Clinical trials: Adverse Pregnancy Outcome
First Trimester Bleeding, Pregnancy
Early Pregnancy Evaluation by Three-Dimensional Ultrasound
Early pregnancy is associated with numerous physiologic alterations - many of which are required to establish normal pregnancy outcome.
- Trial name
- NCT00342290
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Birth Outcome, Adverse
Knowledge, Attitudes, and Practices of Operative Vaginal Birth Among Obstetric Providers in Egypt
The goal of this observational study is to evaluate the knowledge, attitudes, and practices of operative vaginal birth among obstetric providers in Egypt.
- Trial name
- NCT06502119
- Testing
- Designed Questionnaire
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gestational Diabetes, Pregnancy Complications
Gestational Diabetes Monitoring and Management
The primary goal is to predict the clinical outcomes of mother and baby using blood glucose and other routinely collected clinical data in pregnancy to predict adverse outcomes at birth in women with GDM.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT06963528
- Where
- United Kingdom
- Volunteers
- 1,800 people
- Sponsor
- University of Oxford
Birth Outcome, Adverse, Self Efficacy
The Door to the Womb at Birth: Haptonomy
Purpose: This study aimed to examine the effect of haptonomy application on the expectant mother's birth expectations, experiences, birth self-efficacy, birth memory and reminder during labor.
- Conditions
- Birth Outcome, Adverse, Self Efficacy, Memory Impairment, Pregnancy Related
- Trial name
- NCT06508554
- Testing
- Haptonomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Trakya University
Aplastic Anemia, Pregnancy
A Prediction Model in Pregnant Women With Aplastic Anemia
Aplastic anemia (AA) is a rare haematologic disorder characterized by bone marrow failure and pancytopenia. Its occurrence during pregnancy is exceedingly rare but poses significant risks, including maternal hemorrhage…
- Conditions
- Aplastic Anemia, Pregnancy, Prediction Model
- Trial name
- NCT07101770
- Testing
- A combined retrospective and prospective observational follow-up
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)
Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes
The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute.
- Trial name
- TIPS (NCT01975792)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Pre-Eclampsia
Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy
Relation of certain maternal serum antibodies to Doppler changes will be studied in cases suffering from hypertension with pregnancy.
- Trial name
- NCT03214393
- Testing
- Doppler, serum antibodies
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
IBD (Inflammatory Bowel Disease), IBD
Exploring Fecal Calprotectin Levels, Maternal and Infant Microbiota, Infant Health, Nutrition, and Adverse Pregnancy Outcomes With Patient With Inflammatory Bowel Disease
The goal of this prospective longitudinal cohort study is to examine how the human microbiome of pregnant women-including bacteria and fungi in the gastrointestinal tract, vaginal canal, skin, and breastmilk-may influence infant…
- Conditions
- IBD (Inflammatory Bowel Disease), IBD, IBD - Inflammatory Bowel Disease, Pregnancy
- Trial name
- CALINA-IBD (NCT07385807)
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Adverse Pregnancy Outcomes
The Mechanism of Adverse Pregnancy Outcomes Influenced by Maternal Air Pollution Exposure
This research evaluates the effects of maternal exposure to air pollution during pregnancy on adverse pregnancy outcomes, the general demographic information, the level of maternal exposure to air pollution, pregnancy-related…
- Trial name
- NCT04215406
- Testing
- The level of air pollution
- Where
- China
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Birth Outcome, Adverse, Birth, First
The Peanut Ball Use on Labor
The purpose of this study was to evaluate the effect of using peanut balls during labor on labor memory, labor satisfaction, labor length, and neonatal APGAR scores.
- Conditions
- Birth Outcome, Adverse, Birth, First, Labor Long, Apgar; 4-7 at 1 Minute
- Trial name
- NCT06387680
- Testing
- The Effect of Peanut Ball Use on Labor Memory, Labor Satisfaction, Delivery Length, and Neonatal APGAR Score: A Randomized Controlled Trial
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pregnancy Complications
Diamine Oxidase and Adverse Pregnancy Outcomes
In normal pregnancies, blood histamine concentration remains within normal values; however, the serum histaminolytic activity is increased.
