Clinical trials: Adverse Cardiac Event
Cardiovascular Diseases, Atherosclerosis
Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD
A growing body of evidence supports associations between cardiovascular health and adverse pregnancy outcome and between adverse pregnancy outcome and atherosclerotic cardiovascular disease and builds on the well-established…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Pregnancy Complications, Adverse Cardiac Event
- Trial name
- CVD_OBS (NCT06406998)
- Testing
- Pre-existing atherosclerotic cardiovascular disease
- Where
- South Korea
- Volunteers
- 5,461,222 people
- Sponsor
- Samsung Medical Center
Major Adverse Cardiac Events, Cerebrovascular Accident
Construction of a Prediction Model for MACCE in Elderly Patients After Elective Non-cardiac Surgery
Severe cardiovascular and cerebrovascular complications, including cardiac death, non-fatal angina/myocardial infarction, non-fatal heart failure, stroke, severe arrhythmia, etc., are one of the main types of postoperative…
- Conditions
- Major Adverse Cardiac Events, Cerebrovascular Accident, Postoperative Complications, Models
- Trial name
- NCT06391632
- Testing
- Revised Cardiac Risk Index
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Stem Cell Transplant Complications, Acute Graft Versus Host Disease
Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study
This study aims to establish a cohort of 500 patients with hematological disease who undergoing allogeneic hematopoietic stem cell transplantation in the northwest region.
- Conditions
- Stem Cell Transplant Complications, Acute Graft Versus Host Disease, Acute Kidney Injury, Major Adverse Cardiac Events
- Trial name
- NCT06386445
- Testing
- Serum metabolomics sequencing
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Diabetes Mellitus, Type 2, Major Adverse Cardiac Events
Effect of Patient Management Based on Continuous Continuous Glucose Monitoring on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes and Moderate to Severe Coronary Artery Stenosis
Patients with type 2 diabetes and moderate to severe coronary artery stenosis who were treated at Zhejiang Second Hospital and cooperative hospitals were randomly divided into a patient management group based on continuous…
- Trial name
- NCT06060483
- Testing
- CGM
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Haemodialysis Complication, Major Adverse Cardiac Events
Novel Cardiovascular Biomarkers in Patients With Kidney Disease
Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should. End-stage kidney failure (ESKD) is the final, irreparable stage of chronic kidney disease (CKD), where kidney function…
- Trial name
- CBKD (NCT06037759)
- Testing
- Cardiac Biomarkers, Lipidomics, Proteomics
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Ventricular Dysfunction, Left, Major Adverse Cardiac Events
Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery
Elderly patients are the fastest growing surgical population and have an increased risk of postoperative cardiac problems. Diastolic dysfunction, or the reduced ability of the heart' s ventricles to fill completely, is common in…
- Trial name
- NCT01780727
- Testing
- EGHEM
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Nebraska
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Incidence of Major Adverse Cardiac Events
Registry Experience at the Washington Hospital Center With Drug Eluting Stents - Synergy
To compare the incidence of major adverse cardiac events among a series of patients receiving the Synergy drug-eluting stent with bioabsorbable polymer to historical controls who have received the Promus Premier drug-eluting…
- Trial name
- NCT02823730
- Testing
- PCI with Synergy Stent
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Medstar Health Research Institute
Myocardial Infarction, Myocardial Injury
Colchicine Prevents Myocardial Injury After Non-Cardiac Surgery Pilot Study
Perioperative Myocardial Infarction (PMI) is a major contributor to perioperative mortality and morbidity with overall incidence of 5-16%.
- Conditions
- Myocardial Infarction, Myocardial Injury, Major Adverse Cardiac Events, Infectious Complications
- Trial name
- COPMAN (NCT04139655)
- Testing
- Colchicine 0.6 mg
- Where
- Canada
- Sponsor
- University of British Columbia
OSA, ACS - Acute Coronary Syndrome
Impact of OSA on Outcomes in Acute Coronary Syndrome
Elucidating the effects of obstructive sleep apnea (OSA) on cardiovascular outcomes in acute coronary syndrome (ACS) is crucial in risk assessments and therapeutic recommendations for affected individuals.
- Conditions
- OSA, ACS - Acute Coronary Syndrome, Major Adverse Cardiac Events
- Trial name
- ISAACS (NCT03793582)
- Testing
- ApneaLink Type III portable sleep study
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- MetroHealth Medical Center
Risks of Adverse Events After Cardiac Surgery
The Perioperative Risks of Adverse Events After Cardiac Surgery: a Retrospective Study
Cardiac surgeries under cardiopulmonary bypass (CPB) are a major treatment for heart valve disease and coronary artery disease, and over 1-1.25 million such procedures are performed annually worldwide.
- Trial name
- PRAECS (NCT04476134)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Lei Du
Peri-operative Stroke, Perioperative Adverse Events
Incidence and Risk Factors of Peri-operative Stroke in Non-cardiac,Non-neurosurgical Surgeries
Stroke is an important cause of perioperative morbidity and mortality, particularly in patients > 60 years. In cardiac, neurological and carotid surgery the incidence is known to be high (2.2-5.2%).
- Conditions
- Peri-operative Stroke, Perioperative Adverse Events, Non-cardiac Surgery, Non-neurosurgical Surgery
- Trial name
- POSIC (NCT01758952)
- Where
- 6 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Chinese Medical Association
Adverse Reactions, Immune Checkpoint Inhibitor
Cardiac Adverse Reactions Related to Immune Checkpoint Inhibitor in NSCLC Patients
This is a prospective, open label, single arm study. A total of 300 patients with primary non-small cell lung cancer treated with PD-1/PD-L1 immune checkpoint inhibitors(ICIs) are expected to included .
- Conditions
- Adverse Reactions, Immune Checkpoint Inhibitor, Non-Small Cell Lung Cancer Patients, Cardiac Event
- Trial name
- NCT04473703
- Testing
- renin-angiotensin system inhibitors or angiotensin-receptor-neprilysin inhibitor
- Volunteers
- 300 people
- Sponsor
- Shanghai Chest Hospital
Carotid Stenosis, Carotid Endarterectomy
Major Adverse Cardiac Events After Carotid Endarterectomy
Carotid endarterectomy is the operation for curing the significant carotid artery stenotic patients who are also at high cardiac risk. This retrospective study is to find out the incidence and risk factors related.
- Conditions
- Carotid Stenosis, Carotid Endarterectomy, Adverse Cardiac Events
- Trial name
- NCT03596229
- Where
- Thailand
- Volunteers
- 175 people
- Sponsor
- Mahidol University
Arterial Closure Device, Percutaneous Coronary Intervention (PCI)
Femoral Closure Versus Radial Compression Devices Related to Percutaneous Coronary Interventions Study
FERARI is a single centre observational study comparing patients undergoing PCI either using radial compression devices or femoral closure devices at the corresponding access site.
- Conditions
- Arterial Closure Device, Percutaneous Coronary Intervention (PCI), Access Site Bleeding, Adverse Cardiac Events
- Trial name
- FERARI (NCT02455661)
- Testing
- TR Band (TM), AngioSeal, StarClose
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Universitätsmedizin Mannheim
Major Adverse Cardiac-cerebral-kidney Event
MACE and First Operating Room Systolic Blood Pressure in Patients Undergoing Non-cardiac Surgery Implications for the Hypertension Threshold
To find the threshold of First operating room SBP above which MACE risk increases.
- Trial name
- NCT03185598
- Volunteers
- 90,342 people
- Sponsor
- Peking University First Hospital
Adverse Event, Physiotherapy
Adverse Events During Physiotherapy at Intensive Care Unit In Patients Undergoing Cardiac Surgery
This study aims to estimate the incidence of adverse events during physiotherapy at intensive care unit (ICU) in adult patients undergoing cardiac surgery and to identify predictors of those events.
- Conditions
- Adverse Event, Physiotherapy, Intensive Care Units, Cardiac Surgery
- Trial name
- Adephysio (NCT03552887)
- Testing
- Cardiac Surgery, Physiotherapy
- Volunteers
- 323 people
- Sponsor
- University of Sao Paulo General Hospital