Clinical trials: Affect
Healthy
A Study in Healthy Men to Find Out How Well Different Doses of BI 764122 Are Tolerated and Whether Food Affects the Amount of BI 764122 in the Blood
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 764122 in healthy male subjects following oral administration of single rising doses.
- Trial name
- NCT03794323
- Testing
- BI 764122
- Where
- Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pregnancy, Childbirth and Postpartum
Effectiveness of a Mindfulness and Compassion Intervention for Pregnant Women and Their Partners for the Prevention of Stress and Depression During Pregnancy and Breastfeeding
The aim of this study is to assess a mindfulness and compassion group intervention for pregnant women and their partners (8 weeks) for the prevention, reduction and treatment of stress, negative affect and depression in pregnancy…
- Trial name
- NCT03247491
- Testing
- Mindfulness
- Where
- Spain
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Javier Garcia Campayo
Chronic Kidney Disease, Hypertension
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
Researchers are looking for a better way to treat people who have chronic kidney disease (CKD), a progressive decrease in the kidneys' ability to work properly.
- Trial name
- NCT05491642
- Testing
- BAY3283142
- Where
- 4 sites in Bulgaria, Germany
- Volunteers
- 56 people
- Sponsor
- Bayer
Osteopathic Manual Manipulation of Neurovascular Regulation
Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System
The purpose this study is to determine which manual medicine technique or combination of techniques has the greatest effect on the natural changes in heart rate.
- Trial name
- NCT02193373
- Testing
- Osteopathic Manual Medicine
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Diabetic Peripheral Neuropathy
Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy
The purpose of this study is to see if an investigational drug known as the lidocaine 5% patch is safe and effective in reducing the symptoms of diabetic neuropathy, to examine how topical lidocaine affects the nerve endings, and…
- Trial name
- NCT01086150
- Testing
- Skin biopsy, Lidocaine 5% patches
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Congenital Heart Disease
Does Modified Ultrafiltration Affect Thromboelastography Results?
The study is to evaluate the effect of modified ultrafiltration on different components of Thromboelastography (TEG) in neonates undergoing cardiac surgery using cardiopulmonary bypass.
- Trial name
- NCT03214120
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
CTS
Pre-operative Sonographic Assessment of The Median Nerve in Carpal Tunnel Syndrome. Does it Affect The Operative Procedure?
Sonographic Assessment of The Median Nerve in Carpal Tunnel Syndrome to assess the surgical importance and added value of superficial ultrasonography in assessment of the median nerve in CTS.
- Trial name
- NCT03082027
- Testing
- ultrasonography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Borderline Personality Disorder (BPD), Healthy Controls Group - Age and Sex-matched
Affect-based Impulsivity in Borderline Personality Disorder
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old.
- Trial name
- NCT06880640
- Testing
- Stress Induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Pain, Pain
Can Medical Cannabis Affect Opioid Use?
The goal of this observational study is to learn how medical cannabis (MC) affects pain and the use of opioid pain medications. Participants who have chronic pain and use prescribed opioid pain medication will opt-in to using MC…
- Trial name
- NCT06206252
- Testing
- Medical Cannabis
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Thomas Jefferson University
Overweight and Obesity, Affect
Evaluation of the BOKS Before-school Physical Activity Program
BOKS, Build Our Kids' Success, is a before-school physical activity program that has been implemented in over 2,000 elementary and middle schools.
- Conditions
- Overweight and Obesity, Affect, Physical Activity, Fitness
- Trial name
- NCT03190135
- Testing
- BOKS: 2 day a week before-school physical activity program, BOKS: 3 day a week before-school physical activity program
- Where
- 3 sites in United States
- Volunteers
- 1,250 people
- Sponsor
- Massachusetts General Hospital
Postmenopausal, Female
How Seasons Affect Kidney Health in Post-Menopausal Females
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group.
- Trial name
- NCT06866743
- Testing
- There will be no intervention.
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Florida State University
Ischemic Stroke
Affect of Health Education on Statins Medication Persistence and ClinicaL Prognosis of Ischemic Stroke Patients (HELP)
The purpose of this study is to assess the affect of multiple health education interventions for statins medication Persistence and clinical prognosis of ischemic stroke patients at 3, 6 and 12 months.
- Trial name
- NCT02140658
- Testing
- multiple health education interventions, conventional health education
- Where
- China
- Volunteers
- 3,111 people
- Sponsor
- yongjun wang
Type 2 Diabetes
Examining the Effects of Diet on Health With an Online Program
The study is a pilot, designed to provide data regarding the feasibility and acceptability of conducting such a study on a larger scale.
- Trial name
- NCT01967992
- Testing
- Behavioral: Low Carbohydrate, Ketogenic Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
Cognitive Impairment, Pulmonary Rehabilitation
Does Cognitive Status Affect Pulmonary Rehabilitation Gains?
Pulmonary rehabilitation program with aerobic and strengthening trainings for 3 months will be applied to the candidates for lung transplantation.
- Trial name
- NCT03740867
- Testing
- Pulmonary rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital
Athletic Performance
Study on How Pre-Workout Supplements Affect Shooting Accuracy in Trained Basketball Players
Basketball is a popular team sport where athletes score points by successfully shooting the ball into the basket. Accuracy in shooting is crucial for players to score points effectively.
- Trial name
- NCT06995209
- Testing
- Pre-workout Supplement
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- International Hellenic University
Breast Reconstruction
Do Closed Suction Drains Affect the Complications Rate of Breast Reconstruction With Silicone Prosthesis?
The purpose of this study is to describe the relations between closed suction drains placement in breast reconstructions procedures with silicone prothesis to the development of local wound complications (seroma, hematoma…
- Trial name
- NCT00973544
- Testing
- Cultures taken from the drain discharge
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Depression
Treatment, Emotion, and Neuromodulation of Depression (TREND) Study
The investigators will administer theta burst stimulation (TBS) in efforts to observe a decrease in severity of reported depression symptoms. A subset of participants will receive positive affect training during this intervention.
- Trial name
- TREND (NCT05436379)
- Testing
- Theta Burst Stimulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Erika Forbes
Bleeding Nose
Nebulized Tranexamic Acid in Sinus Surgery
The results of several recent studies on endoscopic sinus surgery through topical administration of tranexamic acid are encouraging in terms of the efficacy of tranexamic acid for intraoperative bleeding and other pathological…
- Trial name
- NCT04905901
- Testing
- Tranexamic acid
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Anesthesia; Adverse Effect, Newborn Morbidity
Does the Mode of Anesthesia Affect the Feto-maternal Outcome in Category-1 Caesarean Section
Spinal anesthesia (SA) has become the standard technique in elective cesarean section (CS) as it results in less maternal and neonatal morbidity than general anesthesia (GA) (Grade-A recommendation, NICE).
- Trial name
- NCT04634981
- Testing
- anesthesia of emergency cesarean section
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Benha University
Hyperglycemia, Diabetes Mellitus
Management of Hyperglycemic Patients in Emergency Medicine Department
The main purpose of this study is how to manage hyperglycemic patients in emergency departments, to determine the conditions that require blood glucose regulation and to examine the prognosis of the patients in the next 30 days…
- Conditions
- Hyperglycemia, Diabetes Mellitus, Emergencies
- Trial name
- NCT04665128
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Derince Training and Research Hospital