- Trial name
- NCT06281366
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Maternal Health, Child Health
Boston Birth Cohort Study
Early life exposures may lead to adverse effects on health in later life. The Boston birth Cohort study is designed to study a broad array of early life factors and their effects on maternal and child health outcomes across the…
- Conditions
- Maternal Health, Child Health, Pregnancy Complications, Birth Outcome, Adverse
- Trial name
- NCT03228875
- Where
- United States
- Volunteers
- 24,000 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Preterm Premature Rupture of Membranes, Fetal Inflammatory Response Syndrome
Multimodal Monitoring of Fetal Risk of Inflammation in Preterm Premature Rupture of Membranes
The purpose of this study is to examine whether the value of vaginal fluid cytokine levels as well as computerized fetal ECG analysis are suitable clinical parameters to detect an imminent intra-amniotic inflammation with a high…
- Conditions
- Preterm Premature Rupture of Membranes, Fetal Inflammatory Response Syndrome, Early Onset Neonatal Sepsis, Infection of Amniotic Cavity
- Trial name
- MuMFI-PPROM (NCT02702297)
- Testing
- single arm
- Where
- 4 sites in Germany
- Volunteers
- 57 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Hypertriglyceridemia During Pregnancy
The Effect of Lifestyle Intervention for Hypertriglyceridemia on the Pathogenesis of Adverse Pregnancy Outcome
During pregnancy, hypertriglyceridemia is associated with adverse pregnancy outcomes, including gestational hypertension, preeclampsia, gestational diabetes mellitus, large for gestational age (LGA), and preterm delivery.
- Trial name
- NCT04275622
- Testing
- Lifestyle including optimal exercise and diet modification.
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Maternal Mortality, Perinatal Mortality
Evaluation of a Smartphone Application to Reduce Adverse Pregnancy Outcomes in Ethiopia
The purpose of this trial is to determine if the safe delivery smartphone application distributed to health workers in Ethiopia will decrease perinatal mortality and the incidence of postpartum haemorrhage.
- Trial name
- NCT01945931
- Testing
- Safe Delivery Smartphone Application
- Where
- Denmark
- Volunteers
- 3,601 people
- Sponsor
- University of Copenhagen
HIV Infections, Pregnancy Related
Pregnancy in Women With HIV Infection
Women living with HIV face multiple challenges regarding pregnancy, encompassing not only their intention to procreate, but also difficulties during the course of pregnancy.
- Trial name
- NCT04350554
- Testing
- Pregnancy
- Volunteers
- 160 people
- Sponsor
- Carlos III Health Institute
Anemia
Serum Hepcidin in Pregnant Women and the Association With Pregnancy Outcome
Hepcidin production is normally upregulated by iron stores, and in obesity has been shown to be overexpressed and correlated with low iron status.
- Trial name
- NCT03792464
- Where
- Switzerland
- Volunteers
- 188 people
- Sponsor
- University Hospital, Basel, Switzerland
Preterm Birth Complication
Prediction of Adverse Outcome Using Fetal MRI in Pregnancies at Risk of Preterm Birth
1.4% of babies have a very premature birth (PTB) (less than 32 weeks of pregnancy). This can result in severe life-long complications including cerebral palsy, learning and behavioural difficulties and breathing problems.
- Trial name
- NCT05164432
- Testing
- MRI scan
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- King's College London
Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy
Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes
The objective of our study is to investigate the association of umbilical cord abnormalities with adverse pregnancy outcomes. The umbilical cord parameters that will be investigated as part of this study include the umbilical…
- Conditions
- Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy, Stillbirth, Admission to Neonatal Unit
- Trial name
- ULOOP (NCT05901688)
- Testing
- Umbilical cord measurements & observations
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Medway NHS Foundation Trust
HIV Infections
Multivitamin Dosage Regimens in the Prevention of Adverse Pregnancy Outcomes Among HIV-Positive Women
The purpose of this study is to examine effects of daily administration of multivitamin supplements at doses resembling the Recommended Dietary Allowance (RDA) during pregnancy to HIV positive women decreases the risks of low…
- Trial name
- NCT00197678
- Testing
- Multivitamins-Multiples of RDA, Multivitamins-Single RDA
- Where
- United States
- Volunteers
- 1,141 people
- Sponsor
- Harvard School of Public Health (HSPH)