Clinical trials: Adult Angiosarcoma, active
Osteosarcoma, Bone Tumor
Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas
The Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas (COSS-Registry) is a non-interventional, multicentric, international, clinical and epidemiologic patient registry.
- Conditions
- Osteosarcoma, Bone Tumor, Bone Sarcoma, High Grade Sarcoma
- Trial name
- COSS-Registry (NCT05515068)
- Volunteers
- 1,000 people
- Sponsor
- Klinikum Stuttgart
Adult Pleomorphic Rhabdomyosarcoma, AJCC Grade 2 Sarcoma
Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue Sarcoma
This phase III trial compares chest computed tomography (CT) to chest x-ray (CXR) for lung surveillance after curative-intent resection of high-risk truncal-extremity soft tissue sarcoma.
- Conditions
- Adult Pleomorphic Rhabdomyosarcoma, AJCC Grade 2 Sarcoma, AJCC Grade 3 Sarcoma, Alveolar Soft Part Sarcoma
- Trial name
- NCT06526897
- Testing
- Biopsy, Chest Computed Tomography, Chest Radiography
- Volunteers
- 1,582 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Angiosarcoma, Angiosarcoma, Adult
Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for Angiosarcoma
This is a multicenter, open-label study of Intratumoral Vusolimogene Oderparepvec (VO) to investigate safety and estimate when used in combination with pembrolizumab for treating participants with angiosarcoma.
- Trial name
- NCT06898970
- Testing
- Vusolimogene Oderparepvec (VO), Pembrolizumab
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Varun Monga, MBBS
Soft Tissue Sarcoma Adult, Angiosarcoma
Propranolol and Pembrolizumab in Advanced Soft Tissue Sarcoma Patients
The goal of this phase 2 clinical trial is to test efficacy and tolerability of combining propranolol and pembrolizumab in patients with advanced angiosarcoma or undifferentiated pleomorphic sarcoma.
- Conditions
- Soft Tissue Sarcoma Adult, Angiosarcoma, Undifferentiated Pleomorphic Sarcoma
- Trial name
- PROPANE (NCT05961761)
- Testing
- Propranolol, Pembrolizumab
- Where
- 4 sites in Denmark, Norway and 1 more
- Volunteers
- 80 people
- Sponsor
- Niels Junker
Sarcoma, Sarcoma, Leiomyo-, Adult
Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients
This is a cohort study aimed at developing a stratified medicine approach for personalised neoadjuvant chemotherapy (NCT) in high-risk soft tissue sarcoma (STS) patients with dedifferentiated liposarcoma (DDLPS), leiomyosarcoma…
- Conditions
- Sarcoma, Sarcoma, Leiomyo-, Adult, Sarcoma, Synovial, Adult, Soft Tissue Sarcoma (STS)
- Trial name
- PANTHR-S (NCT07432932)
- Testing
- Observational Translational Study
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Royal Marsden NHS Foundation Trust