Clinical trials: Adolescent Development
Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis
Development of a Conservative Care and Bracing Registry (CCBR)
Idiopathic scoliosis (IS) is a common problem affecting approximately 3% of the population; its progression can lead to significant health problems.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis, Juvenile Idiopathic Scoliosis, Infantile Idiopathic Scoliosis
- Trial name
- CCBR (NCT07527611)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- National Scoliosis Center
Scoliosis Idiopathic Adolescent Treatment
Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility
Scoliosis bracing is an effective treatment method for idiopathic scoliosis, but only if worn consistently for many hours a day. Unsurprisingly, brace discomfort is a significant deterrent against treatment adherence.
- Trial name
- 3DSCOLIBRACE (NCT06785207)
- Testing
- 3D-printed scoliosis brace
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder, Repetitive Compulsive Behavior
Amitriptyline for Repetitive Behaviors in Autism Spectrum Disorders
The investigators will recruit 30 children and adolescents (15 per group x 2 groups) aged 6 to 17 years with ASD and significant repetitive behaviors that cause problems to them and to others around them.
- Trial name
- NCT04725383
- Testing
- amitriptyline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Tuberous Sclerosis Complex
Basimglurant (NOE-101) in Children, Adolescents, and Young Adults With TSC
The study intends to show that basimglurant (NOE-101) provides effective seizure control in children, adolescents and young adults with Tuberous Sclerosis Complex (TSC).
- Trial name
- NCT05059327
- Where
- 27 sites in United States, India and 6 more
- Volunteers
- 61 people
- Sponsor
- Noema Pharma AG
Osteogenesis Imperfecta
Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta
The primary objective of this trial is to evaluate the safety of romosozumab in participants with osteogenesis imperfecta (OI) that have completed Study 20200105, regardless of whether they received investigational product…
- Trial name
- NCT07366086
- Testing
- Vitamin D, Calcium
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 71 people
- Sponsor
- Amgen
Autism, Developmental Disabilities
Magnetic Resonance Imaging in Children and Adolescents With Autism and Multiple Complex Developmental Disorders
This study aims to investigate the overlap and differences between autism and MCDD as neuropsychiatric childhood disorders. MRI scans are acquired from subjects with autism, subjects with a diagnosis of MCDD and typically…
- Trial name
- NCT00161135
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Violence, Adolescent
Addressing Root Causes for Gun Violence Prevention (ARC-GVP)
The goal of this study is to help build the evidence base for a locally-relevant youth firearm violence prevention program in Washington D.C., a city experiencing disparities in youth firearm violence outcomes.
- Conditions
- Violence, Adolescent, Firearm Injury, Aggression
- Trial name
- NCT05887973
- Testing
- The T.R.I.G.G.E.R Project
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Autism Spectrum Disorder
Evaluation of the Effect of a Social Skills Program for Children and Adolescents With ASD
Research evaluating effectiveness of social skills intervention programs for children and adolescents with Autism Spectrum Disorder is still limited.
- Trial name
- NCT05713162
- Testing
- Adaptation of the Social Adjustment Enhancement Intervention of the UC Davis MIND Institute (Solomon, 2004).
- Where
- Spain
- Volunteers
- 94 people
- Sponsor
- Fundació Sant Joan de Déu
Obsessive Compulsive Disorder
Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES)
To evaluate the long-term impact of treatment with sertraline on aspects of cognitive, emotional and physical development and pubertal maturation in pediatric subjects ages 6 to 16 years (inclusive) with a diagnosis of anxiety…
- Trial name
- SPRITES (NCT01302080)
- Testing
- sertraline, psychotherapy
- Where
- 44 sites in United States
- Volunteers
- 941 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acquired Immunodeficiency Syndrome
Intervention for HIV-Positive Black Young Men Who Have Sex With Men (YMSM)
This study involves conducting formative research to develop a culturally appropriate secondary prevention intervention for HIV-positive Black young men who have sex with men (B-YMSM).
- Trial name
- NCT01502618
- Testing
- Focus Group
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
CASCADE: CAnnabidiol Study in Children With Autism Spectrum DisordEr
This is a randomized, placebo-controlled study but all study participants will receive the active study medication at some point during the study for at least 12 weeks, and some children with receive CBD for the entire study.
- Trial name
- CASCADE (NCT04520685)
- Testing
- Oral cannabidiol 100mg/mL
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder, Oxytocin
Understanding Oxytocin's Neural and Behavioral Effects in Adolescents Diagnosed With Autism
The investigators explored the neural and behavioral effect of oxytocin on youth with Autism spectrum disorder using magnetoencephalography (MEG).
- Trial name
- NCT05096676
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Prof. Ilanit gordon
Autistic Disorders Spectrum, Sexual Behavior
Sexaffectivity in Autistic Spectrum Disorder
The WHO defines sexual health as a state of physical, emotional, mental and social well-being, related to sexuality, not only the absence of illness, dysfunction or disability.
- Conditions
- Autistic Disorders Spectrum, Sexual Behavior, Adolescent Development, Sexual Inadequacy
- Trial name
- NCT03625609
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Parc Taulí Hospital Universitari
Autism Spectrum Disorder
Improving Transition Outcomes for Youth With ASD in a Medicaid Accountable Care Organization
Despite an increasing number of children with Autism Spectrum Disorder (ASD), fragmentation across child and adult service systems results in poor education, employment and health outcomes for transition-aged youth (TAY).
- Trial name
- NCT04869540
- Testing
- Usual care, 'Got Transition' toolkit and resources, PSE intervention
- Sponsor
- Boston Medical Center
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Autism
Social Cognition in Children and Adolescents With Autism Spectrum Disorder
This study aims to (1) characterize the multi-domain social cognitive profile and developmental trajectory of children with autism spectrum disorder (ASD) aged 2.5 to 14 years relative to typically developing peers; (2) establish…
- Trial name
- NCT07692022
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Malignant Neoplasm
Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents
This randomized trial studies how well music therapy and parents' education work in improving communication, emotional distress, and recovery in adolescents/young adult patients undergoing treatment for high-risk cancer and their…
- Trial name
- NCT01556256
- Testing
- Caregiver-Related Intervention or Procedure, Music Therapy, Quality-of-Life Assessment
- Where
- 8 sites in United States
- Volunteers
- 124 people
- Sponsor
- Children's Oncology Group
Adolescent Behavior, Stress Reduction
CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention
Using an adapted stress-reduction intervention called the CEDARS, the investigators will pilot the intervention in adolescents (N=40) to determine the feasibility and acceptability of CEDARS implementation and to investigate…
- Conditions
- Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
- Trial name
- CEDARS (NCT04958694)
- Testing
- CEDARS
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Autism Spectrum Disorders
Improving Participation of Autistic Children and Adolescents in the Habilitation Process
This project aims to explore the impact of a survey-based and a meeting-based needs assessment models on 7 to 17 year old autistic children's participation in the needs assessment process at the initial reception when enrolled at…
- Trial name
- IMPAC (NCT06381856)
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Örebro County
Physical Inactivity, Sedentary Behavior
ASDactive: An Integrated Theory-based Intervention to Promote Habitual Physical Activity
ASDactive is a theory-based behaviour change intervention aimed at improving the physical activity behaviours of autistic youth.
- Conditions
- Physical Inactivity, Sedentary Behavior, Autism, Autism Spectrum Disorder
- Trial name
- ASDactive (NCT05958680)
- Testing
- ASDactive
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University