- COMFORT (NCT03496493)
- Testing
- All patients
- Where
- South Africa
- Volunteers
- 220 people
- Sponsor
- University of Cape Town
SARS-CoV2 Infection, COVID-19 Testing
Generic Testing of Antigen Tests for COVID-19 in Denmark
To evaluate the analytical and clinical sensitivity and specificity of antigen tests performed as oropharyngeal swabs, outer nasal swabs, saliva swabs or breath tests including self-tests for SARS-CoV-2 towards standard RT-PCR…
- Trial name
- NCT04913116
- Testing
- Comparison of antigen tests with RT-PCR as reference method
- Where
- 3 sites in Denmark
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Telemedicine, Primary Health Care
Satellite-supplementation of Medical Outreach Clinics: a Feasibility Study
Much of the basic general medical care and chronic disease management in rural Honduras comes from groups of volunteers setting up temporary clinics run by volunteers.
- Conditions
- Telemedicine, Primary Health Care, Developing Countries, Diagnosis
- Trial name
- NCT01821014
- Testing
- Telemedicine, In-person physician interaction
- Where
- Honduras
- Volunteers
- 144 people
- Sponsor
- Mayo Clinic
Heart Failure With Preserved Ejection Fraction (HFpEF)
Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition
The correlation of coronary microvascular function and body composition with cardiopulmonary exercise capacity will be assessed in patients with heart failure with preserved ejection fraction.
- Trial name
- NCT04822649
- Testing
- Adenosine stress echocardiography with the evaluation of coronary artery blood flow
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Korea University Anam Hospital