Clinical trials: Age Problem
Older Adults, Age Problem
Influence and Relationships Between Square-stepping Exercise and Brain Activation, Cognitive Function, Physical Performance in Healthy Older Adults
Background and purposes: Square-stepping exercise (SSE) has been proved to be an effective intervention for motor and cognitive function in older adults. However, the underlying mechanism of SSE still remains undetermined.
- Trial name
- NCT05891574
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Disease, Fall Patients
Nature-based Therapy Program for Parkinson's Disease (PARC)
The goal of this clinical trial is to learn if a nature-based program has positive effects on the physical and psychosocial health in a group of participants with Parkinson's disease.
- Conditions
- Chronic Disease, Fall Patients, Aging Problems, Parkinson Disease
- Trial name
- PARC (NCT06452043)
- Testing
- PARC program
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Université du Québec à Chicoutimi
Aging Problems
Effect of a New HA Filler in Correcting Nasolabial Fold
The investigators aimed to evaluate the efficacy and safety of new HA filler for nasolabial fold correction
- Trial name
- NCT06574750
- Testing
- CUREAⓇ (ARIBIO, Ltd., Seoul, Republic of Korea), JuvedermⓇ (Q-Med AB, Uppsala, Sweden)
- Where
- South Korea
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Fall Injury, Age Problem
CatchU: A Quantitative Multisensory Falls-Assessment Study
The ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. To date, only a few studies have investigated the clinical translational value of multisensory…
- Conditions
- Fall Injury, Age Problem, Well Aging, Sensory Disorders
- Trial name
- CatchU (NCT05544760)
- Testing
- CatchU Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Central Auditory Processing Disorder, Hearing Impaired (Partially)
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD).
- Conditions
- Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality
- Trial name
- CAPD-LOOT (NCT07304024)
- Testing
- Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Growth Hormone Disorder, Growth Hormone Deficiency in Children
Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone
This study is conducted in Europe. The purpose of this study is to assess the impact on daily life for children new to using a growth hormone injection device.
- Conditions
- Growth Hormone Disorder, Growth Hormone Deficiency in Children, Genetic Disorder, Turner Syndrome
- Trial name
- NCT01327924
- Testing
- Norditropin NordiFlex®
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Novo Nordisk A/S
Aging Disorder, Aging Problems
Effects of Footwear Suitability on Functional Performance and Balance in Elderly
Proper footwear serves to protect the foot against external factors. Balance and functional performance are affected by the level of footwear suitability.
- Conditions
- Aging Disorder, Aging Problems, Aging
- Trial name
- NCT04151654
- Testing
- Footwear Assessment Score
- Volunteers
- 154 people
- Sponsor
- Tuba Maden
Sickle Cell Disease
Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell Disease
This study aims to develop an effective, brief, family-based intervention targeting quality of life and school functioning for youth with sickle cell disease.
- Trial name
- FTC (NCT02273310)
- Testing
- Problem-Solving Skills Training for Disease Management
- Volunteers
- 83 people
- Sponsor
- University of Pennsylvania
Laughter, Mental Health Issue
The Effect of Laughter Therapy on the Mental Health of Elderly Living in a Nursing Home
This study was designed and conducted as a randomized controlled experimental research with a pre-test and post-test control group to evaluate the effect of laughter therapy on psychological well-being, life satisfaction, and…
- Conditions
- Laughter, Mental Health Issue, Life Satisfaction, Well-Being, Psychological
- Trial name
- NCT06722872
- Testing
- Laughter therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Aging Problems, Coordination Impairment
Effects of Jaques-Dalcroze Eurhythmics Program on Postural Stability in Elderly Women.
This study investigated the effect of exercise using the Emil Jaques-Dalcroze's method on the postural stability of women over 65 years of age. The study model was based on a randomized controlled trial - parallel group design.
- Trial name
- NCT05015777
- Testing
- Emil Jaques-Dalcroze's Eurhythimcs Exercise Program
- Where
- Poland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Aging Problems, Aging
Evaluating the Safety and Efficacy of Autologous Adipose Tissue-derived Mesenchymal Stem Cell Transplantation on Proinflammatory Cytokines and Anti-inflammatory Cytokines on Ageing-related Low-grade Inflammation Patients.
Single-group, open-label, phase I / II clinical trial: Evaluation of the safety of autologous adipose tissue-derived mesenchymal stem cell transplantation in inflammaging (Ageing-related low-grade inflammation) patients.
- Conditions
- Aging Problems, Aging, Chronic Inflammation
- Trial name
- NCT05827757
- Testing
- autologous adipose-derived mesenchymal stem cell transplantation
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- DNA International Hospital
Dyslexia, Aging Problems
Neuroplasticity of Multisensory Cortical Areas Induced by Musical Training: a Translational Approach (MusicPlast)
Exploiting recent methodological advancements, several neuroimaging studies suggested that multisensory integration emerges from a dynamic interplay of distributed regions operating in large-scale networks.
- Trial name
- MusicPlast (NCT03786185)
- Testing
- MusicPlast, MusicPlast Control
- Where
- Greece
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Infant, Premature, Diseases, Perinatal Morbidity
Prognosis of Extremely Premature Birth
Pregnant women at risk of giving birth before 28 weeks' gestational age will be enrolled. Fetal circulation will be studied and blood for inflammatory parameters will be collected.
- Conditions
- Infant, Premature, Diseases, Perinatal Morbidity, Development, Problem;Growth
- Trial name
- BabyPEP (NCT01150396)
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- University of Bergen
Age Problem
The SUMAMOS EXCELENCIA Project: Assessment of Implementation of Best Practices in a National Health System
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Trial name
- NCT03725774
- Testing
- GRIP (Getting Research into Practice) model
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Aging Problems
Effectiveness of the Pilates Method to Prevent and Reduce Falls in Older People
The present research aims at evidencing the effect of one of the training methodologies increasingly demanded by the older adult, and used to promote, maintain and enhance physical and biopsychosocial aspects.
- Trial name
- NCT03299374
- Testing
- Pilates Intervention, Fall prevention intervention
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cognitive Impairment, Aging Problems
Effectiveness of a Strength Program Over Cognitive Functionality in Older Adults
This is a randomized, parallel, double-blind clinical trial. The main objective is to compare the efficacy of strength training, multimodal exercise with non-specific exercises and a control group on cognitive functionality and…
- Trial name
- NCT06434857
- Testing
- Strength training in older adults with mild or non existent cognitive impairment, Multimodal excercise in older adults with mild or non existent cognitive impairment
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Osteoarthritis, Knee, Aging Problems
OKV Versus CKC for Biomechanics and Function in Mild Knee OA Patients
Background: Clinical recommendations suggest exercises as the core treatment for knee osteoarthritis (OA) patients. However, the biomechanical modification following exercise therapy and its influence on pain remains unclear.
- Trial name
- NCT04678609
- Testing
- Exercise
- Where
- Malaysia
- Volunteers
- 66 people
- Sponsor
- Universiti Sains Malaysia
Growth Hormone Disorder, Growth Hormone Deficiency in Children
Safety and Efficacy of Long-term Somatropin Treatment in Children
This study is conducted in Europe. The aim of this study is to evaluate safety during the long-term use of somatropin (Norditropin®) in children as well as efficacy on change in height.
- Conditions
- Growth Hormone Disorder, Growth Hormone Deficiency in Children, Foetal Growth Problem, Small for Gestational Age
- Trial name
- GrowthWIN II (NCT01543867)
- Testing
- somatropin
- Where
- Germany
- Volunteers
- 5,442 people
- Sponsor
- Novo Nordisk A/S
Cognitive Decline, Age Problem
Clinical Outcomes in Elderly Patients With Preoperative Cognitive Dysfunction
Preexisting cognitive impairment, such as mild cognitive impairment, is common in many elderly patients who undergoing major surgeries.
- Conditions
- Cognitive Decline, Age Problem, Outcome
- Trial name
- NCT03143595
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhongda Hospital
Cognitive Impairment, Dementia
Hainan Community Cognition Cohort
This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up.
- Conditions
- Cognitive Impairment, Dementia, Age Problems
- Trial name
- NCT06686186
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hainan Medical